DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division

Autor: Guo, Xiao, Ramirez, Ivan, Garcia, Yenni A., Velasquez, Erick F., Gholkar, Ankur A., Cohn, Whitaker, Whitelegge, Julian P., Tofig, Bobby, Damoiseaux, Robert, Torres, Jorge Z.

Publikováno v: In Journal of Biological Chemistry January-June 2021 296

Mapping Proximity Associations of Core Spindle Assembly Checkpoint Proteins

Autor: Garcia, Yenni A, Velasquez, Erick F, Gao, Lucy W, Gholkar, Ankur A, Clutario, Kevin M, Cheung, Keith, Williams-Hamilton, Taylor, Whitelegge, Julian P, Torres, Jorge Z

Publikováno v: Journal of proteome research, vol 20, iss 7

The spindle assembly checkpoint (SAC) is critical for sensing defective microtubule-kinetochore attachments and tension across the kinetochore and functions to arrest cells in prometaphase to allow time to repair any errors before proceeding into ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c8efacb8d1db09b6d365c64885487809
https://escholarship.org/uc/item/71p9v8ns

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Leukemia Cell Cycle Chemical Profiling Identifies the G2-phase Leukemia Specific Inhibitor Leusin-1

Autor: Silvia Senese, Jorge Z. Torres, Xiaoyu Xia, Ankur A. Gholkar, Erick F. Velasquez, Yu-Chen Lo, Joseph Y. Ong, Robert Damoiseaux

Publikováno v: ACS chemical biology, vol 14, iss 5
Xia, Xiaoyu; Lo, Yu-Chen; Gholkar, Ankur A; Senese, Silvia; Ong, Joseph Y; Velasquez, Erick F; et al.(2019). Leukemia Cell Cycle Chemical Profiling Identifies the G2-phase Leukemia Specific Inhibitor Leusin-1.. ACS chemical biology. doi: 10.1021/acschembio.9b00173. UCLA: Retrieved from: http://www.escholarship.org/uc/item/16b370dx

Targeting the leukemia proliferation cycle has been a successful approach to developing antileukemic therapies. However, drug screening efforts to identify novel antileukemic agents have been hampered by the lack of a suitable high-throughput screeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed2de1f16d2b1efe7be83ea0d556440
https://europepmc.org/articles/PMC6884739/