Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Venetta Thomas"'
Autor:
Fang Chen, Jing He, Jianqi Zhang, Gary K Chen, Venetta Thomas, Christine B Ambrosone, Elisa V Bandera, Sonja I Berndt, Leslie Bernstein, William J Blot, Qiuyin Cai, John Carpten, Graham Casey, Stephen J Chanock, Iona Cheng, Lisa Chu, Sandra L Deming, W Ryan Driver, Phyllis Goodman, Richard B Hayes, Anselm J M Hennis, Ann W Hsing, Jennifer J Hu, Sue A Ingles, Esther M John, Rick A Kittles, Suzanne Kolb, M Cristina Leske, Robert C Millikan, Kristine R Monroe, Adam Murphy, Barbara Nemesure, Christine Neslund-Dudas, Sarah Nyante, Elaine A Ostrander, Michael F Press, Jorge L Rodriguez-Gil, Ben A Rybicki, Fredrick Schumacher, Janet L Stanford, Lisa B Signorello, Sara S Strom, Victoria Stevens, David Van Den Berg, Zhaoming Wang, John S Witte, Suh-Yuh Wu, Yuko Yamamura, Wei Zheng, Regina G Ziegler, Alexander H Stram, Laurence N Kolonel, Loïc Le Marchand, Brian E Henderson, Christopher A Haiman, Daniel O Stram
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131106 (2015)
Height has an extremely polygenic pattern of inheritance. Genome-wide association studies (GWAS) have revealed hundreds of common variants that are associated with human height at genome-wide levels of significance. However, only a small fraction of
Externí odkaz:
https://doaj.org/article/128e46a0c8c94ba998a6a6c96bfe5c2f
Autor:
Iona Cheng, Stephen Watya, Anna M. Ray, Timothy R. Rebbeck, Kristine R. Monroe, John S. Witte, Sara S. Strom, Yuko Yamamura, John D. Carpten, Brian E. Henderson, Ann W. Hsing, Janet L. Stanford, Peggy Wan, M. Cristina Leske, Edder R. Duarte, Sonja I. Berndt, Loreall Pooler, William J. Blot, Charnita Zeigler-Johnson, Zhaoming Wang, Venetta Thomas, Stephen J. Chanock, David Van Den Berg, W. Ryan Diver, Richard B. Hayes, Michael J. Thun, Graham Casey, Benjamin A. Rybicki, Christopher A. Haiman, Sue A. Ingles, Bao Li Chang, Jennifer J. Hu, Kathleen A. Cooney, Qiuyin Cai, Barbara Nemesure, Loic Le Marchand, William B. Isaacs, Gary K. Chen, Jennifer Haslag-Minoff, Esther M. John, S. Lilly Zheng, Glenn O. Allen, Xin Sheng, Suh Yuh Wu, Laurence N. Kolonel, Erin N. Carter, Elaine A. Ostrander, Christine Neslund-Dudas, Suzanne Kolb, Lisa B. Signorello, Yao Tettey, Adam B. Murphy, Rick A. Kittles, Jianfeng Xu, Fredrick R. Schumacher, William Wu, Lucy Xia, Adam S. Kibel, Daniel O. Stram, Anselm Hennis, Edward D. Yeboah, Serigne Magueye Gueye
Publikováno v:
Nature genetics
In search of common risk alleles for prostate cancer that could contribute to high rates of the disease in men of African ancestry, we conducted a genome-wide association study, with 1,047,986 SNP markers examined in 3,425 African-Americans with pros
Publikováno v:
Infection and Immunity. 76:4905-4912
Anaplasma phagocytophilum, a gram-negative obligate intracellular pathogen, has a tropism for neutrophils and their precursors. The resulting disease, human granulocytic anaplasmosis, is often characterized by fever, severe headache, malaise, myalgia
Autor:
Renu Garg, Venetta Thomas, Ashish, Mercedes Rincon, Erol Fikrig, Joanna K. Krueger, Juan Anguita, Shobana K. Ananthanarayanan, Ignacio J. Juncadella, Nandhini Ramamoorthi, Christopher M. Yengo
Publikováno v:
The Journal of Immunology. 177:6579-6583
Salp15 is an Ixodes scapularis salivary protein that inhibits CD4+ T cell activation through the repression of TCR ligation-triggered calcium fluxes and IL-2 production. We show in this study that Salp15 binds specifically to the CD4 coreceptor on ma
Publikováno v:
Infection and Immunity. 73:208-218
Infection of neutrophil precursors withAnaplasma phagocytophilum, the causative agent of human granulocytic ehrlichiosis, results in downregulation of the gp91phoxgene, a key component of NADPH oxidase. We now show that repression of gp91phoxgene tra
Autor:
Erol Fikrig, Venetta Thomas
Publikováno v:
Vector-Borne and Zoonotic Diseases. 2:217-222
Vaccination with Borrelia burgdorferi outer surface protein (Osp) A can induce a protective response against Lyme disease and serves as a model to understand the generation of protective immune responses against the spirochete. The innate response to
Autor:
Venetta Thomas, Erol Fikrig, Mercedes Rincon, Rafal Persinski, Dietrich Conze, Philip W. Askenase, Subrata Das, Joppe W. Hovius, Nandhini Ramamoorthi, Fred S. Kantor, Juan Anguita
Publikováno v:
Immunity, 16(6), 849-859. Cell Press
Tick saliva has pleiotropic properties that facilitate persistence of the arthropod upon the host. We now describe a feeding-inducible protein in Ixodes scapularis saliva, Salp15, that inhibits CD4+ T cell activation. The mechanism involves the repre
Autor:
Juan Anguita, Rafal Persinski, Swapna Samanta, Venetta Thomas, Carmen Hernanz, Stephen W. Barthold, Erol Fikrig
Publikováno v:
The Journal of Immunology. 167:3383-3390
Spirochete adaptation in vivo is associated with preferential Borrelia burgdorferi gene expression. In this paper, we show that the administration of B. burgdorferi-immune sera to IFN-γR-deficient mice that have been infected with B. burgdorferi N40
Publikováno v:
Journal of Neuroimmunology. 70:199-206
The intracellular signaling pathways responsible for tumor necrosis factor (TNF)-alpha stimulation of lymphocyte adhesion to brain microvascular endothelial cells (BMEC) were studied using inhibitors of protein kinase C (bisindolylmaleimide HCl, H-7,
Autor:
Juan Anguita, Venetta Thomas, Swapna Samanta, Philip E. Stewart, Stephen W. Barthold, Patricia A. Rosa, Erol Fikrig
Publikováno v:
Infection and Immunity. 69:3507-3509
Clonal Borrelia burgdorferi N40 (cN40) passaged 75 times in vitro (N40-75) infects mice but does not cause disease. N40-75 passaged 45 times further in vitro (N40-120) was no longer infectious and lacked genes encoded on linear plasmids 38 and 28-1,