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pro vyhledávání: '"Verònica Ventura"'
Publikováno v:
Drug Metabolism and Disposition. 40:1268-1278
Irosustat is a first-generation, irreversible, steroid sulfatase inhibitor currently in development for hormone-dependent cancer therapy. To predict clinical drug-drug interactions between irosustat and possible concomitantly administered medications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2595875a2774f0a5cae9ebf82f487d
https://doi.org/10.1124/dmd.111.044271
https://doi.org/10.1124/dmd.111.044271
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 39(7)
Irosustat is a novel steroid sulfatase inhibitor for hormone-dependent cancer therapy. Its structure is a tricyclic coumarin-based sulfamate that undergoes desulfamoylation in aqueous solution, yielding the sulfamoyl-free derivative, 667-coumarin. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e591f1130d9d689b09fd3e85ab5579d2
https://pubmed.ncbi.nlm.nih.gov/21464173
https://pubmed.ncbi.nlm.nih.gov/21464173
Autor:
Marcos Pintos, Verónica Ventura, Maximiliano Tarallo, Daniel Rienzi, Jorge Decaro, Mario Cancela
Publikováno v:
Revista Médica del Uruguay, Vol 33, Iss 4, Pp 249-53 (2019)
Para pacientes que sufren artrosis avanzada o en algunos casos de fractura de cadera, la solución quirúrgica que se propone es la cirugía ortopédica mayor. Alguno de estos pacientes requerirá transfusión de sangre o hemocomponentes, o ambos, an
Externí odkaz:
https://doaj.org/article/8c928e8ac9cc48b3b5cb7e9b5da23c4e
Akademický článek
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Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (3):375-382
GSK3beta and E2F1 play an important role in the control of proliferation and apoptosis. Previous work has demonstrated that GSK3beta indirectly regulates E2F activity through modulation of cyclin D1 levels. In this work we show that GSK3beta phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b2a90cfdeff0953e4d855db690d02b