Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Venkatasamy Manivel"'
Autor:
Parul Mehrotra, Shilpa V Jamwal, Najmuddin Saquib, Neeraj Sinha, Zaved Siddiqui, Venkatasamy Manivel, Samrat Chatterjee, Kanury V S Rao
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004265 (2014)
The success of Mycobacterium tuberculosis as a pathogen derives from its facile adaptation to the intracellular milieu of human macrophages. To explore this process, we asked whether adaptation also required interference with the metabolic machinery
Externí odkaz:
https://doaj.org/article/0af258e6759c41edb7411f061e5363b5
Autor:
Shingar, Sharma, R S, Rajmani, Arun, Kumar, Ashima, Bhaskar, Amit, Singh, Venkatasamy, Manivel, Anil K, Tyagi, Kanury V S, Rao
Publikováno v:
Indian journal of experimental biology. 53(7)
Unsatisfactory performance of the existing BCG vaccines, especially against the adult pulmonary disease, has urged the need for an effective vaccine against tuberculosis (TB). In this study, we employed differential proteomics to obtain a list of ant
Publikováno v:
Immunity. 24(4):429-438
SummaryCorrelation between the promiscuity of the primary antibody response and conformational flexibility in a germline antibody was addressed by using germline antibody 36-65. Crystallographic analyses of the 36-65 Fab with three independent dodeca
Publikováno v:
International Journal of Proteomics
Even though endoplasmic reticulum (ER) stress associated with mycobacterial infection has been well studied, the molecular basis of ER as a crucial organelle to determine the fate of Mtb is yet to be established. Here, we have studied the ability of
Autor:
Kanury V. S. Rao, Samrat Chatterjee, Zaved Siddiqui, Shilpa Jamwal, Najmuddin Mohd Saquib, Neeraj Sinha, Parul Mehrotra, Venkatasamy Manivel
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004265 (2014)
PLoS Pathogens
PLoS Pathogens
The success of Mycobacterium tuberculosis as a pathogen derives from its facile adaptation to the intracellular milieu of human macrophages. To explore this process, we asked whether adaptation also required interference with the metabolic machinery
Publikováno v:
The Journal of Immunology. 164:5615-5625
We examine the etiological basis of hierarchical immunodominance of B cell epitopes on a multideterminant Ag. A model T-dependant immunogen, containing a single immunodominant B cell epitope, was used. The primary IgM response to this peptide include
Autor:
Bishnu P. Nayak, Renu Tuteja, Venkatasamy Manivel, Rajendra P. Roy, Ram A. Vishwakarma, Kanury V. S. Rao
Publikováno v:
The Journal of Immunology. 161:3510-3519
The influence of imposing various conformational constraints on immune responses to a model epitope within a synthetic peptide immunogen was examined in mice. Although overall immunogenicity was affected, the model epitope (sequence DPAF) remained th
Autor:
Mukul Kumar Midha, Kanury V. S. Rao, Atanu Basu, Shilpa Jamwal, H. N. Verma, Venkatasamy Manivel
Publikováno v:
Scientific Reports
To probe how the pathogen Mycobacterium tuberculosis controls host cellular death pathways, we compared mitochondrial responses in human macrophages infected either with the avirulent mycobacterial strain H37Ra, or its virulent counterpart H37Rv. Fol
Autor:
Kanury V. S. Rao, Kamiya Tikoo, H. N. Verma, Simarjeet Kaur, Venkatasamy Manivel, Neeraj Sinha, Mukul Kumar Midha, Samrat Chatterjee
Publikováno v:
Journal of proteome research. 11(12)
Molecular mechanism governing biological processes leading to dietary obesity and diabetes are largely unknown. Here we study the liver proteome differentially expressed in a long-term high-fat and high-sucrose diet (HFHSD)-induced obesity and diabet
Autor:
Shyamashree Dasgupta, Bikash Ranjan Giri, P.S. Parameswaran, Bishnupada Roy, Venkatasamy Manivel
Publikováno v:
Veterinary parasitology. 185(2-4)
The stem bark of Acacia oxyphylla Graham ex Bentham is used as an anthelmintic by the natives of Mizoram (North-East India). Therefore, the aim of the study was to assess the effect of the active compound isolated from A. oxyphylla on the tegument of