Purified human anti-Tn and anti-T antibodies specifically recognize carcinoma tissues

Autor: Ricardo D. Lardone, Yohana Camila Garay, Fernando J. Irazoqui, Verónica Maria Grupe, Natacha Zlocowski, Gustavo A. Nores

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Described in several epithelial cancer cells, Tn- (GalNAcα1-O-Ser/Thr) and T- (Galβ3GalNAcα1-O-Ser/Thr) antigens are examples of tumor-associated antigens. Increased expression of Tn- and T-antigens is associated with tumor invasion and metastasis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d687393f23c8caaaf4b2e6e0a6fd1406
https://pubmed.ncbi.nlm.nih.gov/31147593