Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Venkatram, Atigadda"'
Autor:
Mary L Disis, Sasha E Stanton, Shizuko Sei, Lauren Corulli, Rodmaker Erin, Nicholas Drovetto, Venkatram Atigadda, Clinton Grubbs
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1b80aa6bf0b3469bb9cb1a41e6e41c1e
Autor:
Lin Jin, Mahendra P. Kashyap, Yunjia Chen, Jasim Khan, Yuanyuan Guo, Jari Q. Chen, Madison B. Lee, Zhiping Weng, Allen Oak, Prasanth Patcha, Tiffany Mayo, Rajesh Sinha, Venkatram Atigadda, Shahid M. Mukhtar, Jessy S. Deshane, Chander Raman, Carly Elston, Boni E. Elewski, Craig A. Elmets, Mohammad Athar
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106896- (2023)
Summary: Hidradenitis suppurativa (HS) is a skin disorder that causes chronic painful inflammation and hyperproliferation, often with the comorbidity of invasive keratoacanthoma (KA). Our research, employing high-resolution immunofluorescence and dat
Externí odkaz:
https://doaj.org/article/0de4db9502ab4617909eb859b7c9b5e5
Autor:
Andrzej T. Slominski, Tae-Kang Kim, Radomir M. Slominski, Yuwei Song, Shariq Qayyum, Wojciech Placha, Zorica Janjetovic, Konrad Kleszczyński, Venkatram Atigadda, Yuhua Song, Chander Raman, Cornelis J. Elferink, Judith Varady Hobrath, Anton M. Jetten, Russel J. Reiter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15496 (2023)
Melatonin is widely present in Nature. It has pleiotropic activities, in part mediated by interactions with high-affinity G-protein-coupled melatonin type 1 and 2 (MT1 and MT2) receptors or under extreme conditions, e.g., ischemia/reperfusion. In pha
Externí odkaz:
https://doaj.org/article/aedfc88a4e004f4881a92b6461ce04d9
Autor:
Iuliia Dorofeeva, Assylbek Zhylkibayev, Irina V. Saltykova, Venkatram Atigadda, Bibek Adhikari, Oleg S. Gorbatyuk, Maria B. Grant, Marina S. Gorbatyuk
Publikováno v:
Cells, Vol 12, Iss 19, p 2361 (2023)
Previously, the RXR agonist UAB126 demonstrated therapeutic potential to treat obese mice by controlling blood glucose levels (BGL) and altering the expression of genes associated with lipid metabolism and inflammatory response. The purpose of the st
Externí odkaz:
https://doaj.org/article/683c4b8d60be40599fa098b4a29687b7
Autor:
Andrzej T. Slominski, Tae-Kang Kim, Shariq Qayyum, Yuwei Song, Zorica Janjetovic, Allen S. W. Oak, Radomir M. Slominski, Chander Raman, Joanna Stefan, Carlos A. Mier-Aguilar, Venkatram Atigadda, David K. Crossman, Andriy Golub, Yaroslav Bilokin, Edith K. Y. Tang, Jake Y. Chen, Robert C. Tuckey, Anton M. Jetten, Yuhua Song
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract The interactions of derivatives of lumisterol (L3) and vitamin D3 (D3) with liver X receptors (LXRs) were investigated. Molecular docking using crystal structures of the ligand binding domains (LBDs) of LXRα and β revealed high docking sco
Externí odkaz:
https://doaj.org/article/25793fb5b8704b48b8b033ea0ef380e3
Autor:
Raoud Marayati, Laura V. Bownes, Laura L. Stafman, Adele P. Williams, Colin H. Quinn, Venkatram Atigadda, Jamie M. Aye, Jerry E. Stewart, Karina J. Yoon, Elizabeth A. Beierle
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100893- (2021)
Retinoic acid (RA) therapy has been utilized as maintenance therapy for high-risk neuroblastoma, but over half of patients treated with RA relapse. Neuroblastoma stem cell-like cancer cells (SCLCCs) are a subpopulation of cells characterized by the e
Externí odkaz:
https://doaj.org/article/e246226acc30403d9cd1e402f31f9618
Autor:
Mahendra Pratap, Kashyap, Jasim, Khan, Rajesh, Sinha, Lin, Jin, Venkatram, Atigadda, Jessy S, Deshane, Ayesha R, Ahmed, Ali, Kilic, Chander, Raman, M Shahid, Mukhtar, Craig A, Elmets, Mohammad, Athar
Publikováno v:
Seminars in Cell & Developmental Biology. 128:120-129
Hidradenitis suppurativa (HS) is characterized by deep-seated, highly inflamed, and painful lumps/abscesses, fistulae, and sinus tracts that grow extensively deep in the dermis and are highly immunogenic in nature. In about one-third of the HS patien
Autor:
Tae-Kang Kim, Venkatram Atigadda, Pawel Brzeminski, Adrian Fabisiak, Edith K. Y. Tang, Robert C. Tuckey, Andrzej T. Slominski
Publikováno v:
Molecules, Vol 25, Iss 11, p 2583 (2020)
20(S)-Hydroxyvitamin D3 (20(OH)D3) is an endogenous metabolite produced by the action of CYP11A1 on the side chain of vitamin D3 (D3). 20(OH)D3 can be further hydroxylated by CYP11A1, CYP27A1, CYP24A1 and/or CYP27B1 to several hydroxyderivatives. CYP
Externí odkaz:
https://doaj.org/article/7b8cb16eafeb4353bb7f2cf2744c8af2
Autor:
Andrzej T. Slominski, Tae‐Kang Kim, Radomir M. Slominski, Yuwei Song, Zorica Janjetovic, Ewa Podgorska, Sivani B. Reddy, Yuhua Song, Chander Raman, Edith K. Y. Tang, Adrian Fabisiak, Pawel Brzeminski, Rafal R. Sicinski, Venkatram Atigadda, Anton M. Jetten, Michael F. Holick, Robert C. Tuckey
Publikováno v:
The FASEB Journal. 36
Autor:
Nathalia Melo, Olga V. Belyaeva, Wilhelm K. Berger, Laszlo Halasz, Jianshi Yu, Nagesh Pilli, Zhengrong Yang, Alla V. Klyuyeva, Craig A. Elmets, Venkatram Atigadda, Donald D. Muccio, Maureen A. Kane, Laszlo Nagy, Natalia Y. Kedishvili, Matthew B. Renfrow
Publikováno v:
The Journal of biological chemistry.
Retinoid X receptors (RXR) are nuclear transcription factors that partner with other nuclear receptors to regulate numerous physiological processes. Although RXR represents a valid therapeutic target, only a few RXR-specific ligands (rexinoids) have