Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.

Autor: Ambike S; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Cheng CC; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Feuerherd M; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Velkov S; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Baldassi D; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377 Munich, Germany., Afridi SQ; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Porras-Gonzalez D; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Wei X; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Hagen P; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Kneidinger N; Department of Medicine V, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany., Stoleriu MG; Center for Thoracic Surgery Munich, Ludwig-Maximilians-University of Munich (LMU) and Asklepios Pulmonary Hospital; Marchioninistraße 15, 81377 Munich and Robert-Koch-Allee 2, 82131 Gauting, Germany., Grass V; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany., Burgstaller G; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Pichlmair A; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich partner site, Germany., Merkel OM; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377 Munich, Germany.; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany., Ko C; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.; Infectious Diseases Therapeutic Research Center, Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), 34114 Daejeon, Republic of Korea., Michler T; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich partner site, Germany.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2022 Jan 11; Vol. 50 (1), pp. 333-349.

Prolonged norovirus infections correlate to quasispecies evolution resulting in structural changes of surface-exposed epitopes.

Autor: Afridi SQ; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Usman Z; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, 85354 Freising, Germany., Donakonda S; Institute of Molecular Immunology and Experimental Oncology, Technische Universität München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Wettengel JM; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany., Velkov S; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany., Beck R; Institute of Medical Virology and Epidemiology of Viral diseases, Universitäts Klinikum Tübingen, 72076 Tübingen, Germany., Gerhard M; Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Knolle P; Institute of Molecular Immunology and Experimental Oncology, Technische Universität München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Frishman D; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, 85354 Freising, Germany., Protzer U; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Moeini H; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Hoffmann D; Institute of Virology, Technische Universität/Helmholtz Zentrum München, 81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany.

Publikováno v: IScience [iScience] 2021 Jun 30; Vol. 24 (7), pp. 102802. Date of Electronic Publication: 2021 Jun 30 (Print Publication: 2021).

Active enhancers: recent research advances and insights into disease.

Autor: Zhang, Junyou^1,2,3 (AUTHOR), Wang, Qilin^1,2,3 (AUTHOR), Liu, Jiaxin^1,2,3 (AUTHOR), Duan, Yingying^1,2,3 (AUTHOR), Liu, Zhaoshuo^1,2,3 (AUTHOR), Zhang, Ziyi^1,2,3 (AUTHOR), Li, Chunyan^1,2,3,4 (AUTHOR) lichunyan@buaa.edu.cn

Publikováno v: Biology Direct. 11/12/2024, Vol. 19 Issue 1, p1-16. 16p.

ELISA genotyping of hepatitis B virus in China with antibodies specific for genotypes B and C.

Autor: Li, Yumin¹ (AUTHOR), Wang, Li¹ (AUTHOR), Cheng, Huanyi² (AUTHOR), Chi, Xiumei³ (AUTHOR), Huang, Qingrui² (AUTHOR), Lv, Pinxin⁴ (AUTHOR), Zhang, Wenyi² (AUTHOR), Niu, Junqi⁵ (AUTHOR), Wen, Xiaoyu⁵ (AUTHOR) xywen@jlu.edu.cn, Liu, Zhenning¹ (AUTHOR) liu_zhenning@jlu.edu.cn

Publikováno v: Scientific Reports. 10/12/2024, Vol. 14 Issue 1, p1-15. 15p.

Reply to the Letter of Charre et al. "Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb".

Autor: Usman Z; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, 85354 Freising, Germany., Velkov S; Institute of Virology, Technische Universität München, 81675 Munich, Germany., Protzer U; Institute of Virology, Technische Universität München, 81675 Munich, Germany., Roggendorf M; Institute of Virology, Technische Universität München, 81675 Munich, Germany., Frishman D; Department of Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, 85354 Freising, Germany., Karimzadeh H; Institute of Virology, Technische Universität München, 81675 Munich, Germany.; Division of Clinical Pharmacology, University Hospital, LMU Munich, 80337 Munich, Germany.

Publikováno v: Viruses [Viruses] 2020 Nov 09; Vol. 12 (11). Date of Electronic Publication: 2020 Nov 09.