Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Venkata B. Nanduri"'
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. :56-60
Biocatalytic processes to selectively hydrolyze the N-carbobenzyloxy (CBz) group from CBz-protected d - or l -amino acids have been developed. The substrate specificities of the CBz-deprotecting enzymes from Burkholderia phenazinium SC 16530, and Sph
Publikováno v:
Enzyme and Microbial Technology. 39:1441-1450
The enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione (1) to either of the corresponding (S)- and (R)-6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decan
Autor:
Jianqing Li, Linda Chu, Venkata B. Nanduri, Atul S. Kotnis, William L. Parker, Richard H. Mueller, Ramesh N. Patel, Mark Liu
Publikováno v:
Tetrahedron: Asymmetry. 16:2778-2783
The enantioselective microbial reduction of 6-oxo-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione 1 to either of the corresponding (R)- or (S)-6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7
Autor:
Prasad J Siva, Linda Chu, Mary Jo Donovan, Ronald F Eiring, Robert J. Johnston, Richard H. Mueller, Ramesh N. Patel, Zhongping Shi, Junying Fan, Animesh Goswami, Brent Nielsen, Ambarish K. Singh, Kwok Y Wang, Dana L Cazzulino, Steven L. Goldberg, Weixuan He, Venkata B. Nanduri
Publikováno v:
Tetrahedron: Asymmetry. 15:1247-1258
The chiral intermediate ( S )-1-(2′-bromo-4′-fluoro phenyl)ethanol 2 was prepared by the enantioselective microbial reduction of 2-bromo-4-fluoro acetophenone 1 . Organisms from genus Candida , Hansenula , Pichia , Rhodotorula , Saccharomyces , S
Publikováno v:
Enzyme and Microbial Technology. 34:304-312
A novel enantioselective N-carbobenzyloxy (Cbz)-cleaving enzyme was purified to homogeneity from Sphingomonas paucimobilis SC 16113. The gene encoding the protein has been identified and its complete DNA sequence was determined. The Cbz-cleaving enzy
Publikováno v:
Advanced Synthesis & Catalysis. 345:830-834
A new enzymatic process for the enantioselective cleavage of N-benzyloxycarbonyl (Cbz) groups from protected amino acids and related compounds has been developed. The Cbz-deprotecting enzyme was isolated from cell extracts of Sphingomonas paucimobili
Autor:
Robert J. Johnston, Ramesh N. Patel, Ronald L. Hanson, Jeffrey M. Howell, Amit Banerjee, Rapheal Ko, Mary-Jo Donovan, Animesh Goswami, Dana L Cazzulino, Steven L. Goldberg, David B. Brzozowski, Venkata B. Nanduri, Thomas P. Tully
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 30:252-259
There has been an increasing awareness of the enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enatioselective manner. Chiral intermediates are in high demand by pharmaceutica
Autor:
Laporte Thomas L, John M. Wasylyk, Ronald L. Hanson, Ramesh N. Patel, Animesh Goswami, Kishta Katipally, Hyei-Jha Chung, Venkata B. Nanduri
Publikováno v:
Enzyme and Microbial Technology. 28:632-636
Three different biochemical approaches were used for the synthesis of ethyl 5-(S)-hydroxyhexanoate 1 and 5-(S)-hydroxyhexanenitrile 2. In the first approach, ethyl 5-oxo-hexanoate 3 and 5-oxo-hexanenitrile 4 were reduced by Pichia methanolica (SC 161
Publikováno v:
Tetrahedron: Asymmetry. 12:571-577
Phenylpyruvate decarboxylase from Achromobacter eurydice was used to catalyse the asymmetric acyloin condensation of phenylpyruvate 1 with various aldehydes 2 to produce optically active acyloins PhCH2COCH(OH)R 3. The specific activity of the phenylp
Publikováno v:
Journal of the American Oil Chemists' Society. 77:1015-1019
Chiral intermediates S-(+)-2-pentanol and S-(+)-2-heptanol were prepared by a lipase-catalyzed enzymatic resolution proces. Among various lipases evaluated for the stereoselective acylation of racemic alcohols, lipase B from Candida antarctica cataly