Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vera Gindikin"'
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 709 (2019)
DNA repeat domains implicated in DNA expansion diseases exhibit complex conformational and energy landscapes that impact biological outcomes. These landscapes include ensembles of entropically driven positional interchanges between isoenergetic, isom
Externí odkaz:
https://doaj.org/article/60573dfbe26541619e406cc650705f7a
Publikováno v:
Biopolymers. 101:1-12
Repetitive DNA sequences exhibit complex structural and energy landscapes, populated by metastable, non-canonical states, that favor expansion and deletion events correlated with disease phenotypes. To probe the origins of such genotype-phenotype lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f022742db5ee838ac41cc473368e4963
https://doi.org/10.1002/bip.22236
https://doi.org/10.1002/bip.22236
Publikováno v:
The FASEB Journal. 10:164-170
We have measured at 25 degrees C the relative specific sound velocity increment, [u], and the partial specific volume, v degrees, of cytochrome c as a function of pH. Our data reveal that the base-induced native to unfolded transition of the protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e38f6ddd3665cf955900afb8a25e892
https://doi.org/10.1096/fasebj.10.1.8566538
https://doi.org/10.1096/fasebj.10.1.8566538
Publikováno v:
Journal of the American Chemical Society
DNA repeat domains can form ensembles of canonical and noncanonical states, including stable and metastable DNA secondary structures. Such sequence-induced structural diversity creates complex conformational landscapes for DNA processing pathways, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc55b89b20ded4aa0e9615defeb4ff4b
https://pubmed.ncbi.nlm.nih.gov/22397401
https://pubmed.ncbi.nlm.nih.gov/22397401
Publikováno v:
Biopolymers. 101:439-439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40329ea9706d3fae7bb50a30a149b032
https://doi.org/10.1002/bip.22451
https://doi.org/10.1002/bip.22451
Publikováno v:
Biophysical chemistry. 75(1)
We have determined the apparent molar volumes and the apparent molar adiabatic compressibilities at 25°C of 10 X–Gly–Gly and Gly–Gly–X tripeptides in which X represents a residue with a non-polar side chain. We also have determined the chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68150e9a7904a749443782853f4bf64
https://pubmed.ncbi.nlm.nih.gov/17027457
https://pubmed.ncbi.nlm.nih.gov/17027457
Publikováno v:
Journal of molecular biology. 250(2)
Cytochrome c can exist in a native (N), a molten globule (MG) or an unfolded (U) state depending on solution conditions. We have used high-precision ultrasonic and densimetric techniques to measure volume and compressibility changes accompanying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ce8d24a046d607bfb59e24cd1179ca
https://pubmed.ncbi.nlm.nih.gov/7608975
https://pubmed.ncbi.nlm.nih.gov/7608975
Publikováno v:
Biophysical Journal. (2):77a
Triplet repeat DNA sequences are prone to undergo DNA expansion events that correlate with a range of debilitating neurological diseases such as Huntington's and myotonic dystrophy type 1 (DM1). Repeat DNA expansion occurs in response to error prone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280aca8560061048109ac4ac104c0b8c