Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vera, Rötzer"'
Autor:
Daniela Kugelmann, Vera Rötzer, Elias Walter, Desalegn Tadesse Egu, Michael Tobias Fuchs, Franziska Vielmuth, Hilda Vargas-Robles, Michael Schnoor, Michael Hertl, Rüdiger Eming, Klemens Rottner, Ansgar Schmidt, Volker Spindler, Jens Waschke
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoantibodies against desmoglein (Dsg) 1 and Dsg3 primarily cause blister formation in the autoimmune disease pemphigus vulgaris (PV). Src was proposed to contribute to loss of keratinocyte cohesion. However, the role and underlying mechanisms are u
Externí odkaz:
https://doaj.org/article/ebacc96b80ad43a2a0d3b919c2e0a6d9
Autor:
Ingrid, Zahn, Fabian, Garreis, Martin, Schicht, Vera, Rötzer, Jens, Waschke, Yuqiuhe, Liu, Valerian L, Altersberger, Friedrich, Paulsen, Jana, Dietrich
Publikováno v:
International journal of molecular sciences. 23(23)
The meibomian glands (MGs) within the eyelids produce a lipid-rich secretion that forms the superficial layer of the tear film. Meibomian gland dysfunction (MGD) results in excessive evaporation of the tear film, which is the leading cause of dry eye
Publikováno v:
The American Journal of Pathology. 189:1559-1568
Meibomian glands within the eyelid are important for the maintenance of the integrity and health of the ocular surface. Patients with the blistering skin disease pemphigus vulgaris (PV), which is caused by autoantibodies against desmosomal cadherins,
Autor:
Vera Rötzer, Markus E. Diefenbacher, Nicolas Schlegel, Hanna Ungewiß, Christina Fey, Michael Meir, Jens Waschke
Publikováno v:
Cellular and Molecular Life Sciences. 75:4251-4268
Rapidly renewing epithelial tissues such as the intestinal epithelium require precise tuning of intercellular adhesion and proliferation to preserve barrier integrity. Here, we provide evidence that desmoglein 2 (Dsg2), an adhesion molecule of desmos
Autor:
Marie-Therès Wanuske, Franziska Vielmuth, Vera Rötzer, Matthias Hiermaier, Nicole Endlich, Chiara Stüdle, Felix Kliewe, I. Piotr Maly, Camilla Schinner, Volker Spindler, Jens Waschke
Intercellular adhesion is essential for tissue integrity and homeostasis. Desmosomes are especially abundant in the epidermis and the myocardium, tissues, which are under constantly changing mechanical stresses. Yet, it is largely unclear whether des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c920b871f0df1af017a9f700a9ad3d86
https://doi.org/10.1101/787846
https://doi.org/10.1101/787846
Autor:
Sebastian Kant, Vera Rötzer, Angela Schlipp, Ellen Kempf, Thomas D. Mueller, Camilla Schinner, Jens Waschke, Bernd Erber, Sunil Yeruva, Rudolf E. Leube
Publikováno v:
JCI Insight
Arrhythmogenic cardiomyopathy (AC) is a genetic disease causing arrhythmia and sudden cardiac death with only symptomatic therapy available at present. Mutations of desmosomal proteins, including desmoglein-2 (Dsg2) and plakoglobin (Pg), are the majo
Autor:
Vera Rötzer, Franziska Vielmuth, Michael Hertl, Hilda Vargas-Robles, Volker Spindler, Daniela Kugelmann, Jens Waschke, Klemens Rottner, Michael Schnoor, Elias Walter, Desalegn Tadesse Egu
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Histochemistry and Cell Biology. 146:685-694
Meibomian glands are a modified type of sebaceous glands within the eye lid, which produce an oily secretion important for the stabilization and the prevention of evaporation of the tear film. The holocrine secretory mode of Meibomian glands is chara
Autor:
Jens Waschke, Eva Hartlieb, Angela Schlipp, Miklós Sárdy, Volker Spindler, Julia Winkler, Vera Rötzer, Elias Walter
Publikováno v:
Journal of Investigative Dermatology. 136(1):301-310
The desmosomal transmembrane adhesion molecules desmoglein 3 (Dsg3) and desmocollin 3 (Dsc3) are required for strong keratinocyte cohesion. Recently, we have shown that Dsg3 associates with p38 mitogen-activated protein kinase (p38MAPK) and suppresse
Publikováno v:
Cellular and Molecular Life Sciences. 72:4885-4897
Desmosomes provide strong intercellular cohesion essential for the integrity of cells and tissues exposed to continuous mechanical stress. For desmosome assembly, constitutively synthesized desmosomal cadherins translocate to the cell-cell border, cl