Zobrazeno 1 - 10
of 696
pro vyhledávání: '"Ventromedial nucleus of the hypothalamus"'
Publikováno v:
Life, Vol 10, Iss 4, p 48 (2020)
Maternal obesity during pregnancy is associated with a greater risk of poor health outcomes in offspring, including obesity, metabolic disorders, and anxiety, however the incidence of these diseases differs for males and females. Similarly, animal mo
Externí odkaz:
https://doaj.org/article/231350f67dfe4be9bfdef6e2dc550105
Autor:
Liliana Perdomo, Begoña Porteiro, Patricia Mallegol, Marcos Rios Garcia, Grégory Hilairet, Ismael González-García, Ramón Iglesias-Rey, Kamal Rahmouni, Verónica Rivas-Limeres, Jens Mittag, Cristina Contreras, Anxo Vidal, Donald A. Morgan, Rubén Nogueiras, Juan Carlos Roa, Ramaroson Andriantsitohaina, Edward Milbank, Manuel Tena-Sempere, Carlos Dieguez, Rebecca Oelkrug, Francesc Villarroya, Francisco Ruiz-Pino, Nathalia Romanelli Vicente Dragano, Juan Cuñarro, Miguel López, Aleix Gavaldà-Navarro, Luisa Vergori, Tomás Sobrino, Cristina García-Cáceres, M. Carmen Martinez
Publikováno v:
Nat. Metab. 3, 1415-1431 (2021)
Current pharmacological therapies for treating obesity are of limited efficacy. Genetic ablation or loss of function of AMP-activated protein kinase alpha 1 (AMPKα1) in steroidogenic factor 1 (SF1) neurons of the ventromedial nucleus of the hypothal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8fb87d6d344691ef77369cdd0a257d
https://doi.org/10.1038/s42255-021-00467-8
https://doi.org/10.1038/s42255-021-00467-8
Publikováno v:
Neuropsychopharmacology Reports
Aims Electroconvulsive seizure (ECS) therapy is highly effective in the treatment of several psychiatric disorders, including depression. Past studies have shown that the rodent model of ECS reveals the activation of multiple brain regions including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba45c2a7ff33ef8783f3a4a4cb9de931
https://doi.org/10.1002/npr2.12156
https://doi.org/10.1002/npr2.12156
Autor:
Simon M. Luckman, Tansi Khodai
Publikováno v:
Endocrinology
The ventromedial nucleus of the hypothalamus (VMH) is a complex brain structure that is integral to many neuroendocrine functions, including glucose regulation, thermogenesis, and appetitive, social, and sexual behaviors. As such, it is of little sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19363b62ad649e8944219287cc1d0bf
https://doi.org/10.1210/endocr/bqab141
https://doi.org/10.1210/endocr/bqab141
Publikováno v:
J Neuroendocrinol
Paternal absence can significantly alter bio-behavioural development in many biparental species. This effect has generally been demonstrated by comparing the development of offspring reared under biparental care with those reared by a single mother.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ecbc4346276986e285c71ad0755d61
https://doi.org/10.1111/jne.13001
https://doi.org/10.1111/jne.13001
Autor:
Ruth B. S. Harris
Publikováno v:
Am J Physiol Endocrinol Metab
This experiment investigated which hypothalamic nuclei were activated by a dose of leptin that inhibited food intake. Foodnot intake, energy expenditure, respiratory exchange ratio (RER), and intrascapular brown adipose tissue (IBAT) temperature were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd42c93b45880cdd6ac20b6dd8d98ef
https://doi.org/10.1152/ajpendo.00143.2021
https://doi.org/10.1152/ajpendo.00143.2021
Autor:
Angelo Cignarelli, Valentina Annamaria Genchi, Luigi Laviola, Francesco Giorgino, Sebastio Perrini, Cristina Caccioppoli, Rossella Doria, Annalisa Natalicchio, Giuseppe De Palma
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6445, p 6445 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Leptin is a principal adipose-derived hormone mostly implicated in the regulation of energy balance through the activation of anorexigenic neuronal pathways. Comprehensive studies have established that the maintenance of certain concentrations of cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e516b6120110c05bb1e1efe0cd6aebf9
https://www.mdpi.com/1422-0067/22/12/6445
https://www.mdpi.com/1422-0067/22/12/6445
Publikováno v:
Am J Physiol Endocrinol Metab
Leptin administration into the hindbrain, and specifically the nucleus of the solitary tract, increases phosphorylated signal transducer and activator of transcription 3 (pSTAT3), a marker of leptin receptor activation, in hypothalamic nuclei known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a8f5aad6054edc784fe8c34a951206
https://doi.org/10.1152/ajpendo.00205.2019
https://doi.org/10.1152/ajpendo.00205.2019
Autor:
Seraina S. Senn, Christina N. Boyle, Lynda Whiting, Sonya Duffy, Christelle Le Foll, Erika Tarasco, Thomas A. Lutz
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 317:R451-R460
Leptin receptor (LepR) signaling in neurons of the ventromedial nucleus of the hypothalamus (VMH), specifically those expressing steroidogenic factor-1 (SF1), have been proposed to play a key role in controlling energy balance. By crossing LepR-silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e689780955a16313f165ba69f72f5f7
https://doi.org/10.1152/ajpregu.00111.2019
https://doi.org/10.1152/ajpregu.00111.2019
Publikováno v:
Behavioural Brain Research. 367:128-142
Estrogens receptors (ER) are involved in several sociosexual behaviors and fear responses. In particular, the ERα is important for sexual behaviors, whereas ERβ modulates anxiolytic responses. Using shRNA directed either against the ERα or the ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b228ea50fd85773c0d849494d10260
https://doi.org/10.1016/j.bbr.2019.03.045
https://doi.org/10.1016/j.bbr.2019.03.045