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Akademický článek

Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy

Autor: Han Byung, Zhou Meng-liang, Vellimana Ananth K, Milner Eric, Kim David H, Greenberg Jacob K, Chu Wenhua, Mach Robert H, Zipfel Gregory J

Publikováno v: Molecular Neurodegeneration, Vol 6, Iss 1, p 86 (2011)

Abstract Background Cerebral amyloid angiopathy (CAA) is characterized by deposition of fibrillar amyloid β (Aβ) within cerebral vessels. It is commonly seen in the elderly and almost universally present in patients with Alzheimer's Disease (AD). I

Externí odkaz: https://doaj.org/article/e56c23361e7b42a59cf2df288e65f9b7

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Akademický článek

Non-invasive Auricular Vagus nerve stimulation for Subarachnoid Hemorrhage (NAVSaH): Protocol for a prospective, triple-blinded, randomized controlled trial.

Autor: Anna Huguenard, Gansheng Tan, Gabrielle Johnson, Markus Adamek, Andrew Coxon, Terrance Kummer, Joshua Osbun, Ananth Vellimana, David Limbrick, Gregory Zipfel, Peter Brunner, Eric Leuthardt

Publikováno v: PLoS ONE, Vol 19, Iss 8, p e0301154 (2024)

BackgroundInflammation has been implicated in driving the morbidity associated with subarachnoid hemorrhage (SAH). Despite understanding the important role of inflammation in morbidity following SAH, there is no current effective way to modulate this

Externí odkaz: https://doaj.org/article/252be2a51ace46f1ab7f7f35438b8fbf

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Akademický článek

Darkness and Death in the U.S.: Walking Distances Across the Nation by Time of Day and Time of Year

Autor: Maithreyi Vellimana, Kara Kockelman

Publikováno v: Findings (2023)

This paper examines walk distances across the United States by time of day and year, using data from the National Household Travel Survey 2016/2017, to understand factors contributing to higher pedestrian deaths at night across various states. Hurdle

Externí odkaz: https://doaj.org/article/3a4e8a9644314c249e1b574904cbb2ec

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Akademický článek

Isoflurane Conditioning‐Induced Delayed Cerebral Ischemia Protection in Subarachnoid Hemorrhage—Role of Inducible Nitric Oxide Synthase

Autor: Meizi Liu, Keshav Jayaraman, Aaron J. Norris, Ahmed Hussein, James W. Nelson, Jogender Mehla, Deepti Diwan, Ananth Vellimana, Yousef Abu‐Amer, Gregory J. Zipfel, Umeshkumar Athiraman

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)

Background Recent evidence implicates inflammation as a key driver in delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage (SAH). Inducible nitric oxide synthase (iNOS) is one of the known major mediators of inflammation. We previously

Externí odkaz: https://doaj.org/article/bdf8c2085ff84924a699b42cb9ad5e00

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Akademický článek

Surgery for Pituitary Tumor Apoplexy Is Associated with Rapid Headache and Cranial Nerve Improvement

Autor: Kevin A. Cross, Rupen Desai, Ananth Vellimana, Yupeng Liu, Keith Rich, Gregory Zipfel, Ralph Dacey, Michael Chicoine, Cristine Klatt-Cromwell, Jonathan McJunkin, Patrik Pipkorn, John S. Schneider, Julie Silverstein, Albert H. Kim

Publikováno v: Current Oncology, Vol 29, Iss 7, Pp 4914-4922 (2022)

Pituitary tumor apoplexy (PTA) classically comprises sudden-onset headache, loss of vision, ophthalmoparesis, and decreased consciousness. It typically results from hemorrhage and/or infarction within a pituitary adenoma. Presentation is heterologous

Externí odkaz: https://doaj.org/article/292028a8b2ea49dfb42bcba8c5bf645c

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Akademický článek

A review of technological innovations leading to modern endovascular brain aneurysm treatment

Autor: David C. Lauzier, Anna L. Huguenard, Anja I. Srienc, Samuel J. Cler, Joshua W. Osbun, Arindam R. Chatterjee, Ananth K. Vellimana, Akash P. Kansagra, Colin P. Derdeyn, Dewitte T. Cross, Christopher J. Moran

Publikováno v: Frontiers in Neurology, Vol 14 (2023)

Tools and techniques utilized in endovascular brain aneurysm treatment have undergone rapid evolution in recent decades. These technique and device-level innovations have allowed for treatment of highly complex intracranial aneurysms and improved pat

Externí odkaz: https://doaj.org/article/90a0deeb834441499af571708c2337e2

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Akademický článek

Propofol Affords No Protection against Delayed Cerebral Ischemia in a Mouse Model of Subarachnoid Hemorrhage

Autor: Meizi Liu, Keshav Jayaraman, James W. Nelson, Jogender Mehla, Deepti Diwan, Ananth K. Vellimana, Gregory J. Zipfel, Umeshkumar Athiraman

Publikováno v: Diseases, Vol 11, Iss 4, p 130 (2023)

Delayed cerebral ischemia (DCI) is an important contributor to poor outcomes in aneurysmal subarachnoid hemorrhage (SAH) patients. We previously showed that volatile anesthetics such as isoflurane, sevoflurane and desflurane provided robust protectio

Externí odkaz: https://doaj.org/article/703fc95edf794188ab4d41cff5f09f5f

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