Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Venkatraman E, Seshan"'
Autor:
Ryan N. Ptashkin, Mark D. Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S. Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova-Drus, Abhinita S. Mohanty, Ruben Bacares, Jamal Benhamida, Satshil Rana, Anna Razumova, Chad Vanderbilt, Anoop Balakrishnan Rema, Ivelise Rijo, Julie Son-Garcia, Ino de Bruijn, Menglei Zhu, Sean Lachhander, Wei Wang, Mohammad S. Haque, Venkatraman E. Seshan, Jiajing Wang, Ying Liu, Khedoudja Nafa, Laetitia Borsu, Yanming Zhang, Umut Aypar, Sarah P. Suehnholz, Debyani Chakravarty, Jae H. Park, Omar Abdel-Wahab, Anthony R. Mato, Wenbin Xiao, Mikhail Roshal, Mariko Yabe, Connie Lee Batlevi, Sergio Giralt, Gilles Salles, Raajit Rampal, Martin Tallman, Eytan M. Stein, Anas Younes, Ross L. Levine, Miguel-Angel Perales, Marcel R. M. van den Brink, Ahmet Dogan, Marc Ladanyi, Michael F. Berger, A. Rose Brannon, Ryma Benayed, Ahmet Zehir, Maria E. Arcila
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Genomic profiling of hematologic malignancies has augmented our understanding of variants that contribute to disease pathogenesis and supported development of prognostic models that inform disease management in the clinic. Tumor only sequenc
Externí odkaz:
https://doaj.org/article/59810dc4afb84879a7847ea6b19a947d
Autor:
Fushen Sha, Michelle Okwali, Anna Alperovich, Philip C. Caron, Lorenzo Falchi, Audrey Hamilton, Paul A. Hamlin, Steven M. Horwitz, Erel Joffe, Niloufer Khan, Anita Kumar, Matthew J. Matasar, Alison J. Moskowitz, Ariela Noy, Colette Owens, Lia M. Palomba, Ildefonso Rodriguez-Rivera, David Straus, Gottfried von Keudell, Andrew D. Zelenetz, Joachim Yahalom, Ahmet Dogan, Heiko Schöder, Venkatraman E. Seshan, Gilles Salles, Anas Younes, Connie L. Batlevi
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 2, Pp 1-9 (2022)
Abstract Between 1998 and 2009, a total of 295 patients (median age 58, 53% females) with newly diagnosed early-stage follicular lymphoma (FL) were managed at Memorial Sloan Kettering Cancer Center. Approximately half of patients (137, 46%) underwent
Externí odkaz:
https://doaj.org/article/50c12e5101aa448db50c1d686239c9d6
Autor:
Sabela Bobillo, Erel Joffe, David Sermer, Patrizia Mondello, Paola Ghione, Philip C. Caron, Audrey Hamilton, Paul A. Hamlin, Steven M. Horwitz, Anita Kumar, Matthew J. Matasar, Connie L. Batlevi, Alison Moskowitz, Ariela Noy, Collette N. Owens, M. Lia Palomba, David Straus, Gottfried von Keudell, Ahmet Dogan, Andrew D. Zelenetz, Venkatraman E. Seshan, Anas Younes
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-6 (2021)
Abstract Although methotrexate (MTX) is the most widely used therapy for central nervous system (CNS) prophylaxis in patients with diffuse large B-cell lymphoma (DLBCL), the optimal regimen remains unclear. We examined the efficacy of different proph
Externí odkaz:
https://doaj.org/article/da2cd3491fa94fc7a249c5f39c64ee22
Autor:
Dana W. Y. Tsui, Michael L. Cheng, Maha Shady, Julie L. Yang, Dennis Stephens, Helen Won, Preethi Srinivasan, Kety Huberman, Fanli Meng, Xiaohong Jing, Juber Patel, Maysun Hasan, Ian Johnson, Erika Gedvilaite, Brian Houck-Loomis, Nicholas D. Socci, S. Duygu Selcuklu, Venkatraman E. Seshan, Hongxin Zhang, Debyani Chakravarty, Ahmet Zehir, Ryma Benayed, Maria Arcila, Marc Ladanyi, Samuel A. Funt, Darren R. Feldman, Bob T. Li, Pedram Razavi, Jonathan Rosenberg, Dean Bajorin, Gopa Iyer, Wassim Abida, Howard I. Scher, Dana Rathkopf, Agnes Viale, Michael F. Berger, David B. Solit
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Cell-free DNA (cfDNA) profiling is increasingly used to guide cancer care, yet mutations are not always identified. The ability to detect somatic mutations in plasma depends on both assay sensitivity and the fraction of circulatin
