Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Veluchamy, Amutha Barathi"'
Autor:
Liqin Jiang, James H. Z. Koh, Sherlyn H. Y. Seah, Yee Shan Dan, Zhaoran Wang, Xavier Chan, Lei Zhou, Veluchamy Amutha Barathi, Quan V. Hoang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The mechanisms underlying myopia pathogenesis are not well understood. Using publicly-available human and animal datasets, we expound on the roles of known, implicated proteins, and new myopia-related signaling pathways were hypothesized. Pr
Externí odkaz:
https://doaj.org/article/92e662d15eec45e7a5637e7a1f870f3c
Autor:
Bingyao Tan, Huakun Li, Yueming Zhuo, Le Han, Rajeshkumar Mupparapu, Davide Nanni, Veluchamy Amutha Barathi, Daniel Palanker, Leopold Schmetterer, Tong Ling
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Phototransduction involves changes in concentration of ions and other solutes within photoreceptors and in subretinal space, which affect osmotic pressure and the associated water flow. Corresponding expansion and contraction of cellular lay
Externí odkaz:
https://doaj.org/article/c6b9acc96a914dba98d5a3a957945455
Autor:
Erfan Rezvani Ghomi, Venkatesh Mayandi, Vijila Chellappan, Nileshkumar Dubey, Kottaiswamy Amuthavalli, Rasoul Esmaeely Neisiany, Veluchamy Amutha Barathi, Navin Kumar Verma, Rajamani Lakshminarayanan, Seeram Ramakrishna
Publikováno v:
Materials & Design, Vol 238, Iss , Pp 112694- (2024)
Diabetic ulcers remain a significant challenge in wound care due to loss of epithelial cell migration. Aligned nanofibrous scaffolds mimicking the skin's extracellular matrix (ECM) are promising candidates for diabetic wound healing. In this study, a
Externí odkaz:
https://doaj.org/article/aa0be1331665464b90316f18fe6bc1ed
Autor:
Bhav Harshad Parikh, Zengping Liu, Paul Blakeley, Qianyu Lin, Malay Singh, Jun Yi Ong, Kim Han Ho, Joel Weijia Lai, Hanumakumar Bogireddi, Kim Chi Tran, Jason Y. C. Lim, Kun Xue, Abdurrahmaan Al-Mubaarak, Binxia Yang, Sowmiya R, Kakkad Regha, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Zhongxing Zhang, Anand D. Jeyasekharan, Veluchamy Amutha Barathi, Weimiao Yu, Kang Hao Cheong, Timothy A. Blenkinsop, Walter Hunziker, Gopal Lingam, Xian Jun Loh, Xinyi Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
One common cause of vision loss after retinal detachment surgery is retinal scarring. Here the authors demonstrate that a bio-functional polymer can prevent retinal scarring by suppression of epithelial-mesenchymal transition and hyper-proliferation
Externí odkaz:
https://doaj.org/article/29658a3e9704480d80f0623a65432050
Autor:
Darren Shu Jeng Ting, Eunice Tze Leng Goh, Venkatesh Mayandi, Joanna M. F. Busoy, Thet Tun Aung, Mercy Halleluyah Periayah, Mario Nubile, Leonardo Mastropasqua, Dalia G. Said, Hla M. Htoon, Veluchamy Amutha Barathi, Roger W. Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S. Dua
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to develop a novel class of antimicrobial therapy, based on human-derived hybrid host defense peptides (HyHDPs), for treating BK. HyHDPs were rationall
Externí odkaz:
https://doaj.org/article/b8964e8c144045dd99c424d45d86d9a4
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1045 (2023)
Myopia, a prevalent refractive error disorder worldwide, is characterized by the elongation of the eye, leading to visual abnormalities. Understanding the genetic factors involved in myopia is crucial for developing therapeutic and preventive measure
Externí odkaz:
https://doaj.org/article/6049c63c4f1b4ebe833950dd2afd44e5
Autor:
Swathi Lingam, Zengping Liu, Binxia Yang, Wendy Wong, Bhav Harshad Parikh, Jun Yi Ong, Debbie Goh, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Gavin S. W. Tan, Graham E. Holder, Kakkad Regha, Veluchamy Amutha Barathi, Walter Hunziker, Gopal Lingam, Xianmin Zeng, Xinyi Su
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Retinal regenerative therapies hold great promise for the treatment of inherited retinal degenerations (IRDs). Studies in preclinical lower mammal models of IRDs have suggested visual improvement following retinal photoreceptor pr
Externí odkaz:
https://doaj.org/article/ebb00a72f8324335bf6cabbb07433c97
Autor:
Zengping Liu, Tanja Ilmarinen, Gavin S. W. Tan, Heidi Hongisto, Edmund Y. M. Wong, Andrew S. H. Tsai, Sami Al-Nawaiseh, Graham E. Holder, Xinyi Su, Veluchamy Amutha Barathi, Heli Skottman, Boris V. Stanzel
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Human pluripotent stem cells (hPSCs) provide a promising cell source for retinal cell replacement therapy but often lack standardized cell production and live-cell shipment logistics as well as rigorous analyses of surgical proced
Externí odkaz:
https://doaj.org/article/79af98e8d625467a8668cca14fc1c485
Autor:
Venkatesh Mayandi, Wen-Tyng Kang, Darren Shu Jeng Ting, Eunice Tze Leng Goh, Myoe Naing Lynn, Thet Tun Aung, Jamuna Vadivelu, Veluchamy Amutha Barathi, Anita Sook Yee Chan, Rajamani Lakshminarayanan
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1044 (2023)
The effectiveness of current antifungal therapies is hampered by the emergence of drug resistance strains, highlighting an urgent need for new alternatives such as adjuvant antifungal treatments. This study aims to examine the synergism between propr
Externí odkaz:
https://doaj.org/article/343ac341d3614defaaa57811714693e2
Autor:
Liqin Jiang, Dong Xuan Goh, James Hao Zhong Koh, Xavier Chan, Noel A. Brennan, Veluchamy Amutha Barathi, Quan V. Hoang
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 494 (2023)
Myopia is a globally emerging concern accompanied by multiple medical and socio-economic burdens with no well-established causal treatment to control thus far. The study of the genomics and transcriptomics of myopia treatment is crucial to delineate
Externí odkaz:
https://doaj.org/article/a4676dd42049490dae6eaafc5470279f