Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vera Gesheva"'
Autor:
Andrey Tchorbanov, Krassimira Idakieva, Nikolina Mihaylova, Stela Chausheva, Vera Gesheva, Nadia Stefanova, L. Doumanova
Publikováno v:
International Immunopharmacology. 26:162-168
Background New generated subunit vaccines are characterized by increased safety and lack of side effects, however they suffer from weak immunogenicity. The adjuvants are substances that have the ability to enhance the magnitude and duration of the im
Autor:
Vera Gesheva
Publikováno v:
Iore Journal of Immunology. 1:01-03
Autor:
Andrey Tchorbanov, Vera Gesheva, Nikola Kerekov, Maria Nikolova, Kalina Nikolova, Nikolina Mihaylova, Todor A. Todorov
Publikováno v:
Autoimmunity. 47:162-172
Self-specific B cells play a main role in the pathogenesis of lupus. This autoimmune disease is characterized by the generation of autoantibodies against self antigens, and the elimination of B and T cells involved in the pathological immune response
Autor:
Vera Gesheva, Todor A. Todorov, Tchavdar L. Vassilev, Reinhard E. Voll, Kalina A. Nikolova-Ganeva
Publikováno v:
Clinical and Experimental Immunology. 174:221-228
Summary Targeting autoreactive B lymphocytes at any stage of their differentiation could yield viable therapeutic strategies for treating autoimmunity. All currently used drugs, including the most recently introduced biological agents, lack target sp
Autor:
Andrey Tchorbanov, Maria Nikolova, Zsuzsanna Szekeres, Nikolina Mihaylova, Vera Gesheva, Iliyana Dimitrova, Anna Erdei, József Prechl
Publikováno v:
Human Gene Therapy Methods. 23:357-365
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the development of self-reactive B and T cells and autoantibody production. In particular, double-stranded DNA-specific B cells play an important role in lupus progression,
Autor:
L. Doumanova, Andrey Tchorbanov, Nikola Kerekov, Krassimira Idakieva, Nikolina Mihaylova, Vera Gesheva, Kalina Nikolova
Publikováno v:
Fish & Shellfish Immunology. 30:135-142
Killed viral vaccines and bacterial toxoids are weakly immunogenic. Numerous compounds are under evaluation as immunological adjuvants and peptide-carriers to improve the immune response. The hemocyanins, giant extracellular copper proteins in the bl
Autor:
Andrey Tchorbanov, Iliyan Manoylov, Stela Chausheva, Vera Gesheva, Nikolina Mihaylova, Krassimira Idakieva, L. Doumanova
Publikováno v:
BMC Immunology
Background Various immunotherapeutic approaches have been used for the treatment of cancer. A number of natural compounds are designed to repair, stimulate, or enhance the immune system response. Among them are the hemocyanins (Hcs) - extracellular c
Autor:
Andrey Tchorbanov, Maria Nikolova, Kalina Nikolova, Iliyana Dimitrova, Nikolina Mihaylova, Vera Gesheva, Todor A. Todorov
Publikováno v:
Lupus. 19(11)
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the generation of autoantibodies against a diverse array of self-antigens. The B cells producing immunoglobulin G (IgG) antibodies to double-stranded DNA appear to play a ma
Autor:
Nikolina Mihaylova, Elisaveta Voynova, Kalina Nikolova, Nikola Kerekov, Vera Gesheva, Andrey Tchorbanov, Maria Nikolova, József Prechl
Publikováno v:
Autoimmunity reviews. 9(7)
DNA-specific B cells in SLE represent a logical target for therapeutic intervention. We hypothesize that it is possible to re-establish tolerance to native DNA in SCID mice with cells transferred from SLE patients or from lupus-prone MRL/lpr mice by