FRI-085 - Fibrosis involves increased fibroblast and hepatocyte collagen species, reflecting the interstitial and basement membrane matrix: Restoration of the local tissue milieu with FXR agonism

Autor: Roth, J., Veidal, S., Papazyan, R., Rigbolt, K., Feigh, M., Karsdal, M., Leeming, D., Young, M.

Publikováno v: In Journal of Hepatology April 2018 68 Supplement 1:S399-S399

Circulating levels of citrullinated and MMP-degraded vimentin (VICM) in liver fibrosis related pathology

Autor: Vassiliadis, E., Oliveira, C. P., Alvares-da-Silva, M. R., Zhang, C., Carrilho, F. J., Stefano, J. T., Rabelo, F., Pereira, L., Kappel, C. R., Henriksen, K., Veidal, S. S., Vainer, B., Duffin, K. L., Christiansen, C., Leeming, D. J., Karsdal, M.

Publikováno v: Vassiliadis, E, Oliveira, C P, Alvares-da-Silva, M R, Zhang, C, Carrilho, F J, Stefano, J T, Rabelo, F, Pereira, L, Kappel, C R, Henriksen, K, Veidal, S S, Vainer, B, Duffin, K L, Christiansen, C, Leeming, D J & Karsdal, M 2012, ' Circulating levels of citrullinated and MMP-degraded vimentin (VICM) in liver fibrosis related pathology ', American Journal of Translational Research, vol. 4, no. 4, pp. 403-414 .

Aim: To investigate whether increased levels of vimentin citrullinated peptides identified by MS in articular cartilage can be measured in pathologies other than rheumatoid arthritis and be utilised for diagnostic purposes. Methods: A monoclonal anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::97cca6d29954e81668f5fe93c4d045c4
https://portal.findresearcher.sdu.dk/da/publications/adf1b4bf-6deb-42a2-8d69-48d41da0bf98

FRI-355 - Effects of obeticholic acid and INT-767: a comparison of hepatic and ileal drug concentration and gene expression

Autor: Roth, J., Feigh, M., Veidal, S., Rigbolt, K., Jelsing, J., Vrang, N., Friley, W., Claire, B. St., Hipp, K., Young, M.

Publikováno v: In Journal of Hepatology 2017 66(1) Supplement:S431-S431

PS-027 - FXR agonists with sustained systemic rather than transient intestinal exposure are more efficacious in a diet-induced obese non-alcoholic steatohepatitis mouse model

Autor: Wagner, B., Brigham, D., Lee, K.-J., Ortiz, A., Lu, N., Qian, J., Douglas, K., Nagasawa, J., Govek, S., Feigh, M., Veidal, S., Vrang, N., Song, K., Smith, N.

Publikováno v: In Journal of Hepatology 2017 66(1) Supplement:S18-S19

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