Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vera L Silva"'
Autor:
Vera L Silva, Debora Ferreira, Franklin L Nobrega, Ivone M Martins, Leon D Kluskens, Ligia R Rodrigues
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161290 (2016)
The use of bacteriophages to select novel ligands has been widely explored for cancer therapy. Their application is most warranted in cancer subtypes lacking knowledge on how to target the cancer cells in question, such as the triple negative breast
Externí odkaz:
https://doaj.org/article/4bc14f04d2e64bd9bb4b2178f7e40875
Autor:
Vera L. Silva, Jayeta Saxena, Francesco Nicolini, Joseph I. Hoare, Stephen Metcalf, Sarah A. Martin, Michelle Lockley
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Abstract High-grade serous cancer (HGSC) accounts for ~67% of all ovarian cancer deaths. Although initially sensitive to platinum chemotherapy, resistance is inevitable and there is an unmet clinical need for novel therapies that can circumvent this
Externí odkaz:
https://doaj.org/article/f776a5bc88df48608017c058a6820cc6
Publikováno v:
Brazilian Journal of Development. 6:20073-20089
Com a evolucao das TICs transformando imponentemente, incluindo e mudando as relacoes sociais dos cidadaos, consequentemente as Instituicoes de Ensino almejam acompanhar, imagina-se deixando-os interligados globalmente, assim como, na atualidade, “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b36ece0262baa6ee872d497235cbe8
https://doi.org/10.34117/bjdv6n4-253
https://doi.org/10.34117/bjdv6n4-253
Autor:
Francesco Nicolini, Sarah A. Martin, Vera L. Silva, Joseph I. Hoare, Jayeta Saxena, Michelle Lockley, Stephen Metcalf
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
High-grade serous cancer (HGSC) accounts for ~67% of all ovarian cancer deaths. Although initially sensitive to platinum chemotherapy, resistance is inevitable and there is an unmet clinical need for novel therapies that can circumvent this event. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7ba9c9dc4dd68f979999180dcb2829
https://pubmed.ncbi.nlm.nih.gov/33854036
https://pubmed.ncbi.nlm.nih.gov/33854036
Autor:
Quitéria Ferreira da Silva, Domingos pascoal, Magna Cristina de Oliveira Silva, Nátally Maria Carneiro Daher Cabral, Maria José dos Santos, Patrícia Pereira da Silva, Ademilson Leandro Correia, Edilson Zezito dos Santos, Bruno Pereira Silva, Gabrielly do Prado Silva, Josinaldo André de Souza, Emily Gabrielly Sotero Gomes, Natan Ferreira, Iara de Souza Rocha, Joalisson Leonardo Vieira Silva, Charlan Fialho dos Santos, Maria de Lourdes Fernandes, Evanilson Oliveira de Santana, Rosa Maria da Silva Gonçalves, Edson Fernando da Silva, José Barros dos Anjos, Claudio Dortas Araújo, Carla Daniely Silveira Santos, Cicero Thiago Sotero da Silva, João Paulo Gomes, Edionaldo Gonçalves de Souza, Antonio Charles Melo Feijão, Bruna Pereira Silva, Luiz Felipe Simplicio dos Santos, Damião Barros dos Santos, Carlindo de Lira Pereira, Janielma Conceição Alves, Maria Aparecida da S Carvalho, Marcello André Fausto Souza, Osny Donizate Nunes de Almeida, Renato de Menezes Pereira, Silvano Gabriel Pereira de Barros Santos, Andréia Araújo Menezes, Edcleidson de Souza Sá, Rafaela Silva de Oliveira, José Dhavi Alves Gerônimo Barbosa, Cauany Gabriely Medrade de Aragão, Daniela Soares Menezes, Jayne Oliveira Brandão, Paula Pereira da Silva, Cheiene Damázio Uggioni, Caio César Sampaio Ubirajara, Natália Pâmela Barbosa Ribeiro, Ana Carla Rodrigues Oliveira, Luis Laercio Geronimo Pereira, Carmem Fabiana Nunes da Silva, Edvaldo Santos Felix, Franciele Cavalcante dos Santos, Ana Vitória da Costa Almeida, Fabiana Felix Cordeiro, Ivana Maria Tavares Costa, Maria Emília Barbosa Albuquerque, Vania Marcia Gomes Barbosa de Almeida, José Gemaque P de S e S Neto, José Ginaldo de Jesus, Alexsandro de Lima Pereira, Jania Maria Souza da Silva, Pietro Lemos Costa, Josué Portugal Duarte, Maria Simone Soares da Silva, M Vera L Silva Rocha, Luciana Bispo Cavalcante, Denilson De Souza Santos, Rogério Fernandes Lemes, Idelbrando Gutemberg dos