Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Venkatram R. Atigadda"'
Autor:
Olga V. Belyaeva, Alla V. Klyuyeva, Ansh Vyas, Wilhelm K. Berger, Laszlo Halasz, Jianshi Yu, Venkatram R. Atigadda, Aja Slay, Kelli R. Goggans, Matthew B. Renfrow, Maureen A. Kane, Laszlo Nagy, Natalia Y. Kedishvili
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/fe3e1010095d44f79e85b4d5d378ad56
Autor:
Adele P. Williams, Evan F. Garner, Laura L. Stafman, Jamie M. Aye, Colin H. Quinn, Raoud Marayati, Jerry E. Stewart, Venkatram R. Atigadda, Elizabeth Mroczek-Musulman, Blake P. Moore, Elizabeth A. Beierle, Gregory K. Friedman
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1364-1374 (2019)
PURPOSE: In spite of advances in therapy for some subtypes, group 3 medulloblastoma continues to portend a poor prognosis. A subpopulation of medulloblastoma cells expressing the cell surface marker CD133 have been posited as possible stem cell like
Externí odkaz:
https://doaj.org/article/798dcfd1d04e44b4aa17ab1120ac63b9
Autor:
Venkatram R. Atigadda, Mahendra P. Kashyap, Zhengrong Yang, Debasish Chattopadhyay, Nathalia Melo, Rajesh Sinha, Olga V. Belyaeva, Chu-Fang Chou, Pi-Ling Chang, Natalia Y. Kedishvili, Clinton J. Grubbs, Matthew B. Renfrow, Donald D. Muccio, Craig A. Elmets, Mohammad Athar
Publikováno v:
J Med Chem
Compound 1 is a potent rexinoid that is highly effective in cancer chemoprevention but elevates serum triglycerides. In an effort to separate the lipid toxicity from the anticancer activity of 1, we synthesized four new analogs of rexinoid 1, of whic
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Figure S1 / S2. UAB30 activated caspase 3. Figure S3. UAB30 increased nestin protein. Figure S4 / S5. UAB30 decreased neuroblastoma cellular proliferation. Figure S6 / S7. UAB30 did not alter expression or phosphorylation of ERK1/2 or AKT. Figure S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eec685733995105952fb1722e984eab
https://doi.org/10.1158/1535-7163.22501552.v1
https://doi.org/10.1158/1535-7163.22501552.v1
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Neuroblastoma remains a common cause of pediatric cancer deaths, especially for children who present with advanced stage or recurrent disease. Currently, retinoic acid therapy is used as maintenance treatment to induce differentiation and reduce tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348dc350f3894592ab83c27de40a958f
https://doi.org/10.1158/1535-7163.c.6536827.v1
https://doi.org/10.1158/1535-7163.c.6536827.v1
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Representative photomicrographs of G401 cells stained for total RXR (red) and nucleus (DAPI, blue) showed increased overlap after UAB30 treatment (merged, bottom right panel) indicating increased RXR staining in the nucleus following UAB30 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90e1c915e3151ca1804658caf4c5644
https://doi.org/10.1158/1535-7163.22508349.v1
https://doi.org/10.1158/1535-7163.22508349.v1
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Cellular proliferation was measured with trypan blue exclusion. Cell lines were treated with UAB30 at 0 or 10 μM for 24 hrs. Cells were stained with trypan blue and counted with a hemacytometer. A The total number of cells decreased in all 3 cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b50f9f9e20fbcc372b8f6168f23d0b
https://doi.org/10.1158/1535-7163.22508343
https://doi.org/10.1158/1535-7163.22508343
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
Legends for the supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e40f3fc502b667958d8a6d55dcc9159
https://doi.org/10.1158/1535-7163.22508352
https://doi.org/10.1158/1535-7163.22508352
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
The effects of UAB30 upon the expression and phosphorylation of kinases involved in cellular survival and apoptosis were evaluated with immunoblotting. Cells were treated with UAB30 (10 µM) and whole cell lysates were examined with immunoblotting fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b17dfc51951778bfab70e3980655b1
https://doi.org/10.1158/1535-7163.22508331
https://doi.org/10.1158/1535-7163.22508331
Autor:
Elizabeth A. Beierle, Clinton J. Grubbs, Donald D. Muccio, Elizabeth Mroczek-Musulman, Venkatram R. Atigadda, Jerry E. Stewart, Alicia M. Waters
In the SK-NEP-1 in vivo experiments, the animals fed UAB30 chow, although healthy throughout the experiment, gained weight at a slower rate than animals fed vehicle-treated chow. To demonstrate that the smaller size did not affect the tumor volumes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ddbedc4e8f640f7a52d1c4eaae4ac3
https://doi.org/10.1158/1535-7163.22508337.v1
https://doi.org/10.1158/1535-7163.22508337.v1