Externí odkaz:
https://doaj.org/article/a175329a098b4151983ca7a727781ce0
Autor:
Cristina Valero, Mark Lee, Douglas Hoen, Kate Weiss, Daniel W. Kelly, Prasad S. Adusumilli, Paul K. Paik, George Plitas, Marc Ladanyi, Michael A. Postow, Charlotte E. Ariyan, Alexander N. Shoushtari, Vinod P. Balachandran, A. Ari Hakimi, Aimee M. Crago, Kara C. Long Roche, J. Joshua Smith, Ian Ganly, Richard J. Wong, Snehal G. Patel, Jatin P. Shah, Nancy Y. Lee, Nadeem Riaz, Jingming Wang, Ahmet Zehir, Michael F. Berger, Timothy A. Chan, Venkatraman E. Seshan, Luc G. T. Morris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
There is an unmet clinical need for simple, accessible biomarkers to select patients who are more likely to respond to immune checkpoint therapy. Here the authors show that a lower neutrophil-to-lymphocyte ratio is associated with better overall and
Externí odkaz:
https://doaj.org/article/dd218269962540ee8add1e4fa781b7e2
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-13 (2020)
Abstract Background Comprehensive molecular profiling has revealed somatic variations in cancer at genomic, epigenomic, transcriptomic, and proteomic levels. The accumulating data has shown clearly that molecular phenotypes of cancer are complex and
Externí odkaz:
https://doaj.org/article/32673e97b6b540039b376a51bdf57fc8
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background We previously introduced a random-effects model to analyze a set of patients, each of which has two distinct tumors. The goal is to estimate the proportion of patients for which one of the tumors is a metastasis of the other, i.e.
Externí odkaz:
https://doaj.org/article/28636b07808e425089dd12c9228c0c8b
Autor:
Sarah Kishinevsky, Tai Wang, Anna Rodina, Sun Young Chung, Chao Xu, John Philip, Tony Taldone, Suhasini Joshi, Mary L. Alpaugh, Alexander Bolaender, Simon Gutbier, Davinder Sandhu, Faranak Fattahi, Bastian Zimmer, Smit K. Shah, Elizabeth Chang, Carmen Inda, John Koren, Nathalie G. Saurat, Marcel Leist, Steven S. Gross, Venkatraman E. Seshan, Christine Klein, Mark J. Tomishima, Hediye Erdjument-Bromage, Thomas A. Neubert, Ronald C. Henrickson, Gabriela Chiosis, Lorenz Studer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The early molecular events that ultimately lead to neuronal cell death in pathologies such as Parkinson’s disease are poorly understood. Here the authors use pluripotent stem-cell-derived human midbrain neurons and chemical biology tools to gain mo
Externí odkaz:
https://doaj.org/article/58327b67c3514927a9a253f4bd3c8f1f
Autor:
Barry S. Taylor, Hikmat A. Al-Ahmadie, David B. Solit, Gopa Iyer, Michael F. Berger, Nikolaus Schultz, Dean F. Bajorin, Jonathan E. Rosenberg, Bernard H. Bochner, Charles M. Rudin, Victor E. Reuter, Xueli Hao, Eugene K. Cha, Agnes Viale, Adam Abeshouse, Ritika Kundra, Venkatraman E. Seshan, Ronglai Shen, Nicholas D. Socci, Neil B. Desai, Alexander Penson, Matthew T. Chang
Supplementary Figure 2: Enrichment of biallelic RB1 in SCCBs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ce3613ff5239cdca6e4f648fcc5938
https://doi.org/10.1158/1078-0432.22465017.v1
https://doi.org/10.1158/1078-0432.22465017.v1
Autor:
Owen A. O'Connor, Pier Luigi Zinzani, Jasmine M. Zain, Venkatraman E. Seshan, Luigi Scotto, Luca Paoluzzi, Enrica Marchi
Purpose: Pralatrexate (10-propargyl-10-deazaaminopterin) is an antifolate with improved cellular uptake and retention due to greater affinity for the reduced folate carrier (RFC-1) and folyl-polyglutamyl synthase. Based on the PROPEL data, pralatrexa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b83988d4f8c06d2496f6985339cdb10
https://doi.org/10.1158/1078-0432.c.6519545.v1
https://doi.org/10.1158/1078-0432.c.6519545.v1