Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Vera Hilden"'
Autor:
Baoyan Bai, Jillian F. Wise, Daniel Vodák, Sigve Nakken, Ankush Sharma, Yngvild Nuvin Blaker, Marianne Brodtkorb, Vera Hilden, Gunhild Trøen, Weicheng Ren, Susanne Lorenz, Michael S. Lawrence, Ola Myklebost, Eva Kimby, Qiang Pan-Hammarström, Chloé B. Steen, Leonardo A. Meza-Zepeda, Klaus Beiske, Erlend B. Smeland, Eivind Hovig, Ole Christian Lingjærde, Harald Holte, June Helen Myklebust
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Follicular lymphoma (FL) is the most common indolent type of B-cell non-Hodgkin lymphoma. Advances in treatment have improved overall survival, but early relapse or transformation to aggressive disease is associated with inferior outcome. To
Externí odkaz:
https://doaj.org/article/92e65d15b9924346a5867a14c377ae05
Autor:
Nicole Bethge, Hilde Honne, Kim Andresen, Vera Hilden, Gunhild Trøen, Knut Liestøl, Harald Holte, Jan Delabie, Guro E Lind, Erlend B Smeland
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e104249 (2014)
Epigenetic modifications and DNA methylation in particular, have been recognized as important mechanisms to alter gene expression in malignant cells. Here, we identified candidate genes which were upregulated after an epigenetic treatment of B-cell l
Externí odkaz:
https://doaj.org/article/3eb29c33ebaf456881f85e59f3a4f756
Autor:
Nicole Bethge, Hilde Honne, Vera Hilden, Gunhild Trøen, Mette Eknæs, Knut Liestøl, Harald Holte, Jan Delabie, Erlend B Smeland, Guro E Lind
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79602 (2013)
Epigenetic alterations of gene expression are important in the development of cancer. In this study, we identified genes which are epigenetically altered in major lymphoma types. We used DNA microarray technology to assess changes in gene expression
Externí odkaz:
https://doaj.org/article/169fcba64d864e41a75c17b191cbfd08
Autor:
Baoyan Bai, Jillian F. Wise, Daniel Vodák, Sigve Nakken, Ankush Sharma, Yngvild Nuvin Blaker, Marianne Brodtkorb, Vera Hilden, Gunhild Trøen, Weicheng Ren, Suzanne Lorenz, Michael S. Lawrence, Ola Myklebost, Eva Kimby, Qiang Pan-Hammarstrom, Leonardo Meza-Zepeda, Klaus Beiske, Erlend B. Smeland, Eivind Hovig, Ole Christian Lingjærde, Harald Holte, June Helen Myklebust
Publikováno v:
Blood. 140:6411-6412
Autor:
Erlend B. Smeland, Eivind Hovig, Lars Birger Aasheim, Ragnhild A. Lothe, Daniel Vodak, Ole Christian Lingjærde, Jillian F. Wise, Yngvild Nuvin Blaker, Sirpa Leppä, Gunhild Trøen, Annika Pasanen, Bjarne Johannessen, Michael S. Lawrence, Harald Holte, Leonardo A. Meza-Zepeda, Susanne Lorenz, June Helen Myklebust, Vera Hilden, Sigve Nakken, Chloé B. Steen, Baoyan Bai, Ola Myklebost, Anita Sveen, Klaus Beiske
Publikováno v:
Blood Adv
Key Points Diagnostic and relapse diffuse large B-cell lymphoma (DLBCL) biopsies reveal increased mutational burden/loss of heterozygosity in HLA-A. Serially sampled tumor biopsies provide insight into therapeutic targets and evolutionary divergence
Autor:
June Helen Myklebust, Vera Hilden, Børre Fevang, Johanna Olweus, Kjetil Taskén, Pål Aukrust, Eli Taraldsrud, Silje F. Jørgensen, Kristine Moltu
Publikováno v:
Journal of Autoimmunity. 81:110-119
Common variable immunodeficiency (CVID) is defined by hypogammaglobulinemia and B-cell dysfunction, with significant clinical and immunological heterogeneity. Severe non-infectious complications, such as autoimmunity, granulomatous disease and spleno
Autor:
Sirpa Leppä, Harald Holte, Michael S. Lawrence, Lars Birger Aasheim, June Helen Myklebust, Vera Hilden, Klaus Beiske, Baoyan Bai, Bjarne Johannessen, Yngvild Nuvin Blaker, Sigve Nakken, Leonardo A. Meza-Zepeda, Jillian F. Wise, Erlend B. Smeland, Annika Pasanen, Chloé B. Steen, Eivind Hovig, Ragnhild A. Lothe, Anita Sveen, Ola Myklebost, Ole Christian Lingjærde, Daniel Vodák, Gunhild Trøen, Suzanne Lorenz
Publikováno v:
Blood. 134:1497-1497
Introduction Relapses of diffuse large B-cell lymphoma typically occur within 2-3 years and only 10% of these patients reach a 3-year progression-free survival compared to 65% at diagnosis. Our ability to distinguish patients at risk for relapse rema
Autor:
June Helen Myklebust, Lise Forfang, So Yoon, Erlend B. Smeland, Kanutte Huse, Sébastien Wälchli, Vera Hilden, Baoyan Bai, Morten P. Oksvold, Lise Kristin Bollum
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0177188 (2017)
PLoS ONE, Vol 12, Iss 5, p e0177188 (2017)
Selection and maturation of B cells into plasma cells producing high-affinity antibodies occur in germinal centers (GC). GCs form transiently in secondary lymphoid organs upon antigen challenge, and the GC reaction is a highly regulated process. TGF-
Autor:
Vera Hilden, Ole Christian Lingjærde, Kanutte Huse, Marit E. Hystad, Erlend B. Smeland, Andreas Rosenwald, June Helen Myklebust, Jan Delabie, Gunhild Trøen, Harald Holte, Ellen Leich, Marianne Brodtkorb
Publikováno v:
Blood. 123:1051-1054
Transformation of follicular lymphoma (FL) to a more aggressive disease is associated with rapid progression and death. Existing molecular markers for transformation are few and their clinical impact is limited. Here, we report on a whole-genome stud
Autor:
Harald Holte, Vera Hilden, Erlend B. Smeland, Per Olaf Ekstrøm, Gustav Gaudernack, Knut Liestøl, Olav Erich Yri
Publikováno v:
Leukemia & Lymphoma. 54:2205-2214
We analyzed the allelic distribution of 12 candidate polymorphisms in a large retrospective study of 486 patients with diffuse large B-cell lymphoma (DLBCL) treated at Oslo University Hospital with 1056 blood donors serving as controls. Variants in T