Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vera C. Hirschfeld-Warneken"'
Publikováno v:
Nano Letters
Phenotyping of tumor cells by marker-free quantification is important for cancer diagnostics. For the first time, fractal analysis of reflection interference contrast microscopy images of single living cells was employed as a new method to distinguis
Publikováno v:
Biointerphases. 8(1)
Reflection interference contrast microscopy (RICM) allows the visualization of the cell's adhesion topology on substrates. Here it is applied as a new label-free method to measure adhesion forces between tumor cells and their substrate without any ex
Autor:
Vera C. Hirschfeld-Warneken, Stefanie Neubauer, Florian Rechenmacher, Sabri Ramouni, Viktoria Schaufler, Judit Guash, Rebecca Medda, Horst Kessler, Elisabetta Ada Cavalcanti-Adam, Joachim P. Spatz
Publikováno v:
Biophysical Journal. 104(2)
The coordination of specific functions of α5β1 and αvβ3 integrins is crucial for cell spreading and migration. For the spatio-temporal transduction of signals, cells interacting with their environment regulate the localization of α5β1 and αvβ
Autor:
Joachim P. Spatz, Israel Patla, Ohad Medalia, Tova Volberg, Nadav Elad, Reinhard Fässler, Vera C. Hirschfeld-Warneken, Carsten Grashoff, Benjamin Geiger
Publikováno v:
Journal of Cell Science
Integrin-mediated focal adhesions (FAs) are large, multi-protein complexes that link the actin cytoskeleton to the extracellular matrix and take part in adhesion-mediated signaling. These adhesions are highly complex and diverse at the molecular leve
Publikováno v:
Intelligent Surfaces in Biotechnology: Scientific and Engineering Concepts, Enabling Technologies, and Translation to Bio-Oriented Applications
This chapter contains sections titled: Introduction; Chemical Approaches for Protein; Immobilization; Biomolecule Patterning by “Top-Down” Techniques; Biomolecule Nanoarrays by Block Copolymer Nanolithography; Application of Nanostructured Surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f40ba8658be01f3a56f42143ab498b
https://hdl.handle.net/11858/00-001M-0000-0010-4AD5-611858/00-001M-0000-002C-897F-4
https://hdl.handle.net/11858/00-001M-0000-0010-4AD5-611858/00-001M-0000-002C-897F-4
Publikováno v:
Soft Matter Gradient Surfaces: Methods and Applications
This chapter contains sections titled: Introduction, In vitro templates to mimic the extracellular space, Induction of cell polarization, Cell migration-strategies to pursue gradients Sensitivity to respond to distance gradients, Conclusion, Referenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b492c5ba84a152766090174cef0a95
https://hdl.handle.net/11858/00-001M-0000-002C-97AC-411858/00-001M-0000-0010-4AE6-F
https://hdl.handle.net/11858/00-001M-0000-002C-97AC-411858/00-001M-0000-0010-4AE6-F
Publikováno v:
International Journal of Materials Research
Intillegent interfaces make use of a fundamental molecular unterstanding of biosystems for the induction of their specific responses. Biological cells espacially have an enormous spatial resolution for oranizing their transmembrane receptor molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2193d66cfb5f803d2f1fa92e2cf8f76a
https://hdl.handle.net/11858/00-001M-0000-0010-4DCE-211858/00-001M-0000-002C-93BF-7
https://hdl.handle.net/11858/00-001M-0000-0010-4DCE-211858/00-001M-0000-002C-93BF-7
Autor:
Vera C. Hirschfeld-Warneken, Joachim P. Spatz, Nadav Elad, Carsten Grashoff, Benjamin Geiger, Tova Volberg, Israel Patla, Reinhard Fässler, Ohad Medalia
Publikováno v:
Nature Cell Biology
Focal adhesions are integrin-based multiprotein complexes, several micrometres in diameter, that mechanically link the extracellular matrix with the termini of actin bundles. The molecular diversity of focal adhesions and their role in cell migration
Autor:
Igor Kitanovic, Vera C. Hirschfeld-Warneken, Humphrey Gardner, Stefan Woelfl, C. Lulu Bradford, Karin Gorgas, Kerry L. Tucker, Joachim P. Spatz, Marc August Willaredt, Kerstin Hasenpusch-Theil, Thomas Theil, Christian P Gojak
Publikováno v:
Mechanisms of Development. 126
Autor:
C. P. Gojak, I. Kitanovic, C. L. Bradford, Stefan Wölfl, Vera C. Hirschfeld-Warneken, Joachim P. Spatz, Thomas Theil, Kerstin Hasenpusch-Theil, H. A. R. Gardner, Kerry L. Tucker, K. Gorgas, M. A. Willaredt
Publikováno v:
Willaredt, M A, Hasenpusch-Theil, K, Gardner, H A R, Kitanovic, I, Hirschfeld-Warneken, V C, Gojak, C P, Gorgas, K, Bradford, C L, Spatz, J, Wolfl, S, Theil, T & Tucker, K L 2008, ' A Crucial Role for Primary Cilia in Cortical Morphogenesis ', Journal of Neuroscience, vol. 28, no. 48, pp. 12887-12900 . https://doi.org/10.1523/JNEUROSCI.2084-08.2008
The Journal of Neuroscience
The Journal of Neuroscience
Primary cilia are important sites of signal transduction involved in a wide range of developmental and postnatal functions. Proteolytic processing of the transcription factor Gli3, for example, occurs in primary cilia, and defects in intraflagellar t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf852b25959b60cd824224e1d1514dd4
https://hdl.handle.net/20.500.11820/fc4666bc-4ccd-4397-ac9d-b72e05904e0d
https://hdl.handle.net/20.500.11820/fc4666bc-4ccd-4397-ac9d-b72e05904e0d