Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Vera B, Plakhova"'
The monograph is a summary of methods used to study pain receptors and the results obtained in some experiments designed to study the effect of non-opioid analgesics. The molecular mechanisms of nociceptive information control in primary sensory noci
Autor:
Arina D. Kalinina, Ilya V. Rogachevskii, Dmitriy M. Samosvat, Georgy G. Zegrya, Irina P. Butkevich, Viktor A. Mikhailenko, Vera B. Plakhova, Valentina A. Penniyaynen, Svetlana A. Podzorova, Boris V. Krylov
Publikováno v:
Life, Vol 13, Iss 9, p 1800 (2023)
The present work continues our recent series of articles that aim to elucidate the ligand–receptor binding mechanism of short cationic peptides to the NaV1.8 channel in the nociceptive neuron. The applied methodological approach has involved severa
Externí odkaz:
https://doaj.org/article/a1b3eef0197d462281cf4dc46eae8528
Autor:
Ilya V. Rogachevskii, Dmitriy M. Samosvat, Valentina A. Penniyaynen, Vera B. Plakhova, Svetlana A. Podzorova, Ke Ma, Georgy G. Zegrya, Boris V. Krylov
Publikováno v:
Life, Vol 13, Iss 7, p 1500 (2023)
The signaling or non-pumping Na,K-ATPase function was first observed by us in the nociceptive neuron; Na,K-ATPase transduced the signals from the opioid-like receptors to NaV1.8 channels. This study elucidates the role of the rhamnosyl residue of oua
Externí odkaz:
https://doaj.org/article/0d52d25ceb894e7ea68472b2f7783147
Autor:
Vera B. Plakhova, Dmitriy M. Samosvat, Georgy G. Zegrya, Valentina A. Penniyaynen, Arina D. Kalinina, Ma Ke, Svetlana A. Podzorova, Boris V. Krylov, Ilya V. Rogachevskii
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10640 (2022)
Several arginine-containing short peptides have been shown by the patch-clamp method to effectively modulate the NaV1.8 channel activation gating system, which makes them promising candidates for the role of a novel analgesic medicinal substance. As
Externí odkaz:
https://doaj.org/article/430cf54f5f414380a3011ff5e306cc50
Autor:
Ilya V. Rogachevskii, Vera B. Plakhova, Valentina A. Penniyaynen, Arina D. Kalinina, Svetlana A. Podzorova, Dmitriy M. Samosvat, Georgy G. Zegrya, Boris V. Krylov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5993 (2022)
Two short arginine-containing tripeptides, H-Arg-Arg-Arg-OH (TP1) and Ac-Arg-Arg-Arg-NH2 (TP2), have been shown by the patch-clamp method to modulate the NaV1.8 channels of DRG primary sensory neurons, which are responsible for the generation of noci
Externí odkaz:
https://doaj.org/article/8c4396cdb3c44f7292c9d4abb4e44966
Autor:
Krylov, Ilya V. Rogachevskii, Dmitriy M. Samosvat, Valentina A. Penniyaynen, Vera B. Plakhova, Svetlana A. Podzorova, Ke Ma, Georgy G. Zegrya, Boris V.
Publikováno v:
Life; Volume 13; Issue 7; Pages: 1500
The signaling or non-pumping Na,K-ATPase function was first observed by us in the nociceptive neuron; Na,K-ATPase transduced the signals from the opioid-like receptors to NaV1.8 channels. This study elucidates the role of the rhamnosyl residue of oua
Autor:
Ilya V. Rogachevskii, Dmitriy M. Samosvat, Arina D. Kalinina, Georgiy G. Zegrya, Boris V. Krylov, Svetlana A. Podzorova, Vera B. Plakhova
Publikováno v:
Integrative Physiology. 2:412-419
Autor:
Vera B, Plakhova, Valentina A, Penniyaynen, Ilia V, Rogachevskii, Svetlana A, Podzorova, Maksim M, Khalisov, Alexander V, Ankudinov, Boris V, Krylov
Publikováno v:
Canadian journal of physiology and pharmacology. 98(11)
In the primary sensory neuron, ouabain activates the dual mechanism that modulates the functional activity of Na
Publikováno v:
Frontiers in Pain Science. :127-182
Publikováno v:
Frontiers in Pain Science. :3-61