Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Vera D Rinaldi"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009416 (2021)
Beyond the haploid genome, mammalian sperm carry a payload of epigenetic information with the potential to modulate offspring phenotypes. Recent studies show that the small RNA repertoire of sperm is remodeled during post-testicular maturation in the
Externí odkaz:
https://doaj.org/article/14b27601fe0b45368ddc484dd0ae983e
Autor:
Feng Wang, Maria Gracia Gervasi, Ana Bošković, Fengyun Sun, Vera D Rinaldi, Jun Yu, Mary C Wallingford, Darya A Tourzani, Jesse Mager, Lihua Julie Zhu, Oliver J Rando, Pablo E Visconti, Lara Strittmatter, Ingolf Bach
Publikováno v:
eLife, Vol 10 (2021)
The X-linked gene Rlim plays major roles in female mouse development and reproduction, where it is crucial for the maintenance of imprinted X chromosome inactivation in extraembryonic tissues of embryos. However, while females carrying a systemic Rli
Externí odkaz:
https://doaj.org/article/85c0317343a64841b13715f36fcb3890
Autor:
Vera D Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, Oliver J Rando
Publikováno v:
eLife, Vol 9 (2020)
Following testicular spermatogenesis, mammalian sperm continue to mature in a long epithelial tube known as the epididymis, which plays key roles in remodeling sperm protein, lipid, and RNA composition. To understand the roles for the epididymis in r
Externí odkaz:
https://doaj.org/article/1b5671ed738449c8a1945380abda0587
Autor:
Yu-Han Hung, Meghan Capeling, Jonathan W. Villanueva, Matt Kanke, Michael T. Shanahan, Sha Huang, Rebecca Cubitt, Vera D. Rinaldi, John C. Schimenti, Jason R. Spence, Praveen Sethupathy
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background MicroRNAs (miRNAs) are important post-transcriptional gene regulators controlling cellular lineage specification and differentiation during embryonic development, including the gastrointestinal system. However, miRNA-mediated regu
Externí odkaz:
https://doaj.org/article/02087dfb606b46d7bd6a6a50830c592e
Autor:
Yu-Han Hung, Meghan Capeling, Jonathan W. Villanueva, Matt Kanke, Michael T. Shanahan, Sha Huang, Rebecca L. Cubitt, Vera D. Rinaldi, John C. Schimenti, Jason R. Spence, Praveen Sethupathy
MicroRNAs (miRNAs) are important post-transcriptional gene regulators in organ development. To explore candidate roles for miRNAs in prenatal SI lineage specification in humans, we used a multi-omic analysis strategy in a directed differentiation mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17f5933fd0bd6d1675e1768cdc73be5a
https://doi.org/10.1101/2022.07.12.499825
https://doi.org/10.1101/2022.07.12.499825
Publikováno v:
Genetics
Unrepaired DNA damage in mouse oocytes leads to apoptosis, in part via CHK2 signaling to TRP53 and TRP63. Here, Rinaldi, Bloom, and Schimenti provide evidence that CHK1 can also be involved, especially... Eukaryotic organisms have evolved mechanisms
Autor:
Vera D. Rinaldi, Colin C. Conine, Oliver J. Rando, Fengyun Sun, Ryan W. Serra, Carolina Galan
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009416 (2021)
PLoS Genetics
PLoS Genetics
Beyond the haploid genome, mammalian sperm carry a payload of epigenetic information with the potential to modulate offspring phenotypes. Recent studies show that the small RNA repertoire of sperm is remodeled during post-testicular maturation in the
Autor:
Feng Wang, Darya A. Tourzani, Jun Yu, Ana Bošković, Maria Gracia Gervasi, Mary C. Wallingford, Lara Strittmatter, Ingolf Bach, Oliver J. Rando, Fengyun Sun, Pablo E. Visconti, Jesse Mager, Lihua Julie Zhu, Vera D. Rinaldi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4353044c824f5255ecefe2ebccfd696
https://doi.org/10.7554/elife.63556.sa2
https://doi.org/10.7554/elife.63556.sa2
Autor:
Oliver J. Rando, Fengyun Sun, Pablo E. Visconti, Mary C. Wallingford, Ana Bošković, Jesse Mager, Jun Yu, Maria Gracia Gervasi, Lihua Julie Zhu, Ingolf Bach, Vera D. Rinaldi, Lara Strittmatter, Darya A. Tourzani, Feng Wang
Publikováno v:
eLife, Vol 10 (2021)
The X-linked geneRlimplays major roles in female mouse development and reproduction, where it is crucial for the maintenance of imprinted X chromosome inactivation in extraembryonic tissues of embryos. However, while females carrying a systemicRlimkn
Autor:
Jordana C. Bloom, Matt Kanke, Nicolas Buchon, Michael J. Shanahan, Bailey C.E. Peck, Rebecca L. Cubitt, Lukas E. Dow, Breanna Sheahan, Shengli Ding, Wendy A. Pitman, Alessandro Bonfini, Praveen Sethupathy, Christopher M. Dekaney, Vera D. Rinaldi, Ennessa G. Curry, Elia D. Tait-Wojno, Ajeet Singh, Oyebola O. Oyesola, Adrian J. McNairn, Yu-Han Hung, Jonathan W. Villanueva, John C. Schimenti
SummaryThe role of individual miRNAs in small intestinal (SI) epithelial homeostasis is under-explored. In this study, we discovered that miR-375 is among the most enriched miRNAs in intestinal crypts and stem cells (ISCs), especially facultative ISC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc1408182c0c1329b8c1ce64f8c16cd6
https://doi.org/10.1101/2020.10.01.321612
https://doi.org/10.1101/2020.10.01.321612