Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Venkatesh Hariharan"'
Autor:
Doug A Medvetz, Damir Khabibullin, Venkatesh Hariharan, Pat P Ongusaha, Elena A Goncharova, Tanja Schlechter, Thomas N Darling, Ilse Hofmann, Vera P Krymskaya, James K Liao, Hayden Huang, Elizabeth P Henske
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47842 (2012)
Birt-Hogg-Dube (BHD) is a tumor suppressor gene syndrome associated with fibrofolliculomas, cystic lung disease, and chromophobe renal cell carcinoma. In seeking to elucidate the pathogenesis of BHD, we discovered a physical interaction between folli
Externí odkaz:
https://doaj.org/article/ee25e5953e1d4c7f83be50684daa1507
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e27064 (2011)
Control over cell viability is a fundamental property underlying numerous physiological processes. Cell spreading on a substrate was previously demonstrated to be a major factor in determining the viability of individual cells. In multicellular organ
Externí odkaz:
https://doaj.org/article/5315c011f8b54e7b90040024987e3968
Publikováno v:
Food and Chemical Toxicology. 71:68-73
The toxic effects of acrylamide on cytoskeletal integrity and ion channel balance is well-established in many cell types, but there has been little examination regarding the effects of acrylamide on primary cardiomyocytes, despite the importance of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b3b2906c07caa64710943a43757b45
https://doi.org/10.1016/j.fct.2014.05.029
https://doi.org/10.1016/j.fct.2014.05.029
Autor:
Beibei Cai, Victor Zamora, Venkatesh Hariharan, Cuong Nguyen, Godfrey L. Smith, Jennifer B. Pierson, Renjun Zhu, Emily R. Pfeiffer-Kaushik, Gary Gintant, Graham Dempsey, Maria P. Hortigon-Vinagre, Randall S. Ingermanson, Shuyun Feng, Leslie Tung
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106612
Introduction:\ud \ud Voltage-sensitive optical (VSO) sensors offer a minimally invasive method to study the time course of repolarization of the cardiac action potential (AP). This Comprehensive in vitro Proarrhythmia Assay (CiPA) cross-platform stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21465a7d7bc9e554f2e930e3fe4696f7
https://doi.org/10.1016/j.vascn.2019.106612
https://doi.org/10.1016/j.vascn.2019.106612
Publikováno v:
Cellular and Molecular Bioengineering. 2:177-189
The 14–18 amino acid kinesin neck linker domain links the core motor to the coiled-coil dimerization domain. One puzzle is that the neck linker appears too short for the 4 nm distance each linker must stretch to enable an 8 nm step – when modeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f839ba9c743f24f0928331deb74dd88a
https://doi.org/10.1007/s12195-009-0059-5
https://doi.org/10.1007/s12195-009-0059-5
Autor:
Venkatesh Hariharan, Jeffrey E. Saffitz, Angeliki Asimaki, Jarett Michaelson, Eva Plovie, Calum A. MacRae, Hayden Huang
Aims The majority of patients diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) have mutations in genes encoding desmosomal proteins, raising the possibility that abnormal intercellular adhesion plays an important role in disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366a814d869b9e1deb48f4b95e291626
https://europepmc.org/articles/PMC4296114/
https://europepmc.org/articles/PMC4296114/
Autor:
Hayden Huang, Jane J. Yu, Venkatesh Hariharan, Rebecca M. Baron, Andrey A. Parkhitko, Chenggang Li, Miguel A. Pinilla, Erik Zhang, Douglas A. Medvetz, Maria Laucho Contreras, Elizabeth P. Henske, Anja Hergrueter, Damir Khabibullin, Caroline A. Owen
Publikováno v:
Physiological Reports
Germline loss‐of‐function BHD mutations cause cystic lung disease and hereditary pneumothorax, yet little is known about the impact of BHD mutations in the lung. Folliculin (FLCN), the product of the Birt–Hogg–Dube (BHD) gene, has been linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531d4f6cf6b9c09653f67f463a000005
https://pubmed.ncbi.nlm.nih.gov/25121506
https://pubmed.ncbi.nlm.nih.gov/25121506
Currently, many diabetic cardiomyopathy (DC) studies focus on either in vitro molecular pathways or in vivo whole-heart properties such as ejection fraction. However, as DC is primarily a disease caused by changes in structural and functional propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59db80ae132cb4a9179bee0248ab7ce1
https://europepmc.org/articles/PMC4052244/
https://europepmc.org/articles/PMC4052244/
Publikováno v:
Cardiovascular engineering and technology. 3(1)
The right ventricular apex (RVA) is a potential hot spot for development of cardiac rhythm anomalies. Many conditions, including arrhythmogenic right ventricular cardiomyopathy and Brugada's syndrome affect the RVA, and further, the RVA remains an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a11ee4d992bfc3c8f2233b2f70c3a9
https://pubmed.ncbi.nlm.nih.gov/24416088
https://pubmed.ncbi.nlm.nih.gov/24416088
Publikováno v:
Biophysical Journal. 104:492a
Introduction: Mechanotransduction is the process by which cells couple their external and internal environments by transducing mechanical stimuli into a biochemical response. While this process is responsible for regulating cell fate through gene exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10982bfe68eb1bc7c08697da8f229bc
https://doi.org/10.1016/j.bpj.2012.11.2711
https://doi.org/10.1016/j.bpj.2012.11.2711