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pro vyhledávání: '"Venkata Bhaskar Rao Uppala"'
Autor:
Pratap Reddy Padi, Vishnuvardhan Sunkara, Venkata Bhaskar Rao Uppala, C. H. V. A. Sasikala, Pattabhi Ramayya, P. K. Dubey, Cherukupally Praveen
Publikováno v:
Organic Process Research & Development. 13:907-910
An efficient, cost-effective and large-scale synthesis of ezetimibe 1, an antihypercholesterolemia drug, is described. Chiral oxazolidinone chemistry was used to fix the required stereochemistry of the β-lactam ring, and the chiral oxazaborolidine c