A Plasmodium falciparum genetic cross reveals the contributions of pfcrt and plasmepsin II/III to piperaquine drug resistance.

Autor: Kane J; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Li X; Disease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, Texas, USA., Kumar S; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Button-Simons KA; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Vendrely Brenneman KM; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Dahlhoff H; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Sievert MAC; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Checkley LA; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Shoue DA; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Singh PP; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA., Abatiyow BA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Haile MT; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Nair S; Disease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, Texas, USA., Reyes A; Disease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, Texas, USA., Tripura R; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building, University of Oxford Old Road Campus, Oxford, United Kingdom., Peto TJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building, University of Oxford Old Road Campus, Oxford, United Kingdom., Lek D; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.; School of Public Health, National Institute of Public Health, Phnom Penh, Cambodia., Mukherjee A; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA.; Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana, USA., Kappe SHI; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Pediatrics, University of Washington, Seattle, Washington, USA., Dhorda M; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building, University of Oxford Old Road Campus, Oxford, United Kingdom., Nkhoma SC; BEI Resources, American Type Culture Collection (ATCC), Manassas, Virginia, USA., Cheeseman IH; Host Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, Texas, USA., Vaughan AM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Pediatrics, University of Washington, Seattle, Washington, USA., Anderson TJC; Disease Intervention and Prevention Program, Texas Biomedical Research Institute, San Antonio, Texas, USA., Ferdig MT; Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA.

Publikováno v: MBio [mBio] 2024 Jul 17; Vol. 15 (7), pp. e0080524. Date of Electronic Publication: 2024 Jun 24.