Zobrazeno 1 - 10
of 1 524
pro vyhledávání: '"Venkatesh L"'
Autor:
Minoo Bagheri, Andrei Bombin, Mingjian Shi, Venkatesh L. Murthy, Ravi Shah, Jonathan D. Mosley, Jane F. Ferguson
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Circulating metabolites act as biomarkers of dysregulated metabolism and may inform disease pathophysiology. A portion of the inter-individual variability in circulating metabolites is influenced by common genetic variation. We evaluate
Externí odkaz:
https://doaj.org/article/2f77faa24aa44d18b86b6e3ac4fdac85
Autor:
Matthew Nayor, Priya Gajjar, Patricia Miller, Venkatesh L. Murthy, Ravi V. Shah, Nicholas E. Houstis, Raghava S. Velagaleti, Martin G. Larson, Ramachandran S. Vasan, Gregory D. Lewis, Gary F. Mitchell
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background During exercise, a healthy arterial system facilitates increased blood flow and distributes it effectively to essential organs. Accordingly, we sought to understand how arterial stiffening might impair cardiorespiratory fitness in communit
Externí odkaz:
https://doaj.org/article/39cae384aa64483187b7d78039fb5ffc
Autor:
Ravi V. Shah, Shih‐Jen Hwang, Venkatesh L. Murthy, Shilin Zhao, Kahraman Tanriverdi, Priya Gajjar, Kevin Duarte, Mark Schoenike, Robyn Farrell, Liana C. Brooks, Deepa M. Gopal, Jennifer E. Ho, Nicholas Girerd, Ramachandran S. Vasan, Daniel Levy, Jane E. Freedman, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background While exercise impairments are central to symptoms and diagnosis of heart failure with preserved ejection fraction (HFpEF), prior studies of HFpEF biomarkers have mostly focused on resting phenotypes. We combined precise exercise phenotype
Externí odkaz:
https://doaj.org/article/2306c9218f714b4c81c636939db51d48
Autor:
Rachel G. Kroll, Corey Powell, Jun Chen, Natasha T. Snider, Cynthia St. Hilaire, Akshay Reddy, Judy Kim, David J. Pinsky, Venkatesh L. Murthy, Nadia R. Sutton
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 9 (2023)
Background Ectonucleotidases maintain vascular homeostasis by metabolizing extracellular nucleotides, modulating inflammation and thrombosis, and potentially, myocardial flow through adenosine generation. Evidence implicates dysfunction or deficiency
Externí odkaz:
https://doaj.org/article/9cb0e3342def42b2ac15ae5b602fd5ba
Autor:
Olsi Gjyshi, Adam Grippin, Lauren Andring, Anuja Jhingran, Lilie L. Lin, Julianna Bronk, Patricia J. Eifel, Melissa M. Joyner, Jagannadha K. Sastry, Kyoko Yoshida-Court, Travis N. Solley, Tatiana Cisneros Napravnik, Madison P. O'Hara, Venkatesh L Hegde, Lauren E. Colbert, Ann H Klopp
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 39, Iss , Pp 100578- (2023)
Purpose: The immune system’s role in mediating the cytotoxic effects of chemoradiotherapy remains not completely understood. The integration of immunotherapies into treatment will require insight into features and timing of the immune microenvironm
Externí odkaz:
https://doaj.org/article/7f3ed66fbc544424af486805649d57a8
Autor:
George Hindy, Daniel J. Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla, Hui Wang, Pennelope Blakely, Ayse Bilge Ozel, Sarah Graham, Grace H. Holton, Joseph Dowsett, Akl C. Fahed, Kingsley-Michael Amadi, Grace K. Erne, Annika Tekmulla, Anis Ismail, Christopher Launius, Nona Sotoodehnia, James S. Pankow, Lise Wegner Thørner, Christian Erikstrup, Ole Birger Pedersen, Karina Banasik, Søren Brunak, Henrik Ullum, Jesper Eugen-Olsen, Sisse Rye Ostrowski, on behalf of the DBDS Consortium, Mary E. Haas, Jonas B. Nielsen, Luca A. Lotta, on behalf of the Regeneron Genetics Center, Gunnar Engström, Olle Melander, Marju Orho-Melander, Lili Zhao, Venkatesh L. Murthy, David J. Pinsky, Cristen J. Willer, Susan R. Heckbert, Jochen Reiser, Daniel R. Goldstein, Karl C. Desch, Salim S. Hayek
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which are strongly associated with
Externí odkaz:
https://doaj.org/article/97725ccf03d44b8f8179f849f6db2e96
Autor:
John T. Wilkins, Hongyan Ning, Allan Sniderman, Neil Stone, James Otvos, David R. Jacobs, Jr., Ravi Shah, Venkatesh L. Murthy, Jamal Rana, Norrina Allen, Donald M. Lloyd-Jones
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 12, Pp 100299- (2022)
The cumulative exposure to apolipoprotein B (apoB)-containing lipoproteins in the blood during early adult life is a central determinant of atherosclerotic cardiovascular disease risk. To date, the patterns and rates of change in apoB through early a
Externí odkaz:
https://doaj.org/article/8c10e7e1cae447dda2a3d11d5afcdecb
Autor:
Ravi V. Shah, Patricia Miller, Laura A. Colangelo, Ariel Chernofsky, Nicholas E. Houstis, Rajeev Malhotra, Raghava S. Velagaleti, David R. Jacobs, Kelley Pettee Gabriel, Jared P. Reis, Donald M. Lloyd‐Jones, Clary B. Clish, Martin G. Larson, Ramachandran S. Vasan, Venkatesh L. Murthy, Gregory D. Lewis, Matthew Nayor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 18 (2022)
Background Cardiorespiratory fitness is a powerful predictor of health outcomes that is currently underused in primary prevention, especially in young adults. We sought to develop a blood‐based biomarker of cardiorespiratory fitness that is easily
Externí odkaz:
https://doaj.org/article/ce9210ddf49f4eae8a87ada3be137a9e
Autor:
Travis T. Sims, Molly B. El Alam, Tatiana V. Karpinets, Stephanie Dorta-Estremera, Venkatesh L. Hegde, Sita Nookala, Kyoko Yoshida-Court, Xiaogang Wu, Greyson W. G. Biegert, Andrea Y. Delgado Medrano, Travis Solley, Mustapha Ahmed-Kaddar, Bhavana V. Chapman, K. Jagannadha Sastry, Melissa P. Mezzari, Joseph F. Petrosino, Lilie L. Lin, Lois Ramondetta, Anuja Jhingran, Kathleen M. Schmeler, Nadim J. Ajami, Jennifer Wargo, Lauren E. Colbert, Ann H. Klopp
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Travis Sims and Molly El Alam et al. show that diversity of gut microbiota is associated with a favorable response to chemoradiation for cervical cancer and use flow cytometry to show that patients with high microbiome diversity had increased tumor i
Externí odkaz:
https://doaj.org/article/c76ee253ea0f4e5b85dab20f72cbe758
Autor:
Jessica R. Golbus, Sarah Adie, Matheos Yosef, Venkatesh L. Murthy, Keith D. Aaronson, Matthew C. Konerman
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 2074-2081 (2020)
Abstract Aims Statins improve survival and reduce rejection and cardiac allograft vasculopathy after heart transplantation (HT). The impact of different statin intensities on clinical outcomes has never been assessed. We set out to determine the impa
Externí odkaz:
https://doaj.org/article/c824bbd0120c41e5bd919cbcf0615acb