Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Venky, Soundararajan"'
Autor:
Pritha Ghosh, Michiel J.M. Niesen, Colin Pawlowski, Hari Bandi, Unice Yoo, Patrick J. Lenehan, Praveen Kumar-M, Mihika Nadig, Jason Ross, Sankar Ardhanari, John C. O’Horo, A.J. Venkatakrishnan, Clifford J. Rosen, Amalio Telenti, Ryan T. Hurt, Venky Soundararajan
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110406- (2024)
Summary: Post-COVID-19 conditions (long COVID) has impacted many individuals, yet risk factors for this condition are poorly understood. This retrospective analysis of 88,943 COVID-19 patients at a multi-state US health system compares phenotypes, la
Externí odkaz:
https://doaj.org/article/b2d8fbdc7a5f43fba95558d1d6f2dccf
Autor:
Samir Awasthi, Nikhil Sachdeva, Yash Gupta, Ausath G. Anto, Shahir Asfahan, Ruben Abbou, Sairam Bade, Sanyam Sood, Lars Hegstrom, Nirupama Vellanki, Heather M. Alger, Melwin Babu, Jose R. Medina-Inojosa, Robert B. McCully, Amir Lerman, Mark Stampehl, Rakesh Barve, Zachi I. Attia, Paul A. Friedman, Venky Soundararajan, Francisco Lopez-Jimenez
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102259- (2023)
Summary: Background: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death worldwide, driven primarily by coronary artery disease (CAD). ASCVD risk estimators such as the pooled cohort equations (PCE) facilitate risk stratifica
Externí odkaz:
https://doaj.org/article/97d6bc637a9f484f91ae2a92cbf0ea4a
Autor:
A. J. Venkatakrishnan, Praveen Anand, Patrick J. Lenehan, Pritha Ghosh, Rohit Suratekar, Eli Silvert, Colin Pawlowski, Abhishek Siroha, Dibyendu Roy Chowdhury, John C. O’Horo, Joseph D. Yao, Bobbi S. Pritt, Andrew P. Norgan, Ryan T. Hurt, Andrew D. Badley, John Halamka, Venky Soundararajan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The emergence of highly transmissible SARS-CoV-2 variants and vaccine breakthrough infections globally mandated the characterization of the immuno-evasive features of SARS-CoV-2. Here, we systematically analyzed 2.13 million SARS-CoV-2 genom
Externí odkaz:
https://doaj.org/article/fba33ff5aa224b2f947ad65933a846dd
Autor:
Robert P Matson, BS, Michiel J M Niesen, PhD, Emily R Levy, MD, Derek N Opp, DO, Patrick J Lenehan, PhD, Greg Donadio, MA, John C O'Horo, ProfMD, A J Venkatakrishnan, PhD, Andrew D Badley, ProfMD, Venky Soundararajan, PhD
Publikováno v:
The Lancet: Digital Health, Vol 5, Iss 4, Pp e206-e216 (2023)
Summary: Background: The emergency use authorisation of BNT162b2 (tozinameran; Comirnaty, Pfizer–BioNTech) for children aged 5–17 years has resulted in rapid vaccination in the paediatric population. However, there are few studies of adverse even
Externí odkaz:
https://doaj.org/article/7a5fc9eade034d6dad7d93a8c05949a9
Autor:
Praveen Anand, Patrick J. Lenehan, Michiel Niesen, Unice Yoo, Dhruti Patwardhan, Marcelo Montorzi, A. J. Venkatakrishnan, Venky Soundararajan
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Acute cardiac injury has been observed in a subset of COVID-19 patients, but the molecular basis for this clinical phenotype is unknown. It has been hypothesized that molecular mimicry may play a role in triggering an autoimmune inflammatory
Externí odkaz:
https://doaj.org/article/418d444ed33943be9dcd88ee418c74b9
Autor:
Rohit Suratekar, Pritha Ghosh, Michiel J M Niesen, Gregory Donadio, Praveen Anand, Venky Soundararajan, A J Venkatakrishnan
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 2, Pp 1-10 (2022)
Abstract The highly contagious Delta variant of SARS‐CoV‐2 has become a prevalent strain globally and poses a public health challenge around the world. While there has been extensive focus on understanding the amino acid mutations in the Delta va
Externí odkaz:
https://doaj.org/article/2cc1e88e04c54521bcb418b729fd04e2
Mapping each pre-existing condition’s association to short-term and long-term COVID-19 complications
Autor:
A. J. Venkatakrishnan, Colin Pawlowski, David Zemmour, Travis Hughes, Akash Anand, Gabriela Berner, Nikhil Kayal, Arjun Puranik, Ian Conrad, Sairam Bade, Rakesh Barve, Purushottam Sinha, John C. O‘Horo, Andrew D. Badley, John Halamka, Venky Soundararajan
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-11 (2021)
Abstract Understanding the relationships between pre-existing conditions and complications of COVID-19 infection is critical to identifying which patients will develop severe disease. Here, we leverage ~1.1 million clinical notes from 1803 hospitaliz
Externí odkaz:
https://doaj.org/article/5d3be4022eee45a2a9e665e11457f771
Autor:
Samir Awasthi, Tyler Wagner, A. J. Venkatakrishnan, Arjun Puranik, Matthew Hurchik, Vineet Agarwal, Ian Conrad, Christian Kirkup, Raman Arunachalam, John O’Horo, Walter Kremers, Rahul Kashyap, William Morice, John Halamka, Amy W. Williams, William A. Faubion, Andrew D. Badley, Gregory J. Gores, Venky Soundararajan
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Intensive care unit (ICU) admissions and mortality in severe COVID-19 patients are driven by “cytokine storms” and acute respiratory distress syndrome (ARDS). Interim clinical trial results suggest that the corticosteroid dexamethasone d
Externí odkaz:
https://doaj.org/article/21d3d722d5694b8e826ba15f02943128
Autor:
Colin Pawlowski, Arjun Puranik, Hari Bandi, A. J. Venkatakrishnan, Vineet Agarwal, Richard Kennedy, John C. O’Horo, Gregory J. Gores, Amy W. Williams, John Halamka, Andrew D. Badley, Venky Soundararajan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Clinical studies are ongoing to assess whether existing vaccines may afford protection against SARS-CoV-2 infection through trained immunity. In this exploratory study, we analyze immunization records from 137,037 individuals who received SA
Externí odkaz:
https://doaj.org/article/fd67bc36356140aaa170bb2c2ae1d4bb
Autor:
A. J. Venkatakrishnan, Praveen Anand, Patrick J. Lenehan, Rohit Suratekar, Bharathwaj Raghunathan, Michiel J. M. Niesen, Venky Soundararajan
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1509 (2022)
The emergence of a heavily mutated SARS-CoV-2 variant (Omicron; Pango lineage B.1.1.529 and BA sublineages) and its rapid spread to over 75 countries raised a global public health alarm. Characterizing the mutational profile of Omicron is necessary t
Externí odkaz:
https://doaj.org/article/01f279759ae34afabfeab79abb059894