Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vera E Golimbet"'
Autor:
Dmitrii A. Abashkin, Dmitry S. Karpov, Artemii O. Kurishev, Ekaterina V. Marilovtseva, Vera E. Golimbet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15746 (2023)
Schizophrenia (SZ) is a common psychiatric neurodevelopmental disorder with a complex genetic architecture. Genome-wide association studies indicate the involvement of several transcription factors, including ASCL1, in the pathogenesis of SZ. We aime
Externí odkaz:
https://doaj.org/article/9eeb74e3a3c04ca19106b76553f59e8f
Autor:
Artemiy O. Kurishev, Dmitry S. Karpov, Nonna I. Nadolinskaia, Anna V. Goncharenko, Vera E. Golimbet
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 241 (2022)
The study of diseases of the central nervous system (CNS) at the molecular level is challenging because of the complexity of neural circuits and the huge number of specialized cell types. Moreover, genomic association studies have revealed the comple
Externí odkaz:
https://doaj.org/article/3f0908fd492d439a8c6f5d42de6acd52
Publikováno v:
Cells, Vol 10, Iss 11, p 3184 (2021)
Scientifically interesting as well as practically important phenotypes often belong to the realm of complex traits. To the extent that these traits are hereditary, they are usually ‘highly polygenic’. The study of such traits presents a challenge
Externí odkaz:
https://doaj.org/article/b6e3c55e7ea542b684a78a5f7352b6b0
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8518 (2021)
Schizophrenia (SZ) is a prevalent functional psychosis characterized by clinical behavioural symptoms and underlying abnormalities in brain function. Genome-wide association studies (GWAS) of schizophrenia have revealed many loci that do not directly
Externí odkaz:
https://doaj.org/article/1ac77dd074064477a193fb511af39ad9
Autor:
Elena A. Zelenova, Nikolay V. Kondratyev, Tatyana V. Lezheiko, Grigoriy Y. Tsarapkin, Andrey I. Kryukov, Alexander E. Kishinevsky, Anna S. Tovmasyan, Ekaterina D. Momotyuk, Erdem B. Dashinimaev, Vera E. Golimbet
Publikováno v:
Cells, Vol 10, Iss 7, p 1690 (2021)
A major problem in psychiatric research is a deficit of relevant cell material of neuronal origin, especially in large quantities from living individuals. One of the promising options is cells from the olfactory neuroepithelium, which contains neuron
Externí odkaz:
https://doaj.org/article/37cd3b65bdc44ec5b1cfec7d433fdf1d
Autor:
Elizaveta S. Ershova, Oksana N. Agafonova, Natalia V. Zakharova, Lidia V. Bravve, Elizaveta M. Jestkova, Vera E. Golimbet, Tatiana V. Lezheiko, Anna Y. Morozova, Andrey V. Martynov, Roman V. Veiko, Pavel E. Umriukhin, Georgiy P. Kostyuk, Sergey I. Kutsev, Natalia N. Veiko, Svetlana V. Kostyuk
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Introduction: It was shown that copy number variations (CNVs) of human satellite III (1q12) fragment (f-SatIII) reflects the human cells response to stress of different nature and intensity. Patients with schizophrenia (SZ) experience chronic stress.
Externí odkaz:
https://doaj.org/article/07362bddecd548d8b16e69a198adbc30
Publikováno v:
Cells, Vol 9, Iss 1, p 246 (2020)
Recent advances in psychiatric genetics have led to the discovery of dozens of genomic loci associated with schizophrenia. However, a gap exists between the detection of genetic associations and understanding the underlying molecular mechanisms. This
Externí odkaz:
https://doaj.org/article/a79f5075feed4bf482c3880be28e732b
Autor:
Elena M. Malinovskaya, Elizaveta S. Ershova, Vera E. Golimbet, Lev N. Porokhovnik, Nataliya A. Lyapunova, Serguey I. Kutsev, Natalia N. Veiko, Svetlana V. Kostyuk
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Introduction: The multi-copied genes coding for the human 18, 5.8, and 28S ribosomal RNA (rRNA) are located in five pairs of acrocentric chromosomes forming so-called rDNA. Human genome contains unmethylated, slightly methylated, and hypermethylated
Externí odkaz:
https://doaj.org/article/7ce24087432c4ef89853860ffa0d6284
Publikováno v:
Schizophrenia Research and Treatment, Vol 2017 (2017)
Literature suggests that the effect of winter birth on vulnerability to schizophrenia might be mediated by increased expression of proinflammatory cytokines due to prenatal infection and its inadequate regulation by anti-inflammatory factors. As the
Externí odkaz:
https://doaj.org/article/fc416514268846e5ae90c44b6e912e19
Autor:
Margarita V, Alfimova, Svetlana G, Nikitina, Tatyana V, Lezheiko, Nataliya V, Simashkova, Vera E, Golimbet
Publikováno v:
Child psychiatry and human development.
The study explored whether schizophrenia risk alleles of the DRD2 rs2514218 and ZNF804A rs1344706 polymorphisms also influenced the risk and severity of childhood-onset schizophrenia (COS) and differentiated it from autism spectrum disorders (ASD). W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0bb6a59b36ea78af0d3ee1a80243c0c
https://pubmed.ncbi.nlm.nih.gov/34524581
https://pubmed.ncbi.nlm.nih.gov/34524581