Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Venkata A. P. Chavali"'
Autor:
Kavita Praveen, Gaurang C. Patel, Lauren Gurski, Ariane H. Ayer, Trikaladarshi Persaud, Matthew D. Still, Lawrence Miloscio, Tavé Van Zyl, Silvio Alessandro Di Gioia, Ben Brumpton, Kristi Krebs, Bjørn Olav Åsvold, Esteban Chen, Venkata R. M. Chavali, Wen Fury, Harini V. Gudiseva, Sarah Hyde, Eric Jorgenson, Stephanie Lefebvre, Dadong Li, Alexander Li, James Mclninch, Brijeshkumar Patel, Jeremy S. Rabinowitz, Rebecca Salowe, Claudia Schurmann, Anne-Sofie Seidelin, Eli Stahl, Dylan Sun, Tanya M. Teslovich, Anne Tybjærg-Hansen, Cristen Willer, Scott Waldron, Sabrina Walley, Hua Yang, Sarthak Zaveri, Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration, Estonian Biobank Research Team, Ying Hu, Kristian Hveem, Olle Melander, Lili Milani, Stefan Stender, Joan M. O’Brien, Marcus B. Jones, Gonçalo R. Abecasis, Michael N. Cantor, Jonathan Weyne, Katia Karalis, Aris Economides, Giusy Della Gatta, Manuel A. Ferreira, George D. Yancopoulos, Aris Baras, Carmelo Romano, Giovanni Coppola
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Rare variant association data from human genetics combined with in vitro and in vivo functional validation highlight ANGPTL7 as a promising therapeutic target for intraocular pressure reduction, and protection from glaucoma.
Externí odkaz:
https://doaj.org/article/bf2cad284dd24cb3b77f0086f2b2543b
Autor:
Kevin R. Zhang, Connor S. R. Jankowski, Rayna Marshall, Rohini Nair, Néstor Más Gómez, Ahab Alnemri, Yingrui Liu, Elizabeth Erler, Julia Ferrante, Ying Song, Brent A. Bell, Bailey H. Baumann, Jacob Sterling, Brandon Anderson, Sierra Foshe, Jennifer Roof, Hossein Fazelinia, Lynn A. Spruce, Jen-Zen Chuang, Ching-Hwa Sung, Anuradha Dhingra, Kathleen Boesze-Battaglia, Venkata R. M. Chavali, Joshua D. Rabinowitz, Claire H. Mitchell, Joshua L. Dunaief
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/bef89837dcc1421d99a9a8707134f0ad
Autor:
Vrathasha Vrathasha, Sergei Nikonov, Brent Allen Bell, Jie He, Yajat Bungatavula, Katherine Elizabeth Uyhazi, Venkata Ramana Murthy Chavali
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105308- (2022)
Summary: Glaucoma is an optic neuropathy characterized by permanent visual field loss caused by the death of retinal ganglion cells (RGCs) and it is the leading cause of irreversible blindness worldwide. Consequently, there is an unmet need for the d
Externí odkaz:
https://doaj.org/article/641e0b6509c14ad4ae43083e5ad43501
Autor:
Raghavi Sudharsan, Leonardo Murgiano, Hsin-Yao Tang, Timothy W. Olsen, Venkata R. M. Chavali, Gustavo D. Aguirre, William A. Beltran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Prolactin (PRL) hormone functions as a pleiotropic cytokine with a protective role in the retina. We recently identified by transcriptome profiling that PRL is one of the most highly upregulated mRNAs in the retinas of mutant rcd1 (PDE6B) an
Externí odkaz:
https://doaj.org/article/7374429b174746bfb853812f0123472b
Autor:
Rebecca J Salowe, Roy Lee, Selam Zenebe-Gete, Marquis Vaughn, Harini V Gudiseva, Maxwell Pistilli, Ava Kikut, Emily Becker, David W Collins, Jie He, Sayaka Merriam, Kristen Mulvihill, Nora Laberee, Sara Lomax-Reese, Windell Murphy, Jeffrey Henderer, Venkata R M Chavali, Qi N Cui, Ahmara G Ross, Victoria Addis, Prithvi S Sankar, Eydie Miller-Ellis, Maureen G Maguire, Joan M O'Brien
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 8, p e0000416 (2022)
Genetic studies must enroll large numbers of participants to obtain adequate statistical power. Data are needed on how researchers can best use limited financial and practical resources to achieve these targets, especially in under-represented popula
Externí odkaz:
https://doaj.org/article/b802a01b6ce94bc0b0d9f5b720de9191
Autor:
Louise F. Porter, Neil Saptarshi, Yongxiang Fang, Sonika Rathi, Anneke I. den Hollander, Eiko K. de Jong, Simon J. Clark, Paul N. Bishop, Timothy W. Olsen, Triantafillos Liloglou, Venkata R. M. Chavali, Luminita Paraoan
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-14 (2019)
Abstract Background Age-related macular degeneration (AMD) is a degenerative disorder of the central retina and the foremost cause of blindness. The retinal pigment epithelium (RPE) is a primary site of disease pathogenesis. The genetic basis of AMD
Externí odkaz:
https://doaj.org/article/9aaee73b326e4404985a0a521687889e
Autor:
Venkata A P Chavali, Amit A. Deshmukh
Publikováno v:
International Journal of Electronics Letters. :1-10
Publikováno v:
Progress In Electromagnetics Research C. 130:1-14
Autor:
Nicholas N. Lyssenko, Naqi Haider, Antonino Picataggi, Eleonora Cipollari, Wanzhen Jiao, Michael C. Phillips, Daniel J. Rader, Venkata Ramana Murthy Chavali
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1927-1939 (2018)
Cholesterol-containing soft drusen and subretinal drusenoid deposits (SDDs) occur at the basolateral and apical side of the retinal pigment epithelium (RPE), respectively, in the chorioretina and are independent risk factors for late age-related macu
Externí odkaz:
https://doaj.org/article/82a8bc931c4a4aeab831b0af8eef13b0
Publikováno v:
IETE Journal of Research. :1-8