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pro vyhledávání: '"Venkat Reddy Sheri"'
Autor:
Heather L. Osswald, Hiroaki Mitsuya, Irene T. Weber, Venkat Reddy Sheri, Yuan-Fang Wang, Hironori Hayashi, Luke A. Kassekert, Arun K. Ghosh, Shujing Chen, Manabu Aoki, Johnson Agniswamy, Cuthbert D. Martyr
Publikováno v:
Journal of medicinal chemistry. 58(17)
Structure-based design, synthesis, and biological evaluation of a series of very potent HIV-1 protease inhibitors are described. In an effort to improve backbone ligand-binding site interactions, we have incorporated basic-amines at the C4 position o