Zobrazeno 1 - 1
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pro vyhledávání: '"Venkata Baratam"'
Autor:
Zhonghui Lu, James J.-W. Duan, Haiyun Xiao, James Neels, Dauh-Rurng Wu, Carolyn A. Weigelt, John S. Sack, Javed Khan, Max Ruzanov, Yongmi An, Melissa Yarde, Ananta Karmakar, Sureshbabu Vishwakrishnan, Venkata Baratam, Harisha Shankarappa, Sridhar Vanteru, Venkatesh Babu, Mushkin Basha, Arun Kumar Gupta, Selvakumar Kumaravel, Arvind Mathur, Qihong Zhao, Luisa M. Salter-Cid, Percy H. Carter, T.G. Murali Dhar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2265-2269
An X-ray crystal structure of one of our previously discovered RORγt inverse agonists bound to the RORγt ligand binding domain revealed that the cyclohexane carboxylic acid group of compound 2 plays a significant role in RORγt binding, forming fou