Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Venkateswara R Gogulamudi"'
Autor:
Venkateswara R Gogulamudi, Md Torikul Islam, Jessica R Durrant, Adelola O Adeyemo, Daniel W Trott, Mi Ho Hyuhn, Weiquan Zhu, Anthony J Donato, Ashley E Walker, Lisa A Lesniewski
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285253 (2023)
Atherosclerosis is the root cause of major cardiovascular diseases (CVD) such as myocardial infarction and stroke. ADP-ribosylation factor 6 (Arf6) is a ubiquitously expressed GTPase known to be involved in inflammation, vascular permeability and is
Externí odkaz:
https://doaj.org/article/761f35e1bc9a45a1a094e94b04c8024a
Autor:
Venkateswara R. Gogulamudi, Danielle Y. Arita, Camille R. T. Bourgeois, Justine Jorgensen, Jing He, William C. Wimley, Ryosuke Satou, Alexis A. Gonzalez, Minolfa C. Prieto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Growing evidence indicates that prorenin receptor (PRR) is upregulated in collecting duct (CD) of diabetic kidney. Prorenin is secreted by the principal CD cells, and is the natural ligand of the PRR. PRR activation stimulates fibrotic facto
Externí odkaz:
https://doaj.org/article/a8a795260c5844b2a75c6453cf8deb72
Autor:
Venkateswara R. Gogulamudi, Daniel R. Machin, Grant D. Henson, Jisok Lim, Richard C. Bramwell, Jessica R. Durrant, Anthony J. Donato, Lisa A. Lesniewski
Publikováno v:
Physiological Reports, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Increased arterial stiffness is a cardiovascular disease risk factor in the setting of advancing age and Western diet (WD) induced obesity. Increases in large artery stiffness, as measured by pulse wave velocity (PWV), occur within 8 weeks o
Externí odkaz:
https://doaj.org/article/0b75c14bb4da4a0ea88979eee6987ac6
Autor:
Andrew C. Curnow, Sabrina R. Gonsalez, Venkateswara R. Gogulamudi, Bruna Visniauskas, Eric E. Simon, Alexis A. Gonzalez, Dewan S. A. Majid, Lucienne S. Lara, Minolfa C. Prieto
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
In the kidney, the stimulation of renin production by the collecting duct (CD-renin) contributes to the development of hypertension. The CD is a major nephron segment for the synthesis of nitric oxide (NO), and low NO bioavailability in the renal med
Externí odkaz:
https://doaj.org/article/7c8cf8ea09844711ab9a0667fca1f812
Autor:
Sabrina R. Gonsalez, Dayene S. Gomes, Alessandro M. de Souza, Fernanda M. Ferrão, Zoe Vallotton, Venkateswara R. Gogulamudi, Jennifer Lowe, Dulce E. Casarini, Minolfa C. Prieto, Lucienne S. Lara
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7887
The Na+-activated Na+ channel (Nax) and salt-inducible kinase (SIK) are stimulated by increases in local Na+ concentration, affecting (Na+ + K+)-ATPase activity. To test the hypothesis that the triad Nax/SIK/(Na+ + K+)-ATPase contributes to kidney in
Autor:
Venkateswara R. Gogulamudi, Jessica R. Durrant, Adelola O. Adeyemo, Huynh Mi Ho, Ashley E. Walker, Lisa A. Lesniewski
Publikováno v:
GeroScience.
Using multiple mouse models, we explored the impact of aging on the size and severity of atherosclerotic lesions. In young, middle-aged and old apolipoprotein E knockout mice (ApoE−/−) fed an atherogenic diet (AD) for 3–8 weeks, plaque/atheroma
Autor:
Daniel R. Machin, Daniel W. Trott, Venkateswara R. Gogulamudi, Md. Torikul Islam, Samuel I. Bloom, Hans Vink, Lisa A. Lesniewski, Anthony J. Donato
Publikováno v:
Geroscience. Springer International Publishing
Advanced age is accompanied by arterial dysfunction, as well as a diminished glycocalyx, which may be linked to reduced high molecular weight-hyaluronan (HMW-HA) synthesis. However, the impact of glycocalyx deterioration in age-related arterial dysfu
Autor:
William C. Wimley, Camille R. T. Bourgeois, Jing He, Venkateswara R Gogulamudi, Minolfa C. Prieto, Danielle Y Arita, Ryosuke Satou, Justine Jorgensen, Alexis A. Gonzalez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Growing evidence indicates that prorenin receptor (PRR) is upregulated in collecting duct (CD) of diabetic kidney. Prorenin is secreted by the principal CD cells, and is the natural ligand of the PRR. PRR activation stimulates fibrotic factors, inclu
Autor:
Daniel W. Trott, Anthony J. Donato, Lisa A. Lesniewski, Venkateswara R Gogulamudi, David J Buckley, Eric S. Sorensen, Tam T. T. Phuong, Tavia Dutson, Jinjin Cai, Torikul Islam
Publikováno v:
GeroScience. 43:1331-1347
Both glucose tolerance and adaptive immune function exhibit significant age-related alterations. The influence of the immune system on obesity-associated glucose intolerance is well characterized; however, whether the immune system contributes to age
Autor:
Chandramohan Ramasamy, Kailash N. Pandey, Prerna Kumar, Ramachandran Samivel, Daniel R. Kapusta, Hanqing Zhao, Kandasamy Neelamegam, Christian Nguyen, Venkateswara R Gogulamudi, Huijing Xia
Publikováno v:
The FASEB Journal. 35