Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Venkatesh, Rajapurohitam"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:512-521
We determined whether North American ginseng (Panax quinquefolius L.) mitigates the effect of angiotensin II on hypertrophy and heart failure. Angiotensin II (0.3 mg/kg) was administered to rats for 2 or 4 weeks in the presence or absence of ginseng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b961ff14c0fef06acad90a748b3ae9c2
https://doi.org/10.1139/cjpp-2020-0480
https://doi.org/10.1139/cjpp-2020-0480
Autor:
Suresh C Bairwa, Venkatesh Rajapurohitam, Xiaohong Tracey Gan, Rabban Mangat, Spencer D Proctor, Morris Karmazyn
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145992 (2016)
White adipocytes are known to function as endocrine organs by secreting a plethora of bioactive adipokines which can regulate cardiac function including the development of hypertrophy. We determined whether adipose tissue conditioned medium (ATCM) ge
Externí odkaz:
https://doaj.org/article/6019e663430a473cad420c56c8452c97
Inhibition of angiotensin II-induced hypertrophy and cardiac dysfunction by North American ginseng (
Autor:
Xilan, Tang, Xiaohong Tracey, Gan, Chian Ju, Jong, Venkatesh, Rajapurohitam, Morris, Karmazyn
Publikováno v:
Canadian journal of physiology and pharmacology. 99(5)
We determined whether North American ginseng (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a582702b9e374a078e50f3fa78e7809b
https://pubmed.ncbi.nlm.nih.gov/33091308
https://pubmed.ncbi.nlm.nih.gov/33091308
Autor:
Eduardo Martinez-Abundis, Venkatesh Rajapurohitam, James V Haist, Xiaohong T Gan, Morris Karmazyn
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41612 (2012)
The obesity-related 16 kDa peptide leptin is synthesized primarily in white adipocytes although its production has been reported in other tissues including the heart. There is emerging evidence that leptin may contribute to cardiac pathology especial
Externí odkaz:
https://doaj.org/article/f5077d51192b41e4963d0bb8dc3f1bec
Autor:
Xilan Tang, Jenny Xue, Xiaohong Tracey Gan, Cathy Huang, Morris Karmazyn, Venkatesh Rajapurohitam, Edmund M.K. Lui
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 94:1325-1335
There is increasing evidence for a beneficial effect of ginseng on cardiac pathology. Here, we determined whether North American ginseng can modulate the deleterious effects of the β-adrenoceptor agonist isoproterenol on cardiac hypertrophy and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2bdb7d852535e65120e91f296b6b03
https://doi.org/10.1139/cjpp-2016-0337
https://doi.org/10.1139/cjpp-2016-0337
Publikováno v:
Molecular and Cellular Biochemistry. 408:155-162
Leptin is a 16 kDa pro-satiety peptide produced primarily not only by white adipocytes but also by numerous other tissues including the heart. Circulating leptin exerts its effect through specific receptors, although its principle actions are depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2a88662d6c6efcd7574115ca29ca68
https://doi.org/10.1007/s11010-015-2491-2
https://doi.org/10.1007/s11010-015-2491-2
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 351:492-499
Na(+)/H(+) exchanger 1 (NHE-1) inhibition attenuates the hypertrophic response and heart failure in various experimental models. As the hypertrophic program is rapidly initiated following insult, we investigated whether early and transient administra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffae9f82f1add9406f68e61a0ecf29bd
https://doi.org/10.1124/jpet.114.217091
https://doi.org/10.1124/jpet.114.217091
Autor:
Morris Karmazyn, Venkatesh Rajapurohitam, Gregory B. Gloor, James V. Haist, Glynn Martin, Grace Ettinger, Cathy Huang, Xiaohong Tracey Gan, Gregor Reid, Jonathan R. Swann, James E. Sidaway, Jeremy P. Burton
Publikováno v:
Circulation: Heart Failure. 7:491-499
Background— Probiotics are extensively used to promote gastrointestinal health, and emerging evidence suggests that their beneficial properties can extend beyond the local environment of the gut. Here, we determined whether oral probiotic administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f08ee1d6ed617d89c3d6e849d49862a
https://doi.org/10.1161/circheartfailure.113.000978
https://doi.org/10.1161/circheartfailure.113.000978
Publikováno v:
Current Pharmaceutical Design. 20:646-651
The identification of the adipocyte as a source of production of biologically-active peptides has materialized into an active area of research related to the role of these peptides in physiology and pathophysiology. Moreover, this research has result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5762c1a3ee8785a6adf1b7effdf8ed4
https://doi.org/10.2174/13816128113199990023
https://doi.org/10.2174/13816128113199990023
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 91:883-888
Leptin is a 16 kDa peptide that was first identified in 1994 through positional cloning of the mouse obesity gene. Although the primary function of leptin is to act a satiety factor through its actions on the hypothalamus, it is now widely recognized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4a47d41f5f9a188bf9be8b07932a58
https://doi.org/10.1139/cjpp-2013-0057
https://doi.org/10.1139/cjpp-2013-0057