Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Vekariya P"'
In this paper we propose a novel approach based on knowledge graphs to provide timely access to structured information, to enable actionable technology intelligence, and improve cyber-physical systems planning. Our framework encompasses a text mining
Externí odkaz:
http://arxiv.org/abs/2409.20010
Publikováno v:
Bulletin of Faculty of Physical Therapy, Vol 29, Iss 1, Pp 1-8 (2024)
Abstract Background Stroke survivors and their caregivers have numerous and diverse educational needs, many of which are unmet because of inadequate training from healthcare professionals. As stroke recovery and rehabilitation can continue for years
Externí odkaz:
https://doaj.org/article/98c21db8415c472b8c2297e1e12f1a94
Autor:
Fumiaki Ito, Ziyuan Li, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Robert Betsch, John J. Krais, Bernadette Taberi, Umeshkumar Vekariya, Marissa Calbert, Tomasz Skorski, Neil Johnson, Xiaojiang S. Chen, Richard T. Pomerantz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract DNA polymerase theta (Polθ) is a DNA helicase-polymerase protein that facilitates DNA repair and is synthetic lethal with homology-directed repair (HDR) factors. Thus, Polθ is a promising precision oncology drug-target in HDR-deficient can
Externí odkaz:
https://doaj.org/article/46164b5688fb4f7488433df9b86a86b9
Autor:
Naman S. Shetty, Mokshad Gaonkar, Nirav Patel, Akhil Pampana, Nehal Vekariya, Peng Li, Garima Arora, Pankaj Arora
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Transthyretin is a transport protein whose misfolding has been implicated in the development of cardiac amyloidosis. Here, we examine the clinical correlates of transthyretin levels, the differences in transthyretin levels according to the p
Externí odkaz:
https://doaj.org/article/4a038558f52b4717a5f4e080197ae2aa
Autor:
Umeshkumar Vekariya, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Tatiana Kent, Katherine Sullivan-Reed, Jessica Atkins, Douglas Ralph, Margaret Nieborowska-Skorska, Anna-Mariya Kukuyan, Hsin-Yao Tang, Richard T. Pomerantz, Tomasz Skorski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract DNA polymerase theta (Polθ)-mediated end-joining (TMEJ) repairs DNA double-strand breaks and confers resistance to genotoxic agents. How Polθ is regulated at the molecular level to exert TMEJ remains poorly characterized. We find that Pol
Externí odkaz:
https://doaj.org/article/c0a72ae0a24344bb80638065f6025830
Autor:
Thandavamoorthy Raja, Vinayagam Mohanavel, Sathish Kannan, Vipul Vekariya, Dipen Paul, Palanivel Velmurugan, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Subpiramaniyam Sivakumar
Publikováno v:
Journal of Natural Fibers, Vol 21, Iss 1 (2024)
In the pursuit of sustainable and environmentally friendly engineering materials, this study investigates the potential of Ipomoea carnea fibers (ICF) as a reinforcement agent in bran particulates epoxy matrix used to fabricate the composite laminate
Externí odkaz:
https://doaj.org/article/6df58e09b8f34b419adaa0b870b50f8c
Autor:
Nirav Patel, Naman S. Shetty, Mokshad Gaonkar, Abdulla Shahid, Girija P. Divekar, Akhil Pampana, Nehal Vekariya, Peng Li, Mustafa I. Ahmed, Garima Arora, Pankaj Arora
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)
Background Septal myectomy and alcohol septal ablation (ASA) are septal reduction therapies for patients with symptomatic obstructive hypertrophic cardiomyopathy. Operator and hospital volume may influence outcomes, but contemporary data on this rela
Externí odkaz:
https://doaj.org/article/23d88b01b58046f58fe6eadd6f5752f5
Autor:
Sanmukh Ratilal Joshi, Glenda Millard, Mayuri Vekariya, Priya Radadiya, Manisha Rajapara, Hiren Dhanani, Gaurav Shastri, Prabhat Sharma, Brett Wilson, Yew-Wah Liew
Publikováno v:
Asian Journal of Transfusion Science, Vol 18, Iss 1, Pp 1-6 (2024)
BACKGROUND AND OBJECTIVES: Discrepancy between forward and reverse ABO grouping could be due to several reasons including genetic mutations of the alleles encoding group specific transferase. The healthy donors found with weak A antigen were investig
Externí odkaz:
https://doaj.org/article/906439e5e5d646dd9ff46aa01948089f
Autor:
William Fried, Mrityunjay Tyagi, Leonid Minakhin, Gurushankar Chandramouly, Taylor Tredinnick, Mercy Ramanjulu, William Auerbacher, Marissa Calbert, Timur Rusanov, Trung Hoang, Nikita Borisonnik, Robert Betsch, John J. Krais, Yifan Wang, Umeshkumar M. Vekariya, John Gordon, George Morton, Tatiana Kent, Tomasz Skorski, Neil Johnson, Wayne Childers, Xiaojiang S. Chen, Richard T. Pomerantz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The DNA damage response (DDR) protein DNA Polymerase θ (Polθ) is synthetic lethal with homologous recombination (HR) factors and is therefore a promising drug target in BRCA1/2 mutant cancers. We discover an allosteric Polθ inhibitor (Pol
Externí odkaz:
https://doaj.org/article/a588334634d94054a3dac469d64b47e7
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Modern web application development involves handling enormous amounts of sensitive and consequential data. Security is, therefore, a crucial component of developing web applications. A web application's security is concerned with safeguardin
Externí odkaz:
https://doaj.org/article/9fa6eba6eeb54a2cbf389b08e92e4a3f