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Spiro and Dispiro-1,2,4-trioxolanes as Antimalarial Peroxides:  Charting a Workable Structure−Activity Relationship Using Simple Prototypes

Autor: Dong, Y., Chollet, J., Matile, H., Charman, S. A., Chiu, F. C. K., Charman, W. N., Scorneaux, B., Urwyler, H., Tomas, J. Santo, Scheurer, C., Snyder, C., Dorn, A., Wang, X., Karle, J. M., Tang, Y., Wittlin, S., Brun, R., Vennerstrom, J. L.

Publikováno v: Journal of Medicinal Chemistry; July 2005, Vol. 48 Issue: 15 p4953-4961, 9p

A 3D QSAR Pharmacophore Model and Quantum Chemical Structure−Activity Analysis of Chloroquine(CQ)-Resistance Reversal

Autor: Bhattacharjee, A. K., Kyle, D. E., Vennerstrom, J. L., Milhous, W. K.

Publikováno v: Journal of Chemical Information and Computer Sciences (now called Journal of Chemical Information and Modeling); September 2002, Vol. 42 Issue: 5 p1212-1220, 9p

Methyl-Substituted Dispiro-1,2,4,5-tetraoxanes:  Correlations of Structural Studies with Antimalarial Activity

Autor: McCullough, K. J., Wood, J. K., Bhattacharjee, A. K., Dong, Y., Kyle, D. E., Milhous, W. K., Vennerstrom, J. L.

Publikováno v: Journal of Medicinal Chemistry; March 23, 2000, Vol. 43 Issue: 6 p1246-1249, 4p

Synthesis and Antimalarial Activity of 11 Dispiro-1,2,4,5-tetraoxane Analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes Substituted at the 1 and 10 Positions with Unsaturated and Polar Functional Groups

Autor: Dong, Y., Matile, H., Chollet, J., Kaminsky, R., Wood, J. K., Vennerstrom, J. L.

Publikováno v: Journal of Medicinal Chemistry; April 1999, Vol. 42 Issue: 8 p1477-1480, 4p