Gamma crystallins of the human eye lens.

Autor: Vendra VP; Ophthalmic Molecular Genetics Section, National Eye Institute, Building 5635FL, Room 1S24, 5625 Fishers Lane, Rockville, MD 20852, United States. Electronic address: pullaraovv@gmail.com., Khan I; Prof. Brien Holden Eye Research Centre, Hyderabad Eye Research Foundation, L. V. Prasad Eye Institute, Hyderabad 500034 Telangana, India. Electronic address: ismailkhan.hcu@gmail.com., Chandani S; Plot 32, LIC Colony, W Marredpally, Secunderabad 500026, Telangana, India. Electronic address: sushilchandani@gmail.com., Muniyandi A; Department of Animal Science, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India. Electronic address: anbu.blessings@gmail.com., Balasubramanian D; Prof. Brien Holden Eye Research Centre, Hyderabad Eye Research Foundation, L. V. Prasad Eye Institute, Hyderabad 500034 Telangana, India. Electronic address: dbala@lvpei.org.

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2016 Jan; Vol. 1860 (1 Pt B), pp. 333-43. Date of Electronic Publication: 2015 Jun 25.

Structural integrity of the Greek key motif in βγ-crystallins is vital for central eye lens transparency.

Autor: Vendra VP; Hyderabad Eye Research Foundation, LV Prasad Eye Institute, Hyderabad, India., Agarwal G, Chandani S, Talla V, Srinivasan N, Balasubramanian D

Publikováno v: PloS one [PLoS One] 2013 Aug 06; Vol. 8 (8), pp. e70336. Date of Electronic Publication: 2013 Aug 06 (Print Publication: 2013).

The mutation V42M distorts the compact packing of the human gamma-S-crystallin molecule, resulting in congenital cataract.

Autor: Vendra VP; Prof. Brien Holden Eye Research Centre, Hyderabad Eye Research Foundation, LV Prasad Eye Institute, Hyderabad, India., Chandani S, Balasubramanian D

Publikováno v: PloS one [PLoS One] 2012; Vol. 7 (12), pp. e51401. Date of Electronic Publication: 2012 Dec 21.