Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Veijo T Salo"'
Autor:
Viola Nähse, Camilla Raiborg, Kia Wee Tan, Sissel Mørk, Maria Lyngaas Torgersen, Eva Maria Wenzel, Mireia Nager, Veijo T. Salo, Terje Johansen, Elina Ikonen, Kay Oliver Schink, Harald Stenmark
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cellular homeostasis is governed by removal of damaged organelles and protein aggregates by selective autophagy mediated by cargo adaptors such as p62/SQSTM1. Autophagosomes can assemble in specialized cup-shaped regions of the endoplasmic r
Externí odkaz:
https://doaj.org/article/4b4cc69eb99844d38600776ee09b1dd5
Autor:
Calvin Dumesnil, Lauri Vanharanta, Xavier Prasanna, Mohyeddine Omrane, Maxime Carpentier, Apoorva Bhapkar, Giray Enkavi, Veijo T. Salo, Ilpo Vattulainen, Elina Ikonen, Abdou Rachid Thiam
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Dumesnil et al. report that cholesterol esters (CE), which only melt above body temperature, form supercooled liquid crystalline lipid droplets (LD). Triacylglycerols (TG) solubilize CE to help CE LD nucleation. Through clustering TGs in the ER membr
Externí odkaz:
https://doaj.org/article/1cacaf49d32d4b7a9a98a9bcd3cf7d33
Autor:
Veijo T. Salo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cells store excess energy in the form of lipid droplets (LDs), a specialized sub-compartment of the endoplasmic reticulum (ER) network. The lipodystrophy protein seipin is a key player in LD biogenesis and ER-LD contact site maintenance. Recent struc
Externí odkaz:
https://doaj.org/article/8223157f270e4134b5752d49a5698d27
Autor:
Xavier Prasanna, Veijo T Salo, Shiqian Li, Katharina Ven, Helena Vihinen, Eija Jokitalo, Ilpo Vattulainen, Elina Ikonen
Publikováno v:
PLoS Biology, Vol 19, Iss 1, p e3000998 (2021)
Seipin is a disk-like oligomeric endoplasmic reticulum (ER) protein important for lipid droplet (LD) biogenesis and triacylglycerol (TAG) delivery to growing LDs. Here we show through biomolecular simulations bridged to experiments that seipin can tr
Externí odkaz:
https://doaj.org/article/c8f7f019484345a49fecb9938555c2ef
Publikováno v:
Contact, Vol 3 (2020)
Lipid droplets (LDs) are dynamic cellular hubs of lipid metabolism. While LDs contact a plethora of organelles, they have the most intimate relationship with the endoplasmic reticulum (ER). Indeed, LDs are initially assembled at specialized ER subdom
Externí odkaz:
https://doaj.org/article/5528f8e4d29b46eb8fd7a2add66eab3d
Autor:
Simon G. Pfisterer, Gergana Gateva, Peter Horvath, Juho Pirhonen, Veijo T. Salo, Leena Karhinen, Markku Varjosalo, Samppa J. Ryhänen, Pekka Lappalainen, Elina Ikonen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Lipid droplets (LDs) are cellular organelles dedicated to triacylglycerol storage that can undergo fusion and dissociation events. Here the authors show that formin-like 1-dependent acto-myosin assembly on LDs facilitates their dissociation and, as a
Externí odkaz:
https://doaj.org/article/ed431a9166504d47adae4b3f6abb8d16
Autor:
Herman KH Fung, Yuki Hayashi, Veijo T Salo, Anastasiia Babenko, Ievgeniia Zagoriy, Andreas Brunner, Jan Ellenberg, Christoph W Müller, Sara Cuylen-Haering, Julia Mahamid
Cryo-electron tomography is a powerful label-free tool for visualizing biomolecules in their native cellular context at molecular resolution. However, the precise localisation of biomolecules of interest in the tomographic volumes is challenging. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bad2876500924d70aca9b0da831cb957
https://doi.org/10.1101/2022.12.10.519870
https://doi.org/10.1101/2022.12.10.519870
Autor:
Viola Nähse, Camilla Raiborg, Kia Wee Tan, Sissel Mørk, Maria Lyngaas Torgersen, Eva Maria Wenzel, Mireia Nager, Veijo T. Salo, Terje Johansen, Elina Ikonen, Kay Oliver Schink, Harald Stenmark
Cellular homeostasis is governed by removal of damaged organelles and protein aggregates by selective autophagy mediated by cargo adaptors such as p62/SQSTM1. Autophagosomes can assemble in specialized cup-shaped regions of the endoplasmic reticulum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac318edd18eab870be7b3abf1cc4456
https://doi.org/10.21203/rs.3.rs-1322004/v1
https://doi.org/10.21203/rs.3.rs-1322004/v1
Publikováno v:
Nature Methods. 16:866-869
Auxin-inducible degron technology allows rapid and controlled protein depletion. However, basal degradation without auxin and inefficient auxin-inducible depletion have limited its utility. We have identified a potent auxin-inducible degron system co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ec9e47a423566ab03858e3673decad
https://doi.org/10.1038/s41592-019-0512-x
https://doi.org/10.1038/s41592-019-0512-x
Autor:
Helena Vihinen, Ilpo Vattulainen, Eija Jokitalo, Katharina Ven, Shiqian Li, Veijo T. Salo, Elina Ikonen, Xavier Prasanna
Seipin is a disk-like oligomeric ER protein important for lipid droplet (LD) biogenesis and triacylglycerol (TAG) delivery to growing LDs. Here we show through biomolecular simulations bridged to experiments that seipin can trap TAGs in the ER bilaye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05888717a805fca469d5d6cef4b3bb96
https://doi.org/10.1101/2020.10.26.355065
https://doi.org/10.1101/2020.10.26.355065