Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Vera B. Schrauwen‐Hinderling"'
Autor:
Julian Mevenkamp, Yvonne M. H. Bruls, Rodrigo Mancilla, Lotte Grevendonk, Joachim E. Wildberger, Kim Brouwers, Matthijs K. C. Hesselink, Patrick Schrauwen, Joris Hoeks, Riekelt H. Houtkooper, Mijke Buitinga, Robin A. de Graaf, Lucas Lindeboom, Vera B. Schrauwen-Hinderling
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract NADH and NAD+ act as electron donors and acceptors and NAD+ was shown to stimulate mitochondrial biogenesis and metabolic health. We here develop a non-invasive Phosphorous Magnetic Resonance Spectroscopy (31P-MRS) method to quantify these m
Externí odkaz:
https://doaj.org/article/641cc9cbaffb4da5a60ddf4d1b9cf383
Autor:
Vera H. W. de Wit‑Verheggen, Sibel Altintas, Romy J. M. Spee, Casper Mihl, Sander M. J. van Kuijk, Joachim E. Wildberger, Vera B. Schrauwen‑Hinderling, Bas L. J. H. Kietselaer, Tineke van de Weijer
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/c091254015a04a97891ffda2b65361a0
Autor:
Vera H. W. de Wit-Verheggen, Vera B. Schrauwen-Hinderling, Kim Brouwers, Johanna A. Jörgensen, Gert Schaart, Anne Gemmink, Emmani B. M. Nascimento, Matthijs K. C. Hesselink, Joachim E. Wildberger, Patrique Segers, David Montaigne, Bart Staels, Patrick Schrauwen, Lucas Lindeboom, Joris Hoeks, Tineke van de Weijer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Cardiac energy status, measured as phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio with 31P-Magnetic Resonance Spectroscopy (31P-MRS) in vivo, is a prognostic factor in heart failure and is lowered in cardiometabolic disease. It has
Externí odkaz:
https://doaj.org/article/37b93e8a37d543e9a681f2a0a9782dad
Autor:
Rodrigo Mancilla, Diego Pava‐Mejia, Nynke vanPolanen, Vera deWit, Maaike Bergman, Lotte Grevendonk, Johanna Jorgensen, Esther Kornips, Joris Hoeks, Matthijs K. C. Hesselink, Vera B. Schrauwen‐Hinderling
Publikováno v:
Physiological Reports, Vol 11, Iss 12, Pp n/a-n/a (2023)
Abstract Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess skeletal muscle mitochondrial capacity, we tested how well different invasive and noninva
Externí odkaz:
https://doaj.org/article/e51d1203343b480098a2feb69c51dec1
Autor:
Froukje Vanweert, Michael Neinast, Edmundo Erazo Tapia, Tineke van de Weijer, Joris Hoeks, Vera B. Schrauwen-Hinderling, Megan C. Blair, Marc R. Bornstein, Matthijs K. C. Hesselink, Patrick Schrauwen, Zoltan Arany, Esther Phielix
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Evidence from preclinical models suggest that lowering levels of branched chain amino acids (BCAA) improves glucose metabolism. Here the authors report that NaPB, an accelerator of BCAA catabolism, improves peripheral insulin sensitivity in patients
Externí odkaz:
https://doaj.org/article/13e10d35d6bc4308a78288bcc1294944
Autor:
Cas J. Fuchs, Remco Kuipers, Jan A. Rombouts, Kim Brouwers, Vera B. Schrauwen-Hinderling, Joachim E. Wildberger, Lex B. Verdijk, Luc J.C. van Loon
Publikováno v:
Experimental Gerontology, Vol 175, Iss , Pp 112159- (2023)
Background: A key hallmark of aging is the progressive loss of skeletal muscle mass. Due to limitations of the various methods typically applied to assess muscle mass, only limited information is available on age-related differences between various m
Externí odkaz:
https://doaj.org/article/0b5c768ea39542baa026a61e08d67b32
Autor:
Karin J.C. Sanders, Roel Wierts, Wouter D. vanMarken Lichtenbelt, Judith deVos‐Geelen, Guy Plasqui, Marco C.J.M. Kelders, Vera B. Schrauwen‐Hinderling, Jan Bucerius, Anne‐Marie C. Dingemans, Felix M. Mottaghy, Annemie M.W.J. Schols
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1329-1338 (2022)
Abstract Background Brown adipose tissue (BAT) has been primarily researched as a potential target for mitigating obesity. However, the physiological significance of BAT in relation to cachexia remains poorly understood. The objective of this study w
Externí odkaz:
https://doaj.org/article/35ffa1b5ef564031b153d0b7b78edb68
Autor:
Yvo J.M. op den Kamp, Anne Gemmink, Marlies de Ligt, Bas Dautzenberg, Esther Kornips, Johanna A. Jorgensen, Gert Schaart, Russell Esterline, Diego A. Pava, Joris Hoeks, Vera B. Schrauwen-Hinderling, Sander Kersten, Bas Havekes, Timothy R. Koves, Deborah M. Muoio, Matthijs K.C. Hesselink, Jan Oscarsson, Esther Phielix, Patrick Schrauwen
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101620- (2022)
Objective: SGLT2 inhibitors increase urinary glucose excretion and have beneficial effects on cardiovascular and renal outcomes; the underlying mechanism may be metabolic adaptations due to urinary glucose loss. Here, we investigated the cellular and
Externí odkaz:
https://doaj.org/article/ce94ee3f45bd45f3ad7d1120c2287583
Autor:
Carlijn M. E. Remie, Michiel P. B. Moonen, Kay H. M. Roumans, Emmani B. M. Nascimento, Anne Gemmink, Bas Havekes, Gert Schaart, Esther Kornips, Peter J. Joris, Vera B. Schrauwen-Hinderling, Joris Hoeks, Sander Kersten, Matthijs K. C. Hesselink, Esther Phielix, Wouter D. van Marken Lichtenbelt, Patrick Schrauwen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Cold acclimation has been shown to have beneficial metabolic effects, including improved insulin sensitivity in patients with type 2 diabetes. Here the authors show that a mild cold acclimation regiment during which overt shivering was prevented did
Externí odkaz:
https://doaj.org/article/1c9d9177ddf8413ba3d5b7a5b26199f5
Autor:
Hans-F. Schött, Maurice C. J. M. Konings, Vera B. Schrauwen-Hinderling, Ronald P. Mensink, Jogchum Plat
Publikováno v:
ACS Omega, Vol 6, Iss 2, Pp 1129-1137 (2021)
Externí odkaz:
https://doaj.org/article/b448745adfcd4e0b8d32b4e5425015a0