Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Venkata Mahidhar Yenugonda"'
Publikováno v:
BioTechniques. 68:180-184
CRISPR–Cas9 has proven to be a versatile tool for the discovery of essential genetic elements involved in various disease states. CRISPR-assisted dense mutagenesis focused on therapeutically challenging protein complexes allows us to systematically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de3ab85043dbfef3fd5ad6fcd200922
https://doi.org/10.2144/btn-2019-0100
https://doi.org/10.2144/btn-2019-0100
Autor:
Varsha Harish, Sophie Coste, Stanley T. Fricke, Gary M. Kupfer, Muhammad S. Noon, Olga Rodriguez, Erika Parasido, Chris Albanese, Venkata Mahidhar Yenugonda, Aisha Naeem, Emanuel F. Petricoin, Lawrence F. Kromer, Maria Avantaggiati, Mariaelena Pierobon, Chukuemeka Ihemelandu, Muhammad Umer Choudhry
Publikováno v:
Mol Cancer Res
In medulloblastoma, p53 expression has been associated with chemoresistance and radiation resistance and with poor long-term outcomes in the p53-mutated sonic hedgehog, MYC-p53, and p53-positive medulloblastoma subgroups. We previously established a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1f8552215a5f76e6c5eb40858aa290
https://europepmc.org/articles/PMC8738155/
https://europepmc.org/articles/PMC8738155/
Autor:
Achal S. Achrol, Anubhab Mukherjee, Santosh Kesari, Ariana K Waters, Venkata Mahidhar Yenugonda, Pranav Kalyan
Publikováno v:
International Journal of Nanomedicine. 14:1937-1952
Lipid-polymer hybrid nanoparticles (LPHNPs) are next-generation core-shell nanostructures, conceptually derived from both liposome and polymeric nanoparticles (NPs), where a polymer core remains enveloped by a lipid layer. Although they have garnered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7392d94740a44bbd27b3c32d710d0c0
https://doi.org/10.2147/ijn.s198353
https://doi.org/10.2147/ijn.s198353
Autor:
Tiffany Juarez, Venkata Mahidhar Yenugonda, Santosh Kesari, Mark C. Glassy, Elmar Nurmemmedov, Ivan Babic, Sandeep C. Pingle, Natsuko Nomura
Publikováno v:
Human Antibodies. 26:95-101
Immunotherapy is now at the forefront of cancer therapeutic development. Gliomas are a particularly aggressive form of brain cancer for which immunotherapy may hold promise. Pritumumab (also known in the literature as CLNH11, CLN-IgG, and ACA-11) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d5a29b9dc739a2d4052f44d8eea716
https://doi.org/10.3233/hab-170326
https://doi.org/10.3233/hab-170326
Autor:
Ariana K Waters, Sandeep Burma, Annamarie Allnutt, Natsuko Nomura, Yueqin Quan, Elmar Nurmemmedov, Nozomi Tomimatsu, Ivan Babic, Venkata Mahidhar Yenugonda, Santosh Kesari
Publikováno v:
Neuro Oncol
Glioblastoma (GBM) is considered one of the most lethal forms of human cancers, and despite considerable advances in multimodality treatments, it remains an incurable disease with an overall survival of 14 to 16 months after diagnosis. Even in the er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a91db327be778a2e59b248f76664b38
https://europepmc.org/articles/PMC7650350/
https://europepmc.org/articles/PMC7650350/
Autor:
Nam-Gu Her, Pengfei Jiang, Santosh Kesari, Elmar Nurmemmedov, Venkata Mahidhar Yenugonda, Rajesh Mukthavaram, Natsuko Nomura, Jatin Roper, Ivan Babic, Anton Cheltsov
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abnormal regulation of β-catenin initiates an oncogenic program that serves as a main driver of many cancers. Albeit challenging, β-catenin is an attractive drug target due to its role in maintenance of cancer stem cells and potential to eliminate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef8a7fb5f69c483d9bf47f8b5e5acc3
http://europepmc.org/articles/PMC7229215
http://europepmc.org/articles/PMC7229215
Publikováno v:
ACS chemical neuroscience. 11(9)
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine (ser)/threonine (Thr) kinase that has been demonstrated to be one of the most functionally diverse kinases within neurons. Cdk5 is regulated via binding with its neuron-specific regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1260d701d2db8abd2c74e6a90873112
https://pubmed.ncbi.nlm.nih.gov/32286796
https://pubmed.ncbi.nlm.nih.gov/32286796
Publikováno v:
Future Medicinal Chemistry. 10:1399-1403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cfb0fc173902d43707fa3a2919db03
https://doi.org/10.4155/fmc-2018-0084
https://doi.org/10.4155/fmc-2018-0084
Autor:
Igor F. Tsigelny, Venkata Mahidhar Yenugonda, Valentina Fogal, Natsuko Nomura, Elmar Nurmemmedov, Ivan Babic, Santosh Kesari, Valentina L. Kouznetsova
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-12 (2017)
Journal of Translational Medicine
Journal of Translational Medicine
Background The mitochondrial protein p32 is a validated therapeutic target of cancer overexpressed in glioma. Therapeutic targeting of p32 with monoclonal antibody or p32-binding LyP-1 tumor-homing peptide can limit tumor growth. However, these agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365f5e39f4f1e13dcbabc005419ed18d
http://link.springer.com/article/10.1186/s12967-017-1312-7
http://link.springer.com/article/10.1186/s12967-017-1312-7
Publikováno v:
Cancer journal (Sudbury, Mass.). 25(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e34d09725f04f7ec1b19bc6511e0c8d
https://pubmed.ncbi.nlm.nih.gov/30896537
https://pubmed.ncbi.nlm.nih.gov/30896537