Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vera G Lelianova"'
Autor:
Nickolai V Vysokov, John-Paul Silva, Vera G Lelianova, Jason Suckling, John Cassidy, Jennifer K Blackburn, Natalia Yankova, Mustafa BA Djamgoz, Serguei V Kozlov, Alexander G Tonevitsky, Yuri A Ushkaryov
Publikováno v:
eLife, Vol 7 (2018)
A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic interaction that contributes to synapse formation. Surprisingly, during neuronal developmen
Externí odkaz:
https://doaj.org/article/e3ab38e5ab3145c8b2d8316c81bfd8a3
Autor:
Antonio Vitobello, Benoit Mazel, Vera G. Lelianova, Alice Zangrandi, Evelina Petitto, Jason Suckling, Vincenzo Salpietro, Robert Meyer, Miriam Elbracht, Ingo Kurth, Thomas Eggermann, Ouafa Benlaouer, Gurprit Lall, Alexander G. Tonevitsky, Daryl A. Scott, Katie M. Chan, Jill A. Rosenfeld, Sophie Nambot, Hana Safraou, Ange-Line Bruel, Anne-Sophie Denommé-Pichon, Frédéric Tran Mau-Them, Christophe Philippe, Yannis Duffourd, Hui Guo, Andrea K. Petersen, Leslie Granger, Amy Crunk, Allan Bayat, Pasquale Striano, Federico Zara, Marcello Scala, Quentin Thomas, Andrée Delahaye, Jean-Madeleine de Sainte Agathe, Julien Buratti, Serguei V. Kozlov, Laurence Faivre, Christel Thauvin-Robinet, Yuri Ushkaryov
Publikováno v:
Am J Hum Genet
ADGRL1/latrophilin-1, a well-characterized adhesion G protein-coupled receptor, has been implicated in synaptic development, maturation and activity. However, the role of ADGRL1 in human disease has been elusive. Here, we describe 10 individuals with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd4a155399f4d282e04e1b905624a55
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience
Frontiers in Neuroscience
Latrophilin-1 (LPHN1) was isolated as the main high-affinity receptor for α-latrotoxin from black widow spider venom, a powerful presynaptic secretagogue. As an adhesion G-protein-coupled receptor, LPHN1 is cleaved into two fragments, which can beha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d79e14bda28eda0804499620ec0bed
https://www.frontiersin.org/article/10.3389/fnins.2019.00257/full
https://www.frontiersin.org/article/10.3389/fnins.2019.00257/full
Autor:
John H. Cassidy, Yuri A. Ushkaryov, Nickolai Vysokov, Jennifer K. Blackburn, John-Paul Silva, Jason Suckling, Vera G. Lelianova, Natalia Yankova, Serguei V Kozlov, Alexander G. Tonevitsky, Mustafa B. A. Djamgoz
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic interaction that contributes to synapse formation. Surprisingly, during neuronal developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4986b89125746641bf5c32de3be3c904
https://kar.kent.ac.uk/69740/11/elife-37935-v1.pdf
https://kar.kent.ac.uk/69740/11/elife-37935-v1.pdf
Autor:
Alexander G. Tonevitsky, Serguei V Kozlov, Natalia Yankova, Yuri A. Ushkaryov, John-Paul Silva, Vera G. Lelianova, Mustafa B.A. Djamgoz, Nickolai Vysokov, Jennifer K. Blackburn, Jason Suckling, John H. Cassidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c66c15423d37522ec9484abc31f94282
https://doi.org/10.7554/elife.37935.028
https://doi.org/10.7554/elife.37935.028
Autor:
Mustafa B. A. Djamgoz, Yuri A. Ushkaryov, Claudia Ho, John-Paul Silva, Vera G. Lelianova, Alexander G. Tonevitsky, Nickolai Vysokov
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Teneurins are large cell-surface receptors involved in axon guidance. Teneurin-2 (also known as latrophilin-1-associated synaptic surface organizer (Lasso)) interacts across the synaptic cleft with presynaptic latrophilin-1, an adhesion G-protein-cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f10ba65091564a6526a497637efd30
http://hdl.handle.net/10044/1/39066
http://hdl.handle.net/10044/1/39066
Publikováno v:
Journal of Biological Chemistry. 284:6495-6506
The unusual adhesion G-protein-coupled receptors (aGPCRs) contain large extracellular N-terminal domains, which resemble cell-adhesion receptors, and C-terminal heptahelical domains, which may couple to G-proteins. These receptors are cleaved post-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586dd9abf907863c69b9e9c1c6ef8686
https://doi.org/10.1074/jbc.m806979200
https://doi.org/10.1074/jbc.m806979200
Autor:
John-Paul Silva, Colin R. Hopkins, M. Atiqur Rahman, Yuri A. Ushkaryov, Kirill E. Volynski, Vera G. Lelianova
Publikováno v:
The EMBO Journal. 23:4423-4433
Heptahelical, or G-protein-coupled, receptors control many cellular functions and normally consist of one polypeptide chain. In contrast, heptahelical receptors that belong to the long N-terminus, group B (LNB) family are cleaved constitutively into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d974188ac530285847cf699cae9569
https://doi.org/10.1038/sj.emboj.7600443
https://doi.org/10.1038/sj.emboj.7600443
Autor:
C Manser, J. O. Dolly, Eugene V. Grishin, Tatyana Volkova, Richard H. Ashley, EE Dudina, Kirill E. Volynski, Frederic A. Meunier, Vera G. Lelianova, Yuri A. Ushkaryov, M A Rahman
Publikováno v:
Journal of Biological Chemistry. 275:41175-41183
Pure alpha-latrotoxin is very inefficient at forming channels/pores in artificial lipid bilayers or in the plasma membrane of non-secretory cells. However, the toxin induces pores efficiently in COS-7 cells transfected with the heptahelical receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8dfaf5e0e23571b26c8a339babe570
https://doi.org/10.1074/jbc.m005857200
https://doi.org/10.1074/jbc.m005857200
Autor:
Catherine Van Renterghem, Michael Seagar, Yuri A. Ushkaryov, Vera G. Lelianova, Nicole Martin-Moutot, Cécile Iborra
Publikováno v:
European Journal of Neuroscience. 12:3953-3962
In order to explore the mechanisms by which alpha-latrotoxin activates neurotransmitter release, we have characterized its effects by patch-clamp methods on cells heterologously expressing its receptors, latrophilin-1 or neurexin-Ialpha. Application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a36231d88323ce94ef0a1b3f5d4b26f
https://doi.org/10.1046/j.1460-9568.2000.00282.x
https://doi.org/10.1046/j.1460-9568.2000.00282.x