Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Veeresa Gududuru"'
Autor:
Koen K. A. Van Rompay, Suma Ramagiri, Gabor Tigyi, Veeresa Gududuru, Hari Kosanam, Duane D. Miller, Fei Ma, Charles R. Yates, Hui He
Publikováno v:
Journal of Chromatography B. 878:2379-2383
Octadecenyl thiophosphate (OTP), a synthetic analogue of the lysophospholipid growth factor lysophosphatidic acid (LPA), significantly reduces mortality following a lethal dose of LD(80/30) radiation exposure in a mouse model of whole-body irradiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3344fe844d497231d5813f5175ee5dc
https://doi.org/10.1016/j.jchromb.2010.07.004
https://doi.org/10.1016/j.jchromb.2010.07.004
Autor:
Leonard R. Johnson, Ryoko Tsukahara, Veeresa Gududuru, Duane D. Miller, Louisa Balazs, E. Shuyu, Gabor Tigyi, Lester VanMiddlesworth, William J. Valentine, Gangadhar Durgam, Venkatraman Manickam, Wenlin Deng, Abby L. Parrill, Marcello Arsura
Publikováno v:
Gastroenterology. 132:1834-1851
Background & Aims: We recently identified lysophosphatidic acid (LPA) as a potent antiapoptotic agent for the intestinal epithelium. The objective of the present study was to evaluate the effect of octadecenyl thiophosphate (OTP), a novel rationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b003ec16ce276d3740183b0ceb0b1427
https://doi.org/10.1053/j.gastro.2007.03.038
https://doi.org/10.1053/j.gastro.2007.03.038
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:4010-4013
In our continuing efforts to develop novel chemotherapeutic agents for prostate cancer, recently we reported the discovery of 2-arylthiazolidine-4-carboxylic acid amides (ATCAAs) as a new class of cytotoxic agents. Several of them were very effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b286ae0f474cafd3be66f1b0a1f1da03
https://doi.org/10.1016/j.bmcl.2005.06.032
https://doi.org/10.1016/j.bmcl.2005.06.032
Publikováno v:
Journal of Medicinal Chemistry. 48:2584-2588
To improve the selectivity and antiproliferative activity of previously reported serine amide phosphates (SAPs), we designed a new series of 4-thiazolidinone amides, in which the 4-thiazolidinone moiety was introduced as a phosphate mimic. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03116b5c7901c8b8fdd07ad9e4f40e5d
https://doi.org/10.1021/jm049208b
https://doi.org/10.1021/jm049208b
Synthesis and antiproliferative activity of 2-aryl-4-oxo-thiazolidin-3-yl-amides for prostate cancer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:5289-5293
We have previously described serine amide phosphates (SAPs) as a novel class of cytotoxic agents for prostate cancer. Several of them showed potent cytotoxicity against human prostate cancer cell lines, but were not selective in non-tumor cells. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a1e638b75d66d98dcc8d322a9abf44
https://doi.org/10.1016/j.bmcl.2004.08.029
https://doi.org/10.1016/j.bmcl.2004.08.029
Autor:
Huiping Xu, Gangadhar G. Durgam, Eunju Hurh, Veeresa Gududuru, Duane D. Miller, Vineet M. Sardar, James T. Dalton, Seoung Soo Hong
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:4919-4923
We describe herein synthesis, SAR, and biological evaluation of a novel series of cytotoxic serine amide phosphates (SAPs) for prostate cancer. These compounds were tested for their cytotoxicity in five human prostate cancer cell lines (DU-145, PC-3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11d963a9d4bc5afc6e88c563114a2f0
https://doi.org/10.1016/j.bmcl.2004.07.026
https://doi.org/10.1016/j.bmcl.2004.07.026
Autor:
Wei, Li, Zhao, Wang, Veeresa, Gududuru, Blazej, Zbytek, Andrzej T, Slominski, James T, Dalton, Duane D, Miller
Publikováno v:
Anticancer research. 27(2)
New drugs are urgently needed for improved therapy for melanoma.Ninety-one novel compounds were evaluated in two melanoma and one normal skin cell lines to identify potential lead compounds with high potency and selectivity. Mechanisms of action for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0abbc137b0327f861a9fb265d8304304
https://pubmed.ncbi.nlm.nih.gov/17465215
https://pubmed.ncbi.nlm.nih.gov/17465215
Autor:
Gabor Tigyi, Yuko Fujiwara, Ryoko Tsukahara, Veeresa Gududuru, Duane D. Miller, Daniel L. Baker, Natalia Makarova, Kathryn R. Pigg, Kui Zeng
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a165a47a0f806066ac77df258e02a2d7
https://doi.org/10.1002/chin.200616165
https://doi.org/10.1002/chin.200616165
Publikováno v:
ChemInform. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::413861e151af6448bf8e27f761e10062
https://doi.org/10.1002/chin.200517127
https://doi.org/10.1002/chin.200517127
Autor:
James T. Dalton, Duane D. Miller, Veeresa Gududuru, Huiping Xu, Eunju Hurh, Gangadhar G. Durgam, Seoung Soo Hong, Vineet M. Sardar
Publikováno v:
ChemInform. 36
We describe herein synthesis, SAR, and biological evaluation of a novel series of cytotoxic serine amide phosphates (SAPs) for prostate cancer. These compounds were tested for their cytotoxicity in five human prostate cancer cell lines (DU-145, PC-3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::140972b0c8224d5b2aa025c24bcad019
https://doi.org/10.1002/chin.200503202
https://doi.org/10.1002/chin.200503202