Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vendula Novosadová"'
Autor:
Michaela Šímová, Carlos Eduardo Madureira Trufen, Iva Šplíchalová, Jan Kubovčiak, Michal Kolář, Vendula Novosadová, Jan Procházka, Dominik Filipp, Radislav Sedláček, Jana Balounová
Publikováno v:
HemaSphere, Vol 7, p e2843053 (2023)
Externí odkaz:
https://doaj.org/article/4e20b105a8114812b51812c9b1ab3fc7
Autor:
Barbora Pokrývková, Martina Saláková, Jana Šmahelová, Zuzana Vojtěchová, Vendula Novosadová, Ruth Tachezy
Publikováno v:
Viruses, Vol 12, Iss 1, p 42 (2019)
The human papillomavirus (HPV) integration, the critical step in viral carcinogenesis, most frequently occurs in the E2 gene, which results in its inactivation and in an increase of E6/E7 transcription. However, in a substantial number of tumors, the
Externí odkaz:
https://doaj.org/article/56e5208207c34444867f94c5c9f527eb
Autor:
Philipp Kunze, Lucas Kreiss, Vendula Novosadová, Adriana V. Roehe, Sara Steinmann, Jan Prochazka, Carol I. Geppert, Arndt Hartmann, Sebastian Schürmann, Oliver Friedrich, Regine Schneider-Stock
Publikováno v:
Cancers; Volume 14; Issue 10; Pages: 2364
Simple Summary The formation of metastasis is not only intricately orchestrated by cancer cells but is also affected by the surrounding extracellular matrix (ECM). The barrier function of the ECM represents an obstacle that cancer cells have to overc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa0642eb93bd7c7c8f9fbf4a8d8edac
https://pubmed.ncbi.nlm.nih.gov/35625969
https://pubmed.ncbi.nlm.nih.gov/35625969
Autor:
Jan Benes, Katerina Kroupova, Martin Kotrc, Jiri Petrak, Petr Jarolim, Vendula Novosadova, Josef Kautzner, Vojtech Melenovsky
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract There is no biomarker reflecting right ventricular dysfunction in HFrEF patients used in clinical practice. We have aimed to look for a circulating marker of RV dysfunction employing a quantitative proteomic strategy. The Olink Proteomics Mu
Externí odkaz:
https://doaj.org/article/126dcc6c0c7c44c7964fad0be6c919ae
Autor:
Frantisek Spoutil, Goretti Aranaz-Novaliches, Michaela Prochazkova, Tomas Wald, Vendula Novosadova, Petr Kasparek, Radim Osicka, Janne E. Reseland, Staale P. Lyngstadaas, Hanna Tiainen, Kristyna Bousova, Jiri Vondrasek, Radislav Sedlacek, Jan Prochazka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Highly specialized enamel matrix proteins (EMPs) are predominantly expressed in odontogenic tissues and diverged from common ancestral gene. They are crucial for the maturation of enamel and its extreme complexity in multiple independent lin
Externí odkaz:
https://doaj.org/article/9cee86c6099c4e5593b71dbfde9ce7ab
Autor:
Veronika Iatsiuk, Frantisek Malinka, Marketa Pickova, Jolana Tureckova, Jiri Klema, Frantisek Spoutil, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Ubiquitin ligases (Ub-ligases) are essential intracellular enzymes responsible for the regulation of proteome homeostasis, signaling pathway crosstalk, cell differentiation and stress responses. Individual Ub-ligases exhibit their
Externí odkaz:
https://doaj.org/article/e558a3d0012143f19359d963650b887f
Autor:
Eliska Vacurova, Jaroslava Trnovska, Petr Svoboda, Vojtech Skop, Vendula Novosadova, David Pajuelo Reguera, Silvia Petrezselyová, Benoit Piavaux, Berwini Endaya, Frantisek Spoutil, Dagmar Zudova, Jan Stursa, Magdalena Melcova, Zuzana Bielcikova, Lukas Werner, Jan Prochazka, Radislav Sedlacek, Martina Huttl, Sona Stemberkova Hubackova, Martin Haluzik, Jiri Neuzil
