Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Venkat K Ramshesh"'
Autor:
Yasodha Krishnasamy, Venkat K Ramshesh, Monika Gooz, Rick G Schnellmann, John J Lemasters, Zhi Zhong
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163342 (2016)
BACKGROUND AND AIM:Because ethanol consumption is commonly associated with a high cholesterol diet, we examined whether combined consumption of ethanol and high cholesterol increases liver injury and fibrosis. METHODS:Male C57BL/6J mice were fed diet
Externí odkaz:
https://doaj.org/article/639a8c05f88f465b82ac6fbb85f579cf
Autor:
Zhi Zhong, Venkat K Ramshesh, Hasibur Rehman, Qinlong Liu, Tom P Theruvath, Yasodha Krishnasamy, John J Lemasters
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91308 (2014)
An increase of ethanol metabolism and hepatic mitochondrial respiration occurs in vivo after a single binge of alcohol. Here, our aim was to determine how ethanol intake affects hepatic mitochondrial polarization status in vivo in relation to ethanol
Externí odkaz:
https://doaj.org/article/f2ba8228ba414d938af4c0bc8bd1186c
Autor:
Venkat K, Ramshesh, John J, Lemasters
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1782
Laser scanning confocal microscopy provides the ability to image submicron sections in living cells and tissues. In conjunction with pH-indicating fluorescent probes, confocal microscopy can be used to visualize the distribution of pH inside living c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1834e65f0a7dd4dbcdf119d6276cd40a
https://pubmed.ncbi.nlm.nih.gov/29851011
https://pubmed.ncbi.nlm.nih.gov/29851011
Publikováno v:
Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3588187e85c6a9d6d73527c3a0f889a2
https://doi.org/10.1002/9781119329725.ch28
https://doi.org/10.1002/9781119329725.ch28
Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire
Autor:
Thomas L. Dawson, John Soon Yew Lim, Gregory L. Lovelace, John J. Lemasters, Graham D. Wright, Venkat K. Ramshesh, Duane P. Harland
Publikováno v:
Journal of Investigative Dermatology.
Little is known about the energetics of growing hair follicles, particularly in the mitochondrially abundant bulb. Here, mitochondrial and oxidative metabolism was visualized by multiphoton and light sheet microscopy in cultured bovine hair follicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f757f5e2eaf73f831746e6ba2279b6a4
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 150(1)
Acetaminophen (APAP) overdose causes hepatotoxicity involving mitochondrial dysfunction and c-jun N-terminal kinase (JNK) activation. Because the safe limit of APAP dosing is controversial, our aim was to evaluate the role of the mitochondrial permea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a81bc792b6d719eaaf01639a250f721
https://pubmed.ncbi.nlm.nih.gov/26721299
https://pubmed.ncbi.nlm.nih.gov/26721299
Autor:
Monika Gooz, Venkat K. Ramshesh, Rick G. Schnellmann, Zhi Zhong, John J. Lemasters, Yasodha Krishnasamy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0163342 (2016)
PLoS ONE, Vol 11, Iss 9, p e0163342 (2016)
Background and Aim Because ethanol consumption is commonly associated with a high cholesterol diet, we examined whether combined consumption of ethanol and high cholesterol increases liver injury and fibrosis. Methods Male C57BL/6J mice were fed diet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c0047f0db1ddb063b0f5bf411c2155
https://pubmed.ncbi.nlm.nih.gov/27676640
https://pubmed.ncbi.nlm.nih.gov/27676640
Autor:
Hasibur, Rehman, Qinlong, Liu, Yasodha, Krishnasamy, Zengdun, Shi, Venkat K, Ramshesh, Khujista, Haque, Rick G, Schnellmann, Michael P, Murphy, John J, Lemasters, Don C, Rockey, Zhi, Zhong
Publikováno v:
International journal of physiology, pathophysiology and pharmacology. 8(1)
Oxidative stress plays an essential role in liver fibrosis. This study investigated whether MitoQ, an orally active mitochondrial antioxidant, decreases liver fibrosis. Mice were injected with corn oil or carbon tetrachloride (CCl4, 1:3 dilution in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0f26e1bd90a0c207e700ae77d1b37f1
https://pubmed.ncbi.nlm.nih.gov/27186319
https://pubmed.ncbi.nlm.nih.gov/27186319
Autor:
Venkat K. Ramshesh, R. David Sentelle, Zdzislaw M. Szulc, Salih Gencer, Wenhui Jiang, Can E. Senkal, Shanmugam Panneer Selvam, Yuri K. Peterson, Jacek Bielawski, Suriyan Ponnusamy, John J. Lemasters, Besim Ogretmen
Publikováno v:
Nature chemical biology
Mechanisms by which autophagy promotes cell survival or death are unclear. We provide evidence that C(18)-pyridinium ceramide treatment or endogenous C(18)-ceramide generation by ceramide synthase 1 (CerS1) expression mediates autophagic cell death,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcea2fd9751c8cbde39a599aacfbf49
https://doi.org/10.1038/nchembio.1059
https://doi.org/10.1038/nchembio.1059
Autor:
Yasodha Krishnasamy, Venkat K. Ramshesh, Kenneth D. Chavin, Qinlong Liu, Hasibur Rehman, Tom P. Theruvath, Zhi Zhong, Rick G. Schnellmann, John J. Lemasters
Publikováno v:
Free Radical Biology and Medicine. 53:250-259
This study investigated the role of inducible nitric oxide synthase (iNOS) in failure of ethanol-induced fatty liver grafts. Rat livers were explanted 20 h after gavaging with ethanol (5 g/kg) and storing in UW solution for 24 h before implantation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a18dd1c743b2668f35f2844e3c4127
https://doi.org/10.1016/j.freeradbiomed.2012.05.012
https://doi.org/10.1016/j.freeradbiomed.2012.05.012