Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Venkatasubbaiah A. Venkatesha"'
Autor:
Venkatasubbaiah A. Venkatesha, Leslie A. Parsels, Joshua D. Parsels, Lili Zhao, Sonya D. Zabludoff, Diane M. Simeone, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 6, Pp 519-525 (2012)
Checkpoint kinase 1 (Chk1) inhibition sensitizes pancreatic cancer cells and tumors to gemcitabine. We hypothesized that Chk1 inhibition would sensitize pancreatic cancer stem cells to gemcitabine. We tested this hypothesis by using two patient-deriv
Externí odkaz:
https://doaj.org/article/750c64e2ce42448492a895966153fb3a
Publikováno v:
International Journal of Complementary & Alternative Medicine. 3
The antineoplastic activity of chloroform stem bark extract of rohituka Aphanamixis polystachya APE used traditionally to treat spleen and liver tumors was evaluated in cultured HeLa cells by clonogenic and micronucleus assays Treatment of HeLa cells
Autor:
Joshua D. Parsels, Meredith A. Morgan, Diane M. Simeone, Sonya Zabludoff, Leslie A. Parsels, Venkatasubbaiah A. Venkatesha, Theodore S. Lawrence, Jonathan Maybaum, Lili Zhao
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 6, Pp 519-525 (2012)
Checkpoint kinase 1 (Chk1) inhibition sensitizes pancreatic cancer cells and tumors to gemcitabine. We hypothesized that Chk1 inhibition would sensitize pancreatic cancer stem cells to gemcitabine. We tested this hypothesis by using two patient-deriv
Autor:
Changbin Du, Zhen Gao, Leena Chaudhuri, Amanda L. Kalen, Venkatasubbaiah A. Venkatesha, Joseph J. Cullen, Prabhat C. Goswami, Douglas R. Spitz, Larry W. Oberley
Publikováno v:
Cancer Biology & Therapy. 8:1962-1971
Manganese superoxide dismutase (SOD2) is a nuclear encoded and mitochondria localized antioxidant enzyme that converts mitochondria derived superoxide to hydrogen peroxide. This study investigates the hypothesis that mitochondria derived reactive oxy
Publikováno v:
Nutrition Research. 26:303-311
Ionizing radiations induce free radicals that lead to a cascade of events causing damage to cellular DNA. It is generally accepted that cell death induced by ionizing irradiation is due to DNA double-strand breaks. Therefore, agents that can neutrali
Autor:
Vinay Sonawane, Dimple Bhatia, Prashant Tannu, Veena R Agarwal, Vaibhavi J Lad, Prashant Pandey, Somesh Sharma, Magesh Venkataraman, Ankita Srivastava, Venkatasubbaiah A. Venkatesha, Vijaykumar Deore, Ramachandra Sangana, Asavari Joshi, Tausif Ahmed, Anagha Damre, Sarika Choudhari, Julie Bose, Bichismita Sahu, Sanjay Kumar
Publikováno v:
Molecular Cancer
Background Lung cancer is the major cause of cancer-related deaths and many cases of Non Small Cell Lung Cancer (NSCLC), a common type of lung cancer, have frequent genetic/oncogenic activation of EGFR, KRAS, PIK3CA, BRAF, and others that drive tumor
Publikováno v:
Biological & Pharmaceutical Bulletin. 28:69-77
The effect of radiation on tumor tissue can be optimized by adding radiosensitizing agents, in order to achieve a greater degree of tumor damage than expected from the use of either treatment alone. The ethanolic extract of Aphanamixis polystachya (A
Autor:
Tiyyagura Koti Reddy, Rajendra Kedlaya, Ganesh Chandra Jagetia, Venkatasubbaiah A. Venkatesha
Publikováno v:
Clinica Chimica Acta. 347:189-197
Background: Iron is essential for oxygen transport and a variety of cellular processes like respiration and DNA synthesis. It may become toxic when not handled carefully by cellular proteins and shielded from surrounding media. Naringin treatment may
2,2′,4,4′,5,5′-Hexachlorobiphenyl (PCB-153) is a non-metabolizable environmental chemical contaminant commonly found in breast milk of PCB exposed individuals, suggesting that chronic exposure to PCB-153 could have adverse health effects. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a51761eaa8d91c4bdd3c645634831d
https://europepmc.org/articles/PMC2891036/
https://europepmc.org/articles/PMC2891036/
Autor:
Amanda L. Kalen, Ehab H. Sarsour, Garry R. Buettner, Hans-Joachim Lehmler, Venkatasubbaiah A. Venkatesha, Larry W. Robertson, Prabhat C. Goswami, Sujatha Venkataraman
Polychlorinated biphenyls (PCBs) are environmental chemical contaminants believed to adversely affect cellular processes. We investigated the hypothesis that PCB-induced changes in the levels of cellular reactive oxygen species (ROS) induce DNA damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1ced3892f58835d9b9f7ff33ff4c20
https://europepmc.org/articles/PMC2614346/
https://europepmc.org/articles/PMC2614346/