Santos, Valdemira de Albuquerque Araújo, Ciro Pimentel Veras, Maria Aparecida de Lima, Eliana da Silva, Maria Virgínia de Assunção Feitosa Gomes, Lívia Limeira Alves, Erisvaldo Soares de Freitas, Rhadly Edy Silva, Maxwel da Conceição Santos, Maria Eduarda Leite de Matos, Danyelle Cruz Schetine, Yago Beserra Marinho Martins, Iara da Silva Gomes, Maria Aparecida Carneiro de Carvalho, Beatriz Santos Trindade, Alexandra Silva Lacerda, Luciene Torres de Albuquerque, Bruno Vinícius Santos Pinheiro, Jéssica Oliveira Alencar, Hélio de Souza Oliveira, Cosmo Dartanhan M de Holanda Cavalcante, Ronaldo Crispim dos Santos, Manoel Josenias de Oliveira, Rosielly de Araújo Cavalcante, Caroline Rebeca Mariano Vilela, Odilon dos Anjos, Isrraela Rodrigues Alves, Antônio Marcos Bandeira, Willys Soares da Silva, Rosa Ramos Regis da Silva, Amanda Giselle Gomes Silva, Diógenes Rodrigues Pereira, Vanessê Gonzaga de Almeida, Davi Hellí Maciel Veloso, Cristina Sales da Conceição Brandão
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c17d0d331818a1dd5500546d6dadf4
https://doi.org/10.29327/525272
https://doi.org/10.29327/525272
Autor:
Maja Severic, Ashkan Dehsorkhi, Duuamene Nyimanu, Abdessamad. Y. Kaassis, Cédrik-Roland Koffi, Christopher J. Morris, Moustafa Abdelhamid, Wafa' T Al-Jamal, Vera L Silva
Publikováno v:
Silva, V L, Kaassis, A, Dehsorkhi, A, Koffi, C-R, Severic, M, Abdelhamid, M, Nyimanu, D, Morris, C J & Al-Jamal, W T 2020, ' Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper-tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer ', Biomaterials science . https://doi.org/10.1039/c9bm01905g
In the present work, a copper-tirapazamine (TPZ) nanocomplex [Cu(TPZ)2] was synthesized for selective hypoxia-targeted therapy. The nanocomplex revealed a crystalline form, and exhibited higher lipophilicity, compared to TPZ. Furthermore, its stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af14f342dbfebbc6bebfa5fabf36ad64
https://ueaeprints.uea.ac.uk/id/eprint/74483/
https://ueaeprints.uea.ac.uk/id/eprint/74483/
Autor:
Wafa' T Al-Jamal, Jani Seitsonen, Ahlam A. Ali, Amalia Ruiz, Fiona Furlong, Janne Ruokolainen, Vera L Silva, Jonathan A. Coulter, Sara Pereira
Publikováno v:
Silva, V L, Ruiz, A, Ali, A, Pereira, S, Seitsonen, J, Ruokolainen, J, Furlong, F, Coulter, J & Al-Jamal, W T 2021, ' Hypoxia-targeted cupric-tirapazamine liposomes potentiate radiotherapy in prostate cancer spheroids ', International journal of pharmaceutics, vol. 607, 121018 . https://doi.org/10.1016/j.ijpharm.2021.121018
Funding Information: V.L.S is grateful for her PhD studentship awarded by the University of East Anglia (studentship ref. 100099479). This work was also supported by the Prostate Cancer UK (CDF-12-002 Fellowship), the Engineering and Physical Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d10f817546d425881a28937c33e35c
https://doi.org/10.1016/j.ijpharm.2021.121018
https://doi.org/10.1016/j.ijpharm.2021.121018
Autor:
Vera L Silva, Wafa' T Al-Jamal
Publikováno v:
Silva, V L & Al-Jamal, W T 2017, ' Exploiting the cancer niche: Tumor-associated macrophages and hypoxia as promising synergistic targets for nano-based therapy ' Journal of controlled release : official journal of the Controlled Release Society, vol. 253, pp. 82-96 . DOI: 10.1016/j.jconrel.2017.03.013
The tumor microenvironment has been widely exploited as an active participant in tumor progression. Extensive reports have defined the dual role of tumor-associated macrophages (TAMs) in tumor development. The protumoral effect exerted by the M2 phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a275a0543846a92bb77a2ff3e0ee8e4
https://pure.qub.ac.uk/portal/en/publications/exploiting-the-cancer-niche-tumorassociated-macrophages-and-hypoxia-as-promising-synergistic-targets-for-nanobased-therapy(fe8ba231-95b7-4e98-a07a-ed418672a853).html
https://pure.qub.ac.uk/portal/en/publications/exploiting-the-cancer-niche-tumorassociated-macrophages-and-hypoxia-as-promising-synergistic-targets-for-nanobased-therapy(fe8ba231-95b7-4e98-a07a-ed418672a853).html