Pyrazolyl-Tetrazoles and Imidazolyl-Pyrazoles as Potential Anticoagulants and their Integrated Multiplex Analysis Virtual Screening

Autor: Lourenço,André L. P. G., Vegi,Percilene F., Faria,Jéssica V., Pinto,Gustavo S. P., Santos,Maurício S. dos, Sathler,Plínio C., Saito,Max S., Santana,Marcos, Dutra,Tatiana P. P., Rodrigues,Carlos R., Monteiro,Robson Q., Bernardino,Alice M. R., Castro,Helena C.

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 30, Issue: 1, Pages: 33-47, Published: JAN 2019
Journal of the Brazilian Chemical Society v.30 n.1 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

This article reports a novel virtual screening algorithm seeking the rational identification of novel lead anticoagulants. Seven 5-(3-methyl-1-aryl-1H-pyrazol-4-yl)-1H-tetrazoles and seven novel 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-3-methyl-1H-pyr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::530540526e8c56a2fc5679b5bb6fb39a
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000100033&lng=en&tlng=en

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Effectiveness of novel 5-(5-amino-1-aryl-1H-pyrazol-4-yl)-1H-tetrazole derivatives against promastigotes and amastigotes of Leishmania amazonensis.

Autor: dos Santos Faiões V; Laboratório de Bioquímica de Tripanosomatídeos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, 21040-900, Brazil., Leon LL, Canto-Cavalheiro MM, Torres-Santos EC, Bernardino AM, Vegi PF, dos Santos MS

Publikováno v: Chemical biology & drug design [Chem Biol Drug Des] 2014 Mar; Vol. 83 (3), pp. 272-7. Date of Electronic Publication: 2013 Oct 30.