Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Vellekamp, Gary"'
Autor:
Liu, Yan-Hui, Vellekamp, Gary, Chen, Guodong, Mirza, Urooj A., Wylie, David, Twarowska, Barbara, Tang, John T., Porter, Fred W., Wang, Shihong, Nagabhushan, Tattanahali L., Pramanik, Birendra N.
Publikováno v:
In International Journal of Mass Spectrometry 2003 226(1):55-69
Publikováno v:
Journal of Pharmaceutical Sciences. 97:746-763
Recombinant adenoviruses (rAd), widely used as vectors for gene therapy, are generally purified by column chromatography and frequently contain empty capsids and other aberrant forms of virus particles. To determine particle heterogeneity we utilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f96d5961f545666f22df02f696a57a
https://doi.org/10.1002/jps.21008
https://doi.org/10.1002/jps.21008
Publikováno v:
Human Gene Therapy. 18:286-300
As with certain successful protein drug treatments, the attachment of polyethylene glycol (PEG) molecules to recombinant adenovirus (rAd) can augment their therapeutic potential. Unlike these proteins, the rAd particle has thousands of target sites f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b41012fd74f0fe3e3be69c869115616
https://doi.org/10.1089/hum.2006.172
https://doi.org/10.1089/hum.2006.172
Autor:
Vellekamp, Gary J.1, Kull, Fredrick J.1
Publikováno v:
European Journal of Biochemistry. 8/17/81, Vol. 118 Issue 2, p261-269. 9p.
Autor:
Beth Hutchins, Vellekamp Gary J, Suganto Sutjipto, Todd Machemer, Heidrun Engler, Drake LaFace, Elena Brin, Susan Cannon-Carlson, Douglas Cornell, Mark Horn, Marcio Voloch, Thomas Schluep, Van Tsai, Nico van Rooijen, Dan Maneval, Shu Fen Wen, Seoju Lee, Sundari Ravindran
Publikováno v:
Molecular Therapy. 12:254-263
Intravascular administration of recombinant adenovirus (rAd) in cancer patients has been well tolerated. However, dose-limiting hemodynamic responses associated with suppression of cardiac output have been observed at doses of 7.5 x 10(13) particles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3a5c8f5ba2a07beebcf79024370c4a
https://doi.org/10.1016/j.ymthe.2005.03.007
https://doi.org/10.1016/j.ymthe.2005.03.007
Autor:
Flavia Borellini, Thomas Schluep, Edwige Bonfils, Daniel Malarme, Geoffrey Sharpe, Vellekamp Gary J, Paul W. Shabram, Barry J. Sugarman, Beth Hutchins, Amine Kamen, Shu Wen, Maria Croyle, Michel Koehl, Heike Nesbit, Elisabeth Lehmberg
Publikováno v:
BioProcessing Journal. 2:50-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1c0f1c1b662b2ab0f9f70622124cb76
https://doi.org/10.12665/j23.lehmberg
https://doi.org/10.12665/j23.lehmberg
Autor:
Guodong Chen, Barbara Twarowska, Tattanahali L. Nagabhushan, Vellekamp Gary J, Shihong Wang, Birendra N. Pramanik, John T. Tang, Urooj A. Mirza, Wylie David C, Fred W. Porter, Yan-Hui Liu
Publikováno v:
International Journal of Mass Spectrometry. 226:55-69
The clinical application of recombinant adenoviruses as vectors for gene therapy brings about the need to develop new analytical methodologies for monitoring the quality of the viral production as well as establishing structure–function relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce8627ee9ed177f4cea10926698ad16
https://doi.org/10.1016/s1387-3806(02)00975-2
https://doi.org/10.1016/s1387-3806(02)00975-2
Publikováno v:
BioProcessing Journal. 1:57-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ebac3332bd1f281af79051fbf825f1
https://doi.org/10.12665/j13.vellekamp
https://doi.org/10.12665/j13.vellekamp
Autor:
Grace Michael, Vellekamp Gary J, Leonore C Witchey-Lakshmanan, Peter M. Ihnat, Linda J. Obenauer-Kutner, Jenny Duan, Michelle A Han
Publikováno v:
Biochimica et biophysica acta. 1726(2)
Differential scanning calorimetry was used to identify the thermal stability profile of the replication deficient and protein IX deleted recombinant adenovirus type 5 that contains the p53 transgene (rAd/p53) in phosphate buffered saline (vPBS) or 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8865ae070a1508ef7edef671443787b7
https://pubmed.ncbi.nlm.nih.gov/16023295
https://pubmed.ncbi.nlm.nih.gov/16023295
Publikováno v:
Molecular Therapy. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=base_oa_____::66675cba9e2e7a4842e5bb0d176c390f