Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Venkateswarlu Bhamidi"'
Autor:
Allison K. Pymer, Alain De Bruyn, Shane Kipley Kirk, Venkateswarlu Bhamidi, Debangshu Guha, Kim Dumoleijn
Publikováno v:
Organic Process Research & Development. 23:342-354
Industrial R&D organizations often operate under a paradigm in which the scope of process research is narrowed significantly to the extent needed to solve the problem that is hindering the business from moving forward. In this work we discuss an R&D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa10a8a833a83d9c6c9c3f0bf3f59924
https://doi.org/10.1021/acs.oprd.8b00384
https://doi.org/10.1021/acs.oprd.8b00384
Publikováno v:
Crystal Growth & Design. 17:5823-5837
In polythermal experiments, typically the observed dependence of the metastable zone width (MZW – often characterized as the undercooling ΔT) on the experimental path is attributed to the variation of the nucleation rate of solute crystals along t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97a5ed78d9e8ecfb73abf0ba0837af38
https://doi.org/10.1021/acs.cgd.7b00875
https://doi.org/10.1021/acs.cgd.7b00875
Autor:
Su Yu, Calvin L. Becker, Shuang Chen, Venkateswarlu Bhamidi, Ann M. Czyzewski, Ian Marsden, James J. Napier, Chen Ding
Publikováno v:
Organic Process Research & Development. 21:1493-1500
The control of impurity content in active pharmaceutical ingredients is of utmost importance for the pharmaceutical industry. While crystallization is oftentimes used as an efficient and cost-effective means of achieving this purification, structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7392c68ea3976fc3a1a4bf0a816b7815
https://doi.org/10.1021/acs.oprd.7b00145
https://doi.org/10.1021/acs.oprd.7b00145
Publikováno v:
Crystal Growth & Design. 17:1132-1145
The metastable zone in solution crystallization is typically defined as a region of the phase diagram in which no appreciable nucleation occurs. Existing theoretical explanations attribute the appearance of this zone to the low probability of nucleat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c99bc6581348fd3f3bb02067984e757
https://doi.org/10.1021/acs.cgd.6b01529
https://doi.org/10.1021/acs.cgd.6b01529
Autor:
Charles F. Zukoski, Reginald B. H. Tan, Pui Shan Chow, Venkateswarlu Bhamidi, Sie Huey Lee, Paul J. A. Kenis, Guangwen He
Publikováno v:
Crystal Growth & Design. 15:3299-3306
Extensive screening of the polymorph and solvate space of a given active pharmaceutical ingredient molecule is an important step in early-stage pharmaceutical product development. Thus, a significant need exists in the pharmaceutical industry for exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::205a609630bb035f9f774abedee17b64
https://doi.org/10.1021/acs.cgd.5b00420
https://doi.org/10.1021/acs.cgd.5b00420
Autor:
Venkateswarlu Bhamidi, B. P. Abolins
Publikováno v:
Processes
Volume 7
Issue 9
Processes, Vol 7, Iss 9, p 577 (2019)
Volume 7
Issue 9
Processes, Vol 7, Iss 9, p 577 (2019)
Many pharmaceutical molecules, fine chemicals, and proteins exhibit liquid&ndash
liquid phase separation (LLPS, also known as oiling out) during solution crystallization. LLPS is of significant concern in crystallization process development, as
liquid phase separation (LLPS, also known as oiling out) during solution crystallization. LLPS is of significant concern in crystallization process development, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151455514803869489a121a3c8a38726
https://doi.org/10.3390/pr7090577
https://doi.org/10.3390/pr7090577
Autor:
Nicholas C. S. Kee, Paul J. A. Kenis, Charles F. Zukoski, Limay Goh, Venkateswarlu Bhamidi, Kejia Chen, Guangwen He, Richard D. Braatz
Publikováno v:
Crystal Growth & Design. 10:2515-2521
The measured induction times in droplet-based microfluidic systems are stochastic and are not described by the deterministic population balances or moment equations commonly used to model the crystallization of amino acids, proteins, and active pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36bbd4967ee17af5a9417b386179db1
https://doi.org/10.1021/cg900830y
https://doi.org/10.1021/cg900830y
Publikováno v:
Langmuir. 25:4579-4587
Crystallizing solutions of proteins often contain various nonelectrolyte additives that arise from the purification process of proteins or from the reagents employed in the screening kits. Currently, limited knowledge exists about the influence of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77a916dc9d1903a3c336323979d8cc8
https://doi.org/10.1021/la803185m
https://doi.org/10.1021/la803185m
Autor:
Paul J. A. Kenis, Charles F. Zukoski, Reginald B. H. Tan, Scott R. Wilson, Venkateswarlu Bhamidi, Guangwen He
Publikováno v:
Crystal Growth & Design. 6:1746-1749
This study reports the selective growth of γ-glycine crystals via concentrating microdroplets of aqueous glycine solutions through slow evaporation of water using an evaporation-based crystallization platform. In prior studies, γ-glycine crystals c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a76559f2b9c3992a6eb38f9cc4edb8e
https://doi.org/10.1021/cg0602515
https://doi.org/10.1021/cg0602515
Publikováno v:
Crystal Growth & Design. 6:1175-1180
In this work, we identified a single critical supersaturation, the level of supersaturation above which nucleation will occur instantaneously, for each of a range of compounds: the amino acids glycine and l-histidine, the pharmaceutical paracetamol,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b0c3c2cdcea55f2fa64e8c9958ffdd
https://doi.org/10.1021/cg050681f
https://doi.org/10.1021/cg050681f