New age for alignment-free methods for sequence analyses

Autor: Perović, Vladimir, Gemović, Branislava S., Veljković, Nevena V.

Publikováno v: Biologia Serbica : Belgrade BioInformatics Conference : BelBi2021 : program and the book of abstracts; June 21-25

Progress in a wide range of fields ranging from population genetics to precision medicine may be attributed to availability of big biological data. Alignment-free sequence comparison is the methodology of choice in data-intensive applications given t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4175::cd1d9f510a9de614630a47c0c01ab2e6
https://vinar.vin.bg.ac.rs/handle/123456789/11014

Combined in silico and experimental approach to identify the peptide mimetic of the nanobody that stabilize functional conformational state of the beta2 adrenergic receptor (β2AR)

Autor: Senćanski, Milan, Vrecl, Milka, Veljković, Nevena V., Glišić, Sanja

Publikováno v: Biologia Serbica : Belgrade BioInformatics Conference : BelBi2018 : program and the book of abstracts; June 18-22

Stabilization of specific G-protein coupled receptor (GPCR) conformation is achieved by ligand binding to orthosteric or allosteric sites on a GPCRs. A crucial unresolved issue in GPCRs activation/signaling is the role of receptor structural conforma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4175::9d7ce9f34a80f7ff2fb7a1a796227d8d
https://vinar.vin.bg.ac.rs/handle/123456789/11013

Preclinical discovery and development of maraviroc for the treatment of HIV

Autor: Veljković, Nevena V., Vučićević, Jelica, Tassini, Sabrina, Glišić, Sanja, Veljković, Veljko, Radi, Marco

Publikováno v: Expert Opinion on Drug Discovery

Introduction: Maraviroc is a first-in-class antiretroviral (ARV) drug acting on a host cell target (CCR5), which blocks the entry of the HIV virus into the cell. Maraviroc is currently indicated for combination ARV treatment in adults infected only w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4175::7dadf0897bb9456fdccdadea8d7e6083
https://vinar.vin.bg.ac.rs/handle/123456789/558

Can We Use Standard Tools to Predict Functional Effects of Missense Gene Variations Outside Conserved Domains? TET2 Example

Autor: Gemović, Branislava S., Perović, Vladimir R., Glišić, Sanja, Veljković, Nevena V.

Publikováno v: 2nd International Conference “Theoretical Approaches to Bioinformation Systems” (TABIS.2013), September 17-22, 2013, Belgrade, Serbia

The most common genetic variations in humans are Single Nucleotide Polymorphisms (SNPs), so predicting their associations with cancers is a significant issue. Here, we were particularly interested in SNPs occurring outside protein Conserved Domains (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4175::ffaf8f76cccbbb9e417eb822ec906869
https://vinar.vin.bg.ac.rs/handle/123456789/10771

Bioinformatics approach to protein-protein interactions of WT1 isoforms

Autor: Gemović, Branislava S., Perović, Vladimir R., Glišić, Sanja, Veljković, Nevena V.

Publikováno v: FEBS Journal

22nd IUBMB Congress/37th FEBS Congress, Sep 04-09, 2012, Seville, Spain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4175::e5fabe111d8f7244f4a246aa1ee9d4e5
https://hdl.handle.net/21.15107/rcub_vinar_6973