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Senescent cells play a role in pathogenesis of diabetes, and senolytic agents can improve obesity- and diabetes-related pathologies. Here the authors report that mitochondrially targeted tamoxifen, a potential anti-cancer agent with senolytic activit
Externí odkaz:
https://doaj.org/article/e1a97d3a7b444e588a78bce984149ca2
Autor:
Pilar Cacheiro, Violeta Muñoz-Fuentes, Stephen A. Murray, Mary E. Dickinson, Maja Bucan, Lauryl M. J. Nutter, Kevin A. Peterson, Hamed Haselimashhadi, Ann M. Flenniken, Hugh Morgan, Henrik Westerberg, Tomasz Konopka, Chih-Wei Hsu, Audrey Christiansen, Denise G. Lanza, Arthur L. Beaudet, Jason D. Heaney, Helmut Fuchs, Valerie Gailus-Durner, Tania Sorg, Jan Prochazka, Vendula Novosadova, Christopher J. Lelliott, Hannah Wardle-Jones, Sara Wells, Lydia Teboul, Heather Cater, Michelle Stewart, Tertius Hough, Wolfgang Wurst, Radislav Sedlacek, David J. Adams, John R. Seavitt, Glauco Tocchini-Valentini, Fabio Mammano, Robert E. Braun, Colin McKerlie, Yann Herault, Martin Hrabě de Angelis, Ann-Marie Mallon, K. C. Kent Lloyd, Steve D. M. Brown, Helen Parkinson, Terrence F. Meehan, Damian Smedley, The Genomics England Research Consortium, The International Mouse Phenotyping Consortium
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Discovery of causal variants for monogenic disorders has been facilitated by whole exome and genome sequencing, but does not provide a diagnosis for all patients. Here, the authors propose a Full Spectrum of Intolerance to Loss-of-Function (FUSIL) ca
Externí odkaz:
https://doaj.org/article/38973450f49d45729ee9836b3968bc61
Autor:
Branislav Kovacech, Lubica Fialova, Peter Filipcik, Rostislav Skrabana, Monika Zilkova, Natalia Paulenka-Ivanovova, Andrej Kovac, Denisa Palova, Gabriela Paulikova Rolkova, Katarina Tomkova, Natalia Turic Csokova, Karina Markova, Michaela Skrabanova, Kristina Sinska, Neha Basheer, Petra Majerova, Jozef Hanes, Vojtech Parrak, Michal Prcina, Ondrej Cehlar, Martin Cente, Juraj Piestansky, Michal Fresser, Michal Novak, Monika Slavikova, Kristina Borsova, Viktoria Cabanova, Bronislava Brejova, Tomas Vinař, Jozef Nosek, Boris Klempa, Ludek Eyer, Vaclav Hönig, Martin Palus, Daniel Ruzek, Tereza Vyhlidalova, Petra Strakova, Blanka Mrazkova, Dagmar Zudova, Gizela Koubkova, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek, Norbert Zilka, Eva Kontsekova
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103818- (2022)
Summary: Background: The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) and B.1.617.2 (Delta) that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic
Externí odkaz:
https://doaj.org/article/d503988bb92a4f8ca2f39b041da95550
Autor:
Klara Cervena, Vendula Novosadova, Barbara Pardini, Alessio Naccarati, Alena Opattova, Josef Horak, Sona Vodenkova, Tomas Buchler, Pavel Skrobanek, Miroslav Levy, Pavel Vodicka, Veronika Vymetalkova
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
MicroRNAs (miRNAs) regulate gene expression in a tissue-specific manner. However, little is known about the miRNA expression changes induced by the therapy in rectal cancer (RC) patients. We evaluated miRNA expression levels before and after therapy
Externí odkaz:
https://doaj.org/article/0fce0d73d1a041b9ac949c865103fdbc