Systolic [Ca2+]i regulates diastolic levels in rat ventricular myocytes

Autor: Sankaranarayanan, R, Kistamas, K, Greensmith, DJ, Venetucci, LA, Eisner, DA

Publikováno v: Sankaranarayanan, R, Kistamas, K, Greensmith, DJ, Venetucci, L & Eisner, D 2017, ' Systolic [Ca 2+ ] i regulates diastolic levels in rat ventricular myocytes. ', The Journal of Physiology, vol. 595, no. 16, pp. 5545-5555 . https://doi.org/10.1113/JP274366

[Ca2+]i must be low enough in diastole so that the ventricle is relaxed and can refill with blood. Interference with this will impair relaxation. The factors responsible for regulation of diastolic [Ca2+]i, in particular the relative roles of the sar

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https://www.research.manchester.ac.uk/portal/en/publications/systolic-ca2i-regulates-diastolic-levels-in-rat-ventricular-myocytes(34a0ffe3-4017-4ae1-9956-862a5ed47de3).html

Author Correction: Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia.

Autor: Hayter EA; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Wehrens SMT; Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK., Van Dongen HPA; Sleep and Performance Research Center, Washington State University, Spokane, WA, USA.; Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA., Stangherlin A; MRC Laboratory of Molecular Biology, Cambridge, UK., Gaddameedhi S; Department of Biological Sciences, Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA., Crooks E; Sleep and Performance Research Center, Washington State University, Spokane, WA, USA.; Department of Physical Therapy, Eastern Washington University, Spokane, WA, USA., Barron NJ; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Venetucci LA; Unit of Clinical Physiology, Manchester Academic Health Science Centre, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., O'Neill JS; MRC Laboratory of Molecular Biology, Cambridge, UK., Brown TM; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Skene DJ; Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK., Trafford AW; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Unit of Clinical Physiology, Manchester Academic Health Science Centre, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Bechtold DA; Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. David.bechtold@manchester.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2021 Dec 08; Vol. 12 (1), pp. 7284. Date of Electronic Publication: 2021 Dec 08.

Flecainide and antiarrhythmic effects in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

Autor: Liu N; Cardiovascular Genetic Program, The Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY 10016, USA., Napolitano C, Venetucci LA, Priori SG

Publikováno v: Trends in cardiovascular medicine [Trends Cardiovasc Med] 2012 Feb; Vol. 22 (2), pp. 35-9. Date of Electronic Publication: 2012 Aug 04.

How does CaMKIIdelta phosphorylation of the cardiac ryanodine receptor contribute to inotropy?

Autor: Eisner DA, George CH, Smith GL, Trafford AW, Venetucci LA

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Aug 03; Vol. 107 (31), pp. E123; author reply E124. Date of Electronic Publication: 2010 Jul 21.

What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis?

Autor: Eisner DA; Unit of Cardiac Physiology, University of Manchester, 3.18 Core Technology Facility, Manchester, UK. Eisner@man.ac.uk, Kashimura T, O'Neill SC, Venetucci LA, Trafford AW

Publikováno v: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2009 Apr; Vol. 46 (4), pp. 474-81. Date of Electronic Publication: 2008 Dec 25.