Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Venkateshwar Rao Gummadi"'
Autor:
Kumari Mahasweta, Manoj Rajappa, Sangeetha Raghuramachandran, Mohammadjavad Paydar, Anirudha Lakshminarasimhan, Sujatha Rajagopalan, Anuradha Ramanathan, Murali Ramachandra, Subramanya Hosahalli, Venkateshwar Rao Gummadi, Sunil Kumar Panigrahi, Bharathi Raja Ainan, Narasimha Rao Krishnamurthy, Srinivas Nanduri, Mohammad Rais Mustafa, Pooi-Fong Wong, Chung Yeng Looi, Girish Aggunda Renukappa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4911-4918
We have identified a novel 7-azaindole series of anaplastic lymphoma kinase (ALK) inhibitors. Compounds 7b, 7 m and 7 n demonstrate excellent potencies in biochemical and cellular assays. X-ray crystal structure of one of the compounds (7 k) revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1661e6f48afd066e936eb2b3e55a3381
https://doi.org/10.1016/j.bmcl.2013.06.071
https://doi.org/10.1016/j.bmcl.2013.06.071
Autor:
Thomas Antony, Shekar Chelur, Chetan Pandit, Kavitha Nellore, Sreevalsam Gopinath, Girish Daginakatte, Bharathi Raja Ainan, Aravind Basavaraju, Subhendu Mukherjee, Venkateshwar Rao Gummadi, Murali Ramachandra, Susanta Samajdar, Sanjeev Giri, Sivapriya Marappan, Wesley Roy Balasubramanian
Publikováno v:
Cancer Research. 76:4798-4798
Interleukin-1 receptor associated kinases (IRAKs) are serine/threonine protein kinases belonging to the tyrosine-like kinase (TLK) family. IRAKs function as mediators of Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf485254e7603791b9fd90480378f12
https://doi.org/10.1158/1538-7445.am2016-4798
https://doi.org/10.1158/1538-7445.am2016